oxyfenamate
- CAS No.
- 50-19-1
- Chemical Name:
- oxyfenamate
- Synonyms
- P-301;Listica;Al-0361;NSC-108034;oxyfenamate;Oxifenamate;Oxyphenamate;Hydroxyphenamate;(2-hydroxy-2-phenylbutyl) carbamate;(2-hydroxy-2-phenyl-butyl) carbamate
- CBNumber:
- CB9912935
- Molecular Formula:
- C11H15NO3
- Molecular Weight:
- 209.243
- MDL Number:
- MFCD00868145
- MOL File:
- 50-19-1.mol
- MSDS File:
- SDS
| Melting point | 55-56.5° |
|---|---|
| Boiling point | 348.6°C (rough estimate) |
| Density | 1.1547 (rough estimate) |
| refractive index | 1.5080 (estimate) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| FDA UNII | MD0414799X |
SAFETY
Risk and Safety Statements
| Hazard statements | H400 |
|---|---|
| Precautionary statements | P273-P391-P501 |
| Toxicity | LD50 orally in mice: 830 mg/kg (Bastian, Clements) |
oxyfenamate Chemical Properties,Uses,Production
Originator
Listica,Armour,US,1961
Uses
Tranquilizer (minor).
Definition
ChEBI: Oxyfenamate is an alkylbenzene.
Manufacturing Process
2-Phenyl-2-hydroxy-butyl carbamate was prepared by the following method:
49.81 g of 2-phenyl-1,2-butanediol and 25.01 g of pyridine were dissolved in
500 ml of benzene and cooled to 5°C. 34.01 g of ethyl chloroformate was
added over a period of 36 hour at 4°C to 8°C. The reaction mixture was
warmed to room temperature and stirred for 2 hours and then extracted with
100 cc each of the following:
Water, 15% hydrochloric acid, 10% sodium bicarbonate and finally water. The
solvent was stripped off. The residual oil was mixed with 300 ml of 28%
aqueous ammonia for 1 hour. The ammonia and water were vacuum distilled
at a temperature of 40°C or less. Then 300 cc of carbon tetrachloride was
added and the solution dried with sodium sulfate. The solution was cooled at
0°C and then filtered. The crystals were washed with cold carbon tetrachloride
and vacuum dried. The yield was 57 g of dried product having a melting point
of 55°C to 56.5°C.
Therapeutic Function
Tranquilizer
oxyfenamate Preparation Products And Raw materials
oxyfenamate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9309 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 17691182729 18161915376 | 1046@dideu.com | China | 10009 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |