D-(-)-リボース

D-(-)-リボース 化学構造式
50-69-1
CAS番号.
50-69-1
化学名:
D-(-)-リボース
别名:
D-(-)-リボース;リボース;(2R,3R,4R)-2,3,4,5-テトラヒドロキシペンタナール;(-)-D-リボース;D-リボース;D(-)-リボース;D(-)‐リボース;リボース, analytical grade
英語名:
D-Ribose
英語别名:
D-(-)-RIBOSE;(2R,3R,4R)-2,3,4,5-Tetrahydroxypentanal;D-Ribose/D(-)-Ribose;d-ribos;R-RIBOSE;FEMA 3793;RIBOSE, D-(-)-;D-RIB;D-RIBOSE;d-riboRIBOS
CBNumber:
CB1418895
化学式:
C5H10O5
分子量:
150.13
MOL File:
50-69-1.mol
MSDS File:
SDS

D-(-)-リボース 物理性質

融点 :
88-92 °C(lit.)
比旋光度 :
-20.8 º (c=4, H2O)
沸点 :
191.65°C (rough estimate)
比重(密度) :
1.1897 (rough estimate)
FEMA :
3793 | D-RIBOSE
屈折率 :
-21 ° (C=1, H2O)
貯蔵温度 :
2-8°C
溶解性:
H2O: 0.1 g/mL、透明、無色~淡黄色
酸解離定数(Pka):
12.46±0.20(Predicted)
外見 :
結晶性粉末
色:
白~ライトベージュまたはやや黄色
酸塩基指示薬変色域(pH):
7
光学活性 (optical activity):
[α]21/D 19.7°, c = 4 in H2O
水溶解度 :
水に溶ける。エーテルに不溶。
Sensitive :
Hygroscopic
Merck :
14,8204
BRN :
1723081
InChIKey:
HMFHBZSHGGEWLO-SOOFDHNKSA-N
LogP:
-1.47
CAS データベース:
50-69-1(CAS DataBase Reference)
NISTの化学物質情報:
D-Ribose(50-69-1)
EPAの化学物質情報:
D-Ribose (50-69-1)

安全性情報

主な危険性  Xi
Rフレーズ  36/38
Sフレーズ  24/25-37/39-26
WGK Germany  3
RTECS 番号 VJ2275000
3-10
TSCA  Yes
HSコード  29400090
化審法 (8)-48 届出不要化学物質

D-(-)-リボース 価格 もっと(53)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01COBQA-9960 D-リボース
D-Ribose
50-69-1 25g ¥10000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01COBQA-9960 D-リボース
D-Ribose
50-69-1 5g ¥10000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01MAS075407 D-リボース
D-Ribose
50-69-1 500g ¥84600 2024-03-01 購入
東京化成工業 R0025 D-(-)-リボース >98.0%(GC)
D-(-)-Ribose >98.0%(GC)
50-69-1 25g ¥3200 2024-03-01 購入
東京化成工業 R0025 D-(-)-リボース >98.0%(GC)
D-(-)-Ribose >98.0%(GC)
50-69-1 250g ¥18500 2024-03-01 購入

D-(-)-リボース MSDS


D-Ribose

D-(-)-リボース 化学特性,用途語,生産方法

外観

白色~ごくうすい紅色, 結晶性粉末~粉末

用途

リボース(Ribose)は糖の一種で、五炭糖、単糖に分類される。核酸塩基と結合してヌクレオシドを形作っており、リボ核酸の構成糖として知られている。この糖は生体内ではペントースリン酸経路あるいはカルビン-ベンソン回路で作られる。 主要な生体物質 炭水化物 アルコール 糖タンパク質 配糖体 脂質 エイコサノイド 脂肪酸/脂肪酸の代謝中間体 リン脂質 スフィンゴ脂質 ステロイド 核酸 核酸塩基 ヌクレオチド代謝中間体 タンパク質 タンパク質を構成するアミノ酸/アミノ酸の代謝中間体 テトラピロール ヘムの代謝中間体。

説明

D-ribose is an important five-carbon monosaccharide with the chemical formula C5H10O5. It is an important constituent of ribonucleic acid (RNA) and ATP, and plays an important role in the formation of life. It is also an important pharmaceutical intermediate for the production of various nucleic acid drugs.

