ChemicalBook >> CAS DataBase List >>Sodium chloroacetate

Sodium chloroacetate

CAS No.
3926-62-3
Chemical Name:
Sodium chloroacetate
Synonyms
sma;SODIUM MONOCHLOROACETATE;sodiuM 2-chloroacetate;smca;SODIUM MONOCHLORACETATE;CHLOROACETIC ACID SODIUM SALT;SMN;SMA3;SMA2;SMA1
CBNumber:
CB9853591
Molecular Formula:
C2H2ClNaO2
Molecular Weight:
116.48
MDL Number:
MFCD00002684
MOL File:
3926-62-3.mol
MSDS File:
SDS
Last updated:2023-11-10 16:48:32

Sodium chloroacetate Properties

Melting point 199 °C (dec.)(lit.)
Density 1.87[at 20℃]
vapor pressure 0.001Pa at 20℃
Flash point 270°C
storage temp. -20°C
solubility 820g/l
form Crystalline Powder
color White
PH 4.5-9.0 (50g/l, H2O, 20℃)
Water Solubility 440 g/L (20 ºC)
Sensitive Hygroscopic
Merck 14,2112
BRN 3597157
Stability Stable. Incompatible with strong oxidizing agents.
LogP -3.8 at 20℃
CAS DataBase Reference 3926-62-3(CAS DataBase Reference)
EWG's Food Scores 1-2
FDA UNII 8D9PZU6L69
EPA Substance Registry System Sodium chloroacetate (3926-62-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS09
Signal word  Danger
Hazard statements  H301-H315-H319-H400
Precautionary statements  P264-P270-P273-P301+P310-P302+P352-P305+P351+P338
Hazard Codes  T,N
Risk Statements  25-38-50-36
Safety Statements  22-37-45-61-26
RIDADR  UN 2659 6.1/PG 3
WGK Germany  2
RTECS  AG1400000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29154000
Toxicity LD50 orally in Rabbit: 95 mg/kg LD50 dermal Rat > 2000 mg/kg
NFPA 704
1
3 1

Sodium chloroacetate price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.20293 Sodium chloroacetate for synthesis 3926-62-3 100g $40 2024-03-01 Buy
Sigma-Aldrich 8.20293 Sodium chloroacetate for synthesis 3926-62-3 500g $53.6 2024-03-01 Buy
Sigma-Aldrich 291773 Sodium chloroacetate 98% 3926-62-3 1kg $55 2024-03-01 Buy
Sigma-Aldrich 291773 Sodium chloroacetate 98% 3926-62-3 3kg $134 2024-03-01 Buy
Alfa Aesar A12379 Sodium chloroacetate, 98% 3926-62-3 250g $22.9 2024-03-01 Buy
Product number Packaging Price Buy
8.20293 100g $40 Buy
8.20293 500g $53.6 Buy
291773 1kg $55 Buy
291773 3kg $134 Buy
A12379 250g $22.9 Buy

Sodium chloroacetate Chemical Properties,Uses,Production

description

Sodium chloroacetate is a white colored powdered solid. It is soluble in water. It may be toxic ingestion or inhalation. It is used as a contact herbicide and a component in other herbicides, an intermediate in the production of carboxymethyl-cellulose, and other synthetic organic chemicals.
Sodium chloroacetate Toxicity list
In one study systemic effects to Sprague-Dawley rats (M/F, numbers per group not indicated) given single doses of sodium chloroacetate at 94, 282, or 470 mg/kg bw demonstrated increased sodium concentration in urine, increased potassium concentration in plasma, and reduced glutathione level in the liver at the highest dose; 2/3 of males died within 24 hours of treatment in the middle and high dose groups.

Stability and Reactivity:

Sodium chloroacetate is stable at normal temperatures and  pressures. Incompatible with oxidizing agents, reducing  agents.

HUMAN USE AND EXPERIENCE

There are a number of case studies of the parent compound,  monochloroacetic acid (MCA), involving corrosion of skin and  eyes and fatalities related to skin absorption of toxicologically  significant amounts of MCA and a health-based target  concentration of 0.1 mg/L was calculated for MCA in drinking  water although Health Canada and Environment Canada have  categorized MCA as not entering the environment at levels that  may be hazardous to human health. There are, however, no  similar data or epidemiological reports for sodium  chloroacetate.

Metabolism/Pharmacokinetics

After absorption, monochloroacetic acid (parent compound  CAS 79-11-8) is converted to thiodiacetic acid and glycolic acid  and is accumulated in the liver and kidneys of rats.Metabolism of sodium monochloroacetate is expected to have a  similar pharmacokinetic profile.

