デヒドロ酢酸 化学特性,用途語,生産方法
外観
白色～黄褐色, 結晶～粉末又は塊
定義
本品は、次の化学式で表される環状ケトンである。
溶解性
アセトンに溶ける。エーテル、熱エタノールに易溶。冷エタノールに微溶。水に難溶。アルカリに溶解するが、熱濃アルカリでは分解する。
用途
抗真菌薬として皮膚白癬症に用いられる。また食品の防腐剤としても使用される。チーズ、バター、マーガリンに。清涼飲料水、保存水に。ミソまたはアンなどにも。(食品添加物)
用途
食品および化粧品などの保存料
化粧品の成分用途
防腐剤
化学的特性
Dehydroacetic acid is a white to cream-coloured powder that is only very slightly soluble in water (less than 0.1 %). However, the sodium salt hydrate (CSH7Na04.H20) has a solubility of 33% in water at 25°C, and 48% in propylene glycol. The acid is 22% soluble in acetone, 18% in benzene, and I g dissolves in about 35 ml of ethanol.It is used to reduce pickle bloating, and as a pesticide and preservative for squash and strawberries. Its permissible use level is 65ppm.
Dehydroacetic acid is one of the food additives found in red wine and was determined by ultra-fast liquid chromatography-tandem quadrupole mass spectrometry (UFLC-MS/MS).
To assay dehydroacetic acid, add 500 mg to a 250-ml Erlenmeyer flask and dissolve in 75 ml of neutral alcohol. Following the addition of phenolphthalein T.S., titrate with 0.1 N NaOH to a pink end-point that persists for at least 30 s. Each ml of 0.1 N NaOH = 16.82 mg of dehydroacetic acid (National Academy of Sciences, 1963).
Dehydroacetic acid is a synthetic chemical (no plant-based preservatives that meet our efficacy standards currently exist) that is considered to be a low hazard for human health and for the environment.
使用
Dehydroacetic acid (DHS) is used as stabilizer for cosmetic and pharmaceutical products due to its fungicide and bactericide activity, as additive for PVC-stabilizers and for the syntheses of veterinary medicines. Product Data Sheet
一般的な説明
Dehydroacetic acid is a pyrone derivative, that is typically synthesized by the base-catalyzed dimerization of diketene. It is used as a preservative in pharmaceutical, food and cosmetic products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
安全性プロファイル
Poison by ingestion.
Moderately toxic by intraperitoneal route.
Questionable carcinogen with experimental
tumorigenic data. Combustible when
exposed to heat or flame. When heated to
decomposition it emits acrid smoke and
irritating fumes.
デヒドロ酢酸 上流と下流の製品情報
原材料
準備製品