化学的特性

D-Ribose is a five-carbon sugar with strong water solubility and sweet taste, also known as D-ribofuranose. It is used by all living cells and is an essential component in living organisms for energy production. It is widely present in the furan form.

天然物の起源

Reported found in boiled crab, hen egg, catfish, whitefish, haddock, stored beef, stored veal, milk, applesauce, potato, rapeseed, roasted coffee, fresh coffee and shrimp.

製造方法

D-Ribose is obtained by using D-glucose as a raw material, inserting bacteria or Bacillus subtilis for fermentation, and separating and refining the fermentation product.(By fermentation technology)

定義

ChEBI: D-ribose is a ribofuranose having D-configuration. It is a naturally occurring monosaccharide found in the cells and particularly in the mitochondria is essential in energy production.

生物学の機能

D-ribose is a penta-sugar precursor of some amino acids like glutamate, histidine, proline, and arginine. This substance is transformed into piruvate, enters Krebs's cycle, and has a crucial role in energetic metabolism; it is also involved in glycogen synthesis. The non-oxidative transketolase PPP reaction can be directly synthesized by transferring a keto group to glyceraldehyde 3-phoshate from fructose 6-phosphate. Both these substrates are intermediate products of glycolysis[1].

生物活性

D-ribose is a natural sugar that our bodies produce for a variety of purposes most notably encrgy in the form of ATP(adenosine triphosphate), which powers every cell in our body. Ribose is crucial for the synthesis of energy (ATP) and without it, your cells run out of energy and the health of the cell is compromised. Supplementing with ribose improves cell function by restoring energy.
One of the most vital organs to suffer energy depletion is the heart. That is why so much of the research on D-ribose has focused on the impact of supplement ribose in heart disease. Although ribose is classified as a sugar, when taken orally, it does not have any impact on blood sugar like glucose. Instead, it is used for energy production and energy recovery. Every cell in the body has the capacity to make ribose. But more ribose may be needed than the cell can produce when cells are metabolically stressed, such as with strenuous exercise or disease. When the cells are metabolically stressed they tend to consume more glucose rather than producing more ribose. This can dramatically affect recovery.

副作用

D-ribose is a dietary supplement approved by the US FDA. It is generally considered safe for dosage of ribose is less than 15g/d. However, possible side effects include diarrhea, stomach discomfort, nausea, headache, and low blood sugar.

純化方法

Crystallise -D(-)-ribose from aqueous 80% EtOH, dry it under vacuum at 60o over P2O5 and store it in a vacuum desiccator. It exhibits a complex mutarotation with : [] D 10 -23.1o (1.5minutes), -21.3o (5minutes), -19.5o (10minutes), -19.1o (30minutes), -21.2o (60minutes), -23.1o (120minutes), -23.7o (300minutes), (c 4.5, H2O) [Phelps et al. J Am Chem Soc 56 748 1934]. 1H NMR in D2O at 44o shows 17% -pyranose, 59% -pyranose, 9% -furanose and 15% -furanose forms with furanose -H at 5.34ppm (J 3.0Hz) and -H at 5.31 (J 1.7Hz) [Angyal Adv Carbohydr Chem 42 15 1984, Angyal & Pickles Aust J Chem 25 1711 1972]. The phenylhydrazone crystallises from aqueous pyridine in yellow needles, m 163-164o, and the benzylphenylhydrazone has m 127-128o [Snowden J Am Chem Soc 72 808 1950.] [Beilstein 1 IV 4211.]

D-(-)-リボース 上流と下流の製品情報

原材料

準備製品


D-(-)-リボース 生産企業

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D-(-)-リボース  スペクトルデータ(1HNMR、IR1、IR2、MS、Raman)


50-69-1(D-(-)-リボース)キーワード:


  • 50-69-1
  • D-RIB
  • D(-)-Ribose,99+%
  • RIBONIC ACID-Gamma-LACTONE, D-(+)-(RG)
  • Ribose (300 mg)
  • d-[1-18O]ribose
  • d-[4,5-13C2]ribose
  • D(-)-Ribose 0
  • D-(-)-Ribose Vetec(TM) reagent grade, 99%
  • TEMED ULTRA PURE GRADE
  • D-Ribose, 99.0%+
  • aldehydo-D-ribose
  • D-RIBOSE
  • ALPHA-D-RIBOFURANOSE
  • D(-)Ribose (1.07605)
  • D(minus)ribose cell culture tested
  • ribose, pure
  • D-RIBOSE