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Petrolatum

CAS No.
8009-03-8
Chemical Name:
Petrolatum
Synonyms
PARAFFIN;WAX;VASELINE;PARAFFINUM LIQUIDUM;PETROLEUM JELLY;WAX PARAFFIN;PARAFFINE;White Vaselin;perfecta;TISSUE EMBEDDING MEDIUM (PARAPLAST(R) REGULAR)
CBNumber:
CB9854422
Molecular Formula:
C15H15N
Molecular Weight:
209.2863
MDL Number:
MFCD00147839
MOL File:
8009-03-8.mol
Last updated:2024-03-19 17:34:45

Petrolatum Properties

Melting point 70-80 °C ((ASTM D 127))
Boiling point 322 °C
Density 0.84
refractive index n20/D 1.45
Flash point 198 °C
storage temp. Sealed in dry,Room Temperature
solubility Practically insoluble in acetone, ethanol, hot or cold ethanol (95%), glycerin, and water; soluble in benzene, carbon disulfide, chloroform, ether, hexane, and most fixed and volatile oils.
form extra-low viscosity oil
color white
Specific Gravity 0.815~0.880 (60℃)
PH pH (25℃) : 4.5~8.0
Odor Odorless
Water Solubility Insoluble in water
Dielectric constant 2.0(Ambient)
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
FDA 21 CFR 172.880; 172.886; 178.3700; 178.3710; 573.720; 172.615; 175.105; 175.125; 175.300; 176.170; 176.200; 177.2600; 177.2800; 178.3570; 178.3910; 346.14; 352.70
Substances Added to Food (formerly EAFUS) PETROLATUM
EWG's Food Scores 1-4
NCI Dictionary of Cancer Terms petrolatum; petroleum jelly
FDA UNII 4T6H12BN9U
EPA Substance Registry System Petrolatum (8009-03-8)
Cosmetics Info Petrolatum

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H350
Hazard Codes  T
Risk Statements  45
Safety Statements  24/25-45-53
WGK Germany  3
RTECS  RV0350000
HS Code  27121000
NFPA 704
1
1 0

Petrolatum price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 16415 Vaseline meets analytical specification of Ph. Eur. 8009-03-8 1kg $54.8 2024-03-01 Buy
Sigma-Aldrich 16415 Vaseline meets analytical specification of Ph. Eur. 8009-03-8 6x1kg $254 2024-03-01 Buy
Sigma-Aldrich 16415 Vaseline? meets analytical specification of Ph. Eur. 8009-03-8 10kg $335 2024-03-01 Buy
Frontier Specialty Chemicals JK451485 Petrolatum 8009-03-8 500g $21 2021-12-16 Buy
Frontier Specialty Chemicals JK451485 Petrolatum 8009-03-8 1000g $39 2021-12-16 Buy
Product number Packaging Price Buy
16415 1kg $54.8 Buy
16415 6x1kg $254 Buy
16415 10kg $335 Buy
JK451485 500g $21 Buy
JK451485 1000g $39 Buy

Petrolatum Chemical Properties,Uses,Production

Summary

Petrolatum (Vaseline) is the malthenes purified from lubrication oil, the mixture of residue oil and cerate. It is an important lubricant for medicines, cosmetics, fine chemical raw materials and precision instruments. In China, major vaseline products include ordinary vaseline, industrial vaseline and medical vaseline. Ordinary vaseline is suitable for the preparation of various ointments and softener of dark rubber products; industrial vaseline can be used to protect metal products and general machinery parts against rust and lubricate machines under light loads, but also can be used as treating compound for leather and rubber softener. Vaseline products are mainly concentrated in the medicinal Vaseline, which is divided into two: medical white vaseline and medical yellow Vaseline. Medical Vaseline is mainly used in the preparation of ointment, skin protection cream and cosmetics raw materials, as well as antirust and lubricating materials for medical instruments and precision instruments.

Performance

White or yellow homogeneous paste, almost odorless and tasteless, a mixture of liquid and solid paraffin hydrocarbons. Relative density: 0.815~0.830, viscosity: 0.01 ~ 0.02 Pa•s (100℃), flash point > 190℃ (open type), drop point: about 37~54℃. It is easy to dissolve in ethyl ether, petroleum ether, fatty oil, benzene, carbon disulfide, chloroform and turpentine, difficult to dissolve in ethanol and almost insoluble in water. It is heated into a transparent liquid, which can be fluorescent in the dark after ultraviolet radiation.