Chemical Properties

Sodium chloroacetate is a white crystalline powder. It is soluble in water. It may be toxic ingestion or inhalation.
Sodium chloroacetate is a reactive and toxic material, so it is hydrolyzed to glycolic acid nearly quantitatively at the end of the production cycle. Chloroacetic acid always contains traces of dichloroacetic acid, a toxic and unreactive material that appears on the California Prop.65 list.

Uses

Sodium chloroacetate is used to prepare dyes and active pharmaceutical ingredients. It is also used as an odor agent, surface active agent and viscosity adjustor.

Uses

Sodium chloroacetate is the sodium salt of chloroacetic acid. It is used to prepare weed killers, dyes, vitamins and active pharmaceutical ingredients. It is also used as an odor agent, surface active agent and viscosity adjustor. Sodium dihydroxyethyltallow glycinate is the condensation product of dihydroxyethyl tallow amine and sodiumchloroacetate.It is used as a thickeningagent and asurfactant.

General Description

Chloroacetic acid sodium salt is a white colored powdered solid. Chloroacetic acid sodium salt is soluble in water.Chloroacetic acid sodium salt may be toxic ingestion or inhalation. Sodium chloroacetate is used as a contact herbicide and a component in other herbicides, an intermediate in the production of carboxymethyl-cellulose, and other synthetic organic chemicals.

Air & Water Reactions

Chloroacetic acid sodium salt is soluble in water.

Reactivity Profile

Salts, basic, such as Chloroacetic acid sodium salt, are generally soluble in water. The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0. They react as bases to neutralize acids. These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

Health Hazard

Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Actin plays an important role in cell motility, structure and integrity. Smooth muscle actin-α (SMA)/ α2-smooth muscle actin (ACTA2) interacts with β-myosin heavy chain and helps in vascular smooth muscle cell contraction. The encoded protein modulates the expression of c-MET (tyrosine-protein kinase Met) and focal adhesion kinase (FAK) in human lung adenocarcinoma cells, which positively and selectively mediates tumor progression. Mutation in the gene expression leads to thoracic aortic aneurysms and dissections (TAAD).

Safety Profile

Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of Cland NazO. Used as an herbicide

79-11-8
3926-62-3
Synthesis of Sodium chloroacetate from Chloroacetic acid
Global( 266)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+86-13288715578 +86-13231137666 sales@hbmojin.com China 12409 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5960 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21703 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29919 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Jinan Finer Chemical Co., Ltd
+86-531-88989536 +86-15508631887 sales@finerchem.com China 2966 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58

Related articles

View Lastest Price from Sodium chloroacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sodium chloroacetate pictures 2023-11-11 Sodium chloroacetate
3926-62-3
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Sodium chloroacetate pictures 2023-09-28 Sodium chloroacetate
3926-62-3
US $10.00-2.00 / kg 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.
Sodium chloroacetate pictures 2023-09-14 Sodium chloroacetate
3926-62-3
US $100.00 / bag 1bag 99 5000 Hebei Fengqiang Trading Co., LTD
Aceticacid,chloro-,sodiumsalt chloro-aceticacisodiumsalt chloroctansodny dowdefoliant Chloroacetic acid sodium salt,98% Sodium chloroacetate, synthesis grade Chloroacetic acid sodiuM salt, 98% 5GR SMA1 SMA2 SMA3 SMN Chloroacetic Acid MonosodiuM Salt, Granular SodiuM chloroacetat FREE SAMPLE NCV SODIUM MONOCHLOROACEETAT E Natriumchloracetat Sodium salt of chloroacetic acid Chloroacetate sodium sodium salt of chloroacetic acid sodium chloroacetate monoxone CHLOROACETIC ACID MONOSODIUM SALT SODIUM CHLOROACETATE Sodum chloroacetate Monochloroacetic Acid Sodium SodiumChloroacetate,>96% Sodiumchloroacetate,98% Sodium chloroacetate 3926-62-3 3926-62-3 Chloroacetic acid sodium salt Acetic acid, 2-chloro-, sodium salt (1:1) Sodium α-Chloroacetate Sodium a-Chloroacetate SODIUM MONOCHLORO ACETATE (SMCA) SODIUM MONOCHLOROACETATE For Synthesis sodiuM 2-chloroacetate sma smca CHLOROACETIC ACID SODIUM SALT SODIUM MONOCHLORACETATE SODIUM MONOCHLOROACETATE Monoclonal Anti-Actin, α-Smooth Muscle - FITC antibody produced in mouse Monoclonal Anti-SMN1 antibody produced in mouse Monoclonal Anti-Actin, α-Smooth Muscle - Alkaline Phosphatase antibody produced in mouse Monoclonal Anti-Actin, α-Smooth Muscle - Cy3? antibody produced in mouse 3926-62-3 C2Cl1H2Na1O2 ClCH2CO2Na ClCH2COONa C2H2CINaO2 C2H2ClNaO2 C2H2ClO2Na Synthetic Reagents Inorganic Salts