ヒアルロン酸 化学特性,用途語,生産方法
外観
白色粉末~結晶
定義
本品は、グルクロン酸とN-アセチル-D-グルコサミンが結合したムコ多糖である。
解説
ヒアルロン酸,白色の無定形物質.水に可溶.いちじるしく粘度の高い溶液となる.[α]D"-70~-80°(水).分子量 106~107.N-アセチル-D-グルコサミンの C3 位にD-グルクロン酸が,またD-グルクロン酸の C4 位にN-アセチル-D-グルコサミンが交互にβ-グリコシド結合をした多糖.動物組織に広く分布し,ほかの酸性ムコ多糖と共存する.
森北出版「化学辞典(第2版)
特性
ウシの眼のガラス体,さい帯,関節液に多量に存在する.皮膚,項靭帯,大動脈,腱,心臓弁,サメの皮,クジラの軟骨,ヒトの血清,鶏冠粘液水腫,脳などにも見いだされる.ヒアルロン酸はタンパク質と結合して粘ちゅうな状態で接合物質として存在し,細菌や毒物の侵入を防いでいると考えられている.
化粧品の成分用途
皮膚コンディショニング剤、親水性増粘剤
効能
抗リウマチ薬, 瘢痕形成治癒促進薬, 関節機能改善薬
使用
hyaluronic acid is a glycosaminoglycan component. Hyaluronic acid occurs naturally in the dermis. It is thought to play a critical role in healthy skin by controlling the physical and biochemical characteristics of epidermal cells. It also regulates general skin activity, such as water content, elasticity, and the distribution of nutrients. Its water-absorption abilities and large molecular structure allow the epidermis to achieve greater suppleness, proper plasticity, and turgor. Hyaluronic acid is a natural moisturizer with excellent water-binding capabilities. In a solution of 2 percent hyaluronic acid and 98 percent water, the hyaluronic acid holds the water so tightly that it appears to create a gel. However, it is a true liquid in that it can be diluted and will exhibit a liquid’s normal viscous flow properties. When applied to the skin, hyaluronic acid forms a viscoelastic film in a manner similar to the way it holds water in the intercellular matrix of dermal connective tissues. This performance and behavior suggests that hyaluronic acid makes an ideal moisturizer base, allowing for the delivery of other agents to the skin. Manufacturers claim that the use of hyaluronic acid in cosmetics results in the need for much lower levels of lubricants and emollients in a formulation, thereby providing an essentially greaseless product. Furthermore, its ability to retain water gives immediate smoothness to rough skin surfaces and significantly improves skin appearance. For the benefits of hyaluronic acid to be realized in a cosmetic, the product needs to be applied on a regular basis as it is broken down in skin within 24 to 48 hours of application. note, this is not the case with hyaluronic acid injections as the technology used is different.
定義
hyaluronic acid: A glycosaminoglycan(mucopolysaccharide) that ispart of the matrix of connective tissue.Hyaluronic acid binds cells togetherand helps to lubricate joints.It may play a role in the migration ofcells at wounds; this activity ceaseswhen hyaluronidase breaks downhyaluronic acid.
brand name
Equron [Veterinary] (Fort
Dodge Animal Health); Legend (Bayer Animal Health);
Synacid [Veterinary] (Schering-Plough Animal Health).
ヒアルロン酸 上流と下流の製品情報
原材料
準備製品