Uses

With the characteristics of no color or smell, chemical inertness, semisolid, lipophilic property and good adhesion, it is suitable to manufacture substrates of hair cream, hair conditioner, eye cream, lipstick, wax matrix and so on. Medical petrolatum (vaseline) can be widely used as the matrix of ointment because it is almost compatible with all drugs without changes in drugs. Hydrophilic vaseline can be prepared by adding alcohols such as stearyl alcohol, cetyl alcohol and cholesterol after heated fusion and sufficient stir. Hydrophilic vaseline is an ointment base with strong permeability, stability and small stimulation. This ointment matrix can be used alone for dry skin rash, erythema, papules and other diseases, especially for the removal of blood scab and desquamation. Vaseline can also be used as a non-ionic emulsifier to be compatible with cholesterol, so the range of compatibility is very wide. In addition, it can be compatible with liquid drugs or aqueous solutions of drugs because of its absorbability. Industrial vaseline can be used as rubber softener, anti-rust of metal devices and raw material of rust proof grease.

Production

Acid-carclazyte method
Acid-carclazyte method is a traditional method for the production of petrolatum (vaseline), which is still in use at home and abroad. In the process, add sulfuric acid with more than 98% concentration measured up to about 60% of raw materials and mix it with the raw material in the reactor. The reaction temperature is kept at 70℃. After the reaction, the acid residue is separated and diluted with alcohol to further remove the acid residue. The oil treated with acid in another clay refining tank is decolorized with carclazyte at about 140℃, and then filtered to obtain the final product.
The characteristics of the acid-carclazyte method: the high-quality parts can be produced, PAHs can reach the level of pharmaceutical grade and other relevant indicators can meet the quality index of the pharmacopoeia, which is the reason of traditional craft’s long time existence. The main disadvantage of the method is too low goal product yield (about 50%) and a large number of acid residues which is difficult to be utilized resulting in serious environmental pollution and very high production cost.
Aluminum chloride method
Aluminum chloride method has taken place of acid-carclazyte method to produce vaseline from 60s at home. The process is as follows: the raw material reacts with aluminum chloride after dehydration in the reactor, reaction temperature is between 130℃ to 140℃. After the reaction, the oil will be neutralized and precipitated with alkali liquor in the neutralization tank. Then remove the slag and refine by carclazyte adsorption in the decolorizing tank. Vaseline product is obtained by filtering refined oil at about 120℃. The yield of aluminum chloride method is higher than that of acid-carclazyte method, and consumption index seems lower, but the quality is slightly worse; compared with vaseline produced by medium-pressure hydrocracking and high pressure hydrogenation was there is a great gap in color, transparency, the content of polycyclic aromatic hydrocarbons and so on.
Hydrogenation method
Hydrogenation method is a new process for the production of vaseline, which is usually carried out with 10, 20, or 30MPa and lower liquid hourly space velocity. The process is to convert the useless components in the raw materials into effective components, so that the product yield can be nearly 100%. But aluminum chloride method or acid-carclazyte method changes useless components into waste slags to dump containing effective components, which reduces the product yield. Due to the product yield, the refining extent of luminum chloride method or acid-carclazyte method is also limited, thus limiting the further improvement of product quality. So the hydrogenation method is better than aluminum chloride method and acid-carclazyte method both in product yield or quality.
Economic comparison in three kinds of vaseline production processes
Figure 1. Economic comparison in three kinds of vaseline production processes
Comparison in three wastes from three production processes of vaseline
Figure 2. Comparison in three wastes from three production processes of vaseline

Distinguishing test

Solubility: It is insoluble in water, easily soluble in carbon dioxide, soluble in ether and hexane (OT-42).

Toxicity

Safe for food (FDA, §172.880,2000).
ADI has not been stipulated (FAO/WHO, 2001).

Utilization limit

Baked food 0.15%; candy 0.2%; dehydrated fruits and vegetables 0.02%; solid protein 0.1%(FDA,§172.880,2000).

Chemical properties

A white, yellow or light amber semisolid fatty substance. Transparent when thin-layered, slightly fluorescent. Insoluble in water, almost insoluble in cold or hot ethanol and cold anhydrous ethanol. Soluble in ether, hexane and most volatile or non-volatile oil; easily soluble in benzene, carbon disulfide, chloroform and turpentine.

Uses

Defoamer; lubricant; release agent; protective coating.
The product is suitable for preparing ingredients of medicine ointment and skin protection cream. It can be used for the anticorrosion of mechanical equipments, metal and parts, especially precision instruments, medical equipment and other advanced products. It can be used as lubricating grease in anti-attrition parts of machines when the temperature is not high and the mechanical load is not large. It can be used as the ingredients of high-end cosmetics and other daily necessities, such as skin care cream, hair cream, lipstick pomade ,etc.

