Dmt-2'fluoro-da(bz) amidite
Dmt-2'fluoro-da(bz) amidite 物理性質
- 貯蔵温度 :
- Inert atmosphere,Store in freezer, under -20°C
- 外見 :
- Powder
- 酸解離定数(Pka):
- 7.87±0.43(Predicted)
- InChIKey:
- ZDIBABNMVQPXHU-JWQXGDSTNA-N
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
Dmt-2'fluoro-da(bz) amidite 価格
もっと(1)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
林純薬工業株式会社
|
99057751 |
DMT-2'-F-dA(Bz)-CE-ホスホロアミダイト 98%
N6-Bz-5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxyadenosine-3'-CE-PhosphoramiditeDMT-2'-F-dA(Bz)-CE Phosphoramidite 98% |
136834-22-5 |
10g |
￥116000 |
2023-06-01 |
購入 |
Dmt-2'fluoro-da(bz) amidite 化学特性,用途語,生産方法
合成
3-((Bis(diisopropylamine)phosphanyl)oxy)propanenitrile (6.42 g, 21.3 mmol, 6.77 mL, 1.8 eq) was added to a solution of N-(9-((2R,3R,4R,5R)-5-((bis(4- methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-9H- purine-6-yl)benzamide (8.0 g, 11.8 mmol, 1.0 eq) in DCM (42 mL) at 0 °C followed by DCI (2.24 g, 18.9 mmol, 1.6 eq). The mixture was warmed to 25 °C and stirred for 3 hours. Two parallel reactions were carried out. The combined remedies were then diluted with DCM (150 mL), the organic layer was washed with sat NaHCO3 solution (200 mL) and brine (100 mL), dried over Na2SO4, filtered and concentrated, the crude was purified by column chromatography to give Dmt-2'fluoro-da(bz) amidite (18.0 g, 18.5 mmol, 78.1% yield, 90% purity) as a white solid.
Dmt-2'fluoro-da(bz) amidite 上流と下流の製品情報
原材料
準備製品
Dmt-2'fluoro-da(bz) amidite 生産企業
Global( 128)Suppliers
- 136834-22-5
- N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoroadenosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
- DMT-2'-F-dA(Bz)-CE Phosphoramidite
- 5'-Dimethoxytrityl-N-Benzoyl-2'-fluoro-3'-[(2-cyanoethyl)-(N,Ndiisopropyl)]-phosphoramidite-deoxyadenosine
- Bz-2'-F-dA Phosphoramidite
- (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite, >97%
- N6-Benzoyl-5'-O-(4,4'-Dimethoxy trityl)-2'-deoxy-2'-fluoroadenosine-3'-O-[(2-cyanoethyl)-(N,N-diiso-propyl)]phosphoramidite
- 5'-DMT-2'-F-Bz-dA Phosphoramidite
- Dmt-2'fluoro-da(bz) amidite
- 2'-F-dA(Bz)-CE Phosphoramidite
- N6-Bz-5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxyadenosine-3'-CE-Phosphoramidite
- Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite
- 2'-F-N6-Bz-dA phosphoramidite
- 2'-DEOXY-2'-FLUORO-N6Bz-ADENOSINE-3'-CE-PHOSPHORAMIDITE
- 2'-fluoro-N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine-3'-CE-Phosphoramidite
- 5'-O-DMT-2'-Fluoro-N6-Benzoyl-2'-deoxyadenosine 3'-CE phosphoramidite
- 5'-O-DMT-2'-F-Benzoyl-Deoxyadenosine-CE Phosphoramidite
- DMT-2'-F-dA(bz) Phosphoramidite
- N6-Bz-5'-O-DMT-2'-fluoro-dA-CE
- 5'-O-DMT-2'-F-N6- Benzoyl-2'-Deoxy Adenosine -3’-Cyanoethyl Phosphoramidite
- 2'-Fluoro-N-Bz Adenosine Amidite
- N6-Benzoyl-5’-O-(4, 4’-dimethoxytrityl)-2’-fluoro-2’-deoxyadenosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
- DMTr-2'-F-dA(Bz)-3'-CE-Phosphoramidite
- 2’-F-dA(Bz) Amidite
- 5'-ODMT-2'-Fluoro-N-Bz Adenosine-3'-OCEPA
- Dmt-2'fluoro-da(bz) amidite
- 2'-F-Bz-A Phosphoramidite
- DMT-2'-F-dA(Bz)-CE Phosphoramidite
- 2'-F-Bz-dA-CE-Phosphoramidite
- 2'-fluoro-N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine-3'-CE-Phosphoramidite