シクロメチコン 5 化学特性,用途語,生産方法
定義
本品は、次の化学式で表される環状ジメチルシロキサン化合物である。
x：4~6
化粧品の成分用途
エモリエント剤、ヘアコンディショニング剤、溶剤
効能
湿潤剤
化学的特性
Cyclomethicone occurs as a clear, colorless and tasteless volatile liquid.
使用
Pharmaceutic aid (wetting agent).
調製方法
Cyclomethicone is manufactured by the distillation of crude polydimethylsiloxanes.
応用例（製薬）
Cyclomethicone is mainly used in topical pharmaceutical and cosmetic formulations such as water-in-oil creams.
Cyclomethicone has been used in cosmetic formulations, at concentrations of 0.1-50%, since the late 1970s and is now the most widely used silicone in the cosmetics industry. Its high volatility, and mild solvent properties, make it ideal for use in topical formulations because its low heat of vaporization means that when applied to skin it has a ‘dry’ feel.
安全性
Cyclomethicone is generally regarded as a relatively nontoxic and nonirritant material. Although it has been used in oral pharmaceutical applications, cyclomethicone is mainly used in topical pharmaceutical formulations. It is also widely used in cosmetics. Studies of the animal and human toxicology of cyclomethicone suggest that it is nonirritant and not absorbed through the skin. Only small amounts are absorbed orally; an acute oral dose in rats produced no deaths.
貯蔵
Cyclomethicone should be stored in an airtight container in a cool, dry, place.
規制状況(Regulatory Status)
Included in the FDA Inactive Ingredients Database(oral powderfor reconstitution, topical lotion, topical cream, topical emulsion). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
シクロメチコン 5 上流と下流の製品情報
原材料
準備製品