Chemical Properties

clear to white solid

Chemical Properties

Petrolatum is a pale yellow to yellow-colored, translucent, soft unctuous mass. It is odorless, tasteless, and not more than slightly fluorescent by daylight, even when melted.

Uses

petrolatum (petroleum jelly; Vaseline) softens and smoothes the skin. It forms a film on the skin’s surface, preventing moisture loss caused by evaporation, and protecting against irritation. Its disadvantage lies in the difficulty of effectively and properly removing it from the skin. Studies indicate that petrolatum accelerates the recovery of skin surface lipids, permeating throughout the stratum corneum layer, and allowing normal barrier recovery despite its occlusive properties. Thus it does not form or act as an impermeable membrane. It is a purified mixture of semisolid hydrocarbons from petroleum. Petrolatum imparts a greasier feeling than other emollients and also has the potential for clogging pores and causing comedogenicity. Although it can cause allergic skin rashes, petrolatum is non-toxic to the skin when properly purified and of high grade.

Uses

Petrolatum is a release agent, lubricant, and defoaming agent that is a purified mixture of semisolid hydrocarbons obtained from petro- leum. it varies in color from white to yellow. it is used in bakery products, dehydrated fruits and vegetables, and egg white solids.

Uses

Pharmaceutic aid (ointment base, oleaginous); Protectant (topical).

Production Methods

Petrolatum is manufactured from the semisolid residue that remains after the steam or vacuum distillation of petroleum.This residue is dewaxed and/or blended with stock from other sources, along with lighter fractions, to give a product with the desired consistency. Final purification is performed by a combination of high-pressure hydrogenation or sulfuric acid treatment followed by filtration through adsorbents. A suitable antioxidant may be added.

Definition

Petrolatum is a complex combination of hydrocarbons obtained as a semi-solid from dewaxing paraffinic residual oil. It consists predominantly of saturated crystalline and liquid hydrocarbons having carbon numbers predominantly greater than C25.

brand name

Moroline (Schering-Plough HealthCare).

General Description

Dark brown, green, amber or white odorless thick liquid. Floats on water.

Reactivity Profile

Petrolatum is unreactive in most circumstances.

Health Hazard

LIQUID: Irritating to eyes.

Fire Hazard

Combustible.

Flammability and Explosibility

Not classified

Pharmaceutical Applications

Petrolatum is mainly used in topical pharmaceutical formulations as an emollient-ointment base; it is poorly absorbed by the skin. Petrolatum is also used in creams and transdermal formulations and as an ingredient in lubricant formulations for medicated confectionery together with mineral oil.
Therapeutically, sterile gauze dressings containing petrolatum may be used for nonadherent wound dressings or as a packing material.Petrolatum is additionally widely used in cosmetics and in some food applications.

Safety Profile

When heated to decomposition it emits acrid smoke and irritating fumes

Safety

Petrolatum is mainly used in topical pharmaceutical formulations and is generally considered to be a nonirritant and nontoxic material.
Animal studies, in mice, have shown petrolatum to be nontoxic and noncarcinogenic following administration of a single subcutaneous 100 mg dose. Similarly, no adverse effects were observed in a 2-year feeding study with rats fed a diet containing 5% of petrolatum blends.
Although petrolatum is generally nonirritant in humans following topical application, rare instances of allergic hypersensitivity reactions have been reported,as have cases of acne, in susceptible individuals following repeated use on facial skin. However, given the widespread use of petrolatum in topical products, there are few reports of irritant reactions. The allergic components of petrolatum appear to be polycyclic aromatic hydrocarbons present as impurities. The quantities of these materials found in petrolatum vary depending upon the source and degree of refining. Hypersensitivity appears to occur less with white petrolatum and it is therefore the preferred material for use in cosmetics and pharmaceuticals.
Petrolatum has also been tentatively implicated in the formation of spherulosis of the upper respiratory tract following use of a petrolatum-based ointment packing after surgery,and lipoid pneumonia following excessive use in the perinasal area.Other adverse reactions to petrolatum include granulomas (paraffinomas) following injection into soft tissue.Also, when taken orally, petrolatum acts as a mild laxative and may inhibit the absorption of lipids and lipid-soluble nutrients.
Petrolatum is widely used in direct and indirect food applications. In the USA, the daily dietary exposure to petrolatum is estimated to be 0.404 mg/kg body-weight.
For further information see Mineral Oil and Paraffin.

storage

Petrolatum is an inherently stable material owing to the unreactive nature of its hydrocarbon components; most stability problems occur because of the presence of small quantities of impurities. On exposure to light, these impurities may be oxidized to discolor the petrolatum and produce an undesirable odor. The extent of the oxidation varies depending upon the source of the petrolatum and the degree of refinement. Oxidation may be inhibited by the inclusion of a suitable antioxidant such as butylated hydroxyanisole, butylated hydroxytoluene, or alpha tocopherol.
Petrolatum should not be heated for extended periods above the temperature necessary to achieve complete fluidity (approximately 70°C).
Petrolatum may be sterilized by dry heat. Although petrolatum may also be sterilized by gamma irradiation, this process affects the physical properties of the petrolatum such as swelling, discoloration, odor, and rheological behavior.
Petrolatum should be stored in a well-closed container, protected from light, in a cool, dry place.

Incompatibilities

Petrolatum is an inert material with few incompatibilities.

Regulatory Status

GRAS listed. Accepted for use in certain food applications in many countries worldwide. Included in the FDA Inactive Ingredients Database (ophthalmic preparations; oral capsules and tablets; otic, topical, and transdermal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Petrolatum Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 345)Suppliers
Supplier Tel Email Country ProdList Advantage
Univar Solutions(China) Co., Ltd.
+8615902132654 ivy.zhuang@univarsolutions.com China 654 58
Hangzhou ICH Biofarm Co., Ltd
+undefined8613073685410 sales@ichemie.com China 985 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21703 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Shanghai Longyu Biotechnology Co., Ltd.
+8615821988213 info@longyupharma.com China 2530 58

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View Lastest Price from Petrolatum manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Petrolatum pictures 2024-03-19 Petrolatum
8009-03-8
US $30.00 / kg 1kg 99.9(%) 30 tons Hebei Yanxi Chemical Co., Ltd.
Petrolatum pictures 2023-12-25 Petrolatum
8009-03-8
US $0.00-0.00 / kg 1kg 99% 1000000 Hebei Jingbo New Material Technology Co., Ltd
Petrolatum pictures 2023-11-01 Petrolatum
8009-03-8
US $0.00-0.00 / kg 25kg >=99% 5000kg Hangzhou ICH Biofarm Co., Ltd
  • Petrolatum pictures
  • Petrolatum
    8009-03-8
  • US $30.00 / kg
  • 99.9(%)
  • Hebei Yanxi Chemical Co., Ltd.
  • Petrolatum pictures
  • Petrolatum
    8009-03-8
  • US $0.00-0.00 / kg
  • 99%
  • Hebei Jingbo New Material Technology Co., Ltd
  • Petrolatum pictures
  • Petrolatum
    8009-03-8
  • US $0.00-0.00 / kg
  • >=99%
  • Hangzhou ICH Biofarm Co., Ltd

Petrolatum Spectrum

protopet,alba protopet,white1s protopet,white2l PETROLEUM WAX PETROLATUM PETROLATUM, WHITE PETROLATUM, YELLOW PARAFFIN LIQUID (HEAVY) PARAFFIN LIQUID (LIGHT) PARAFFIN LIQUID (MEDIUM) PARAFFIN PASTILLE Paraffin scale PARAFFINUM PERLIQUIDUM PARAFFINUM SOLIDUM PARAFFIN WAX 54/57 PEEL AWAY PARAFFIN EMBEDDING WAX industrial vaseline WHITE PARAFFIN WAX FULLY REFINED 60/62 OH PURE PARAFFIN WAX PARAFIN N-PARAFFINE Petrolatum, white, pure VASELINE (WHITE PETROLEUM JELLY) Vaseline Ⅰ YELLOWPETROLATUM MINERALHYDROCARBONS VASELINEP WHITEPETROLATUM VASELINEPETROLEUMJELLY saxoline ultimawhite vasoliment whitepetrolatumusp whitepetroleumjelly whiteprotopet whitevaseline VASELINE WHITE, DAB VASELINE WHITE PHARMACEUTICAL GRADE Paraffin,whitesoft(Vaseline) Vaselinumalbum,1kg Parrafin,Vaselineoil Petroleumjelly/Parrafin~Petrolatumjelly creamwhite extraamber mineralfat mineraljelly paraffinjelly WAX WHITE VASELINE, WHITE VASELINE YELLOW VASELINUM ALBUM VANWAX H SPECIAL POLYFIN(TM) Petrolatum Petrolatum Vaseline,industrial HEICOWAX 6 HISTPARAFFIN FEMA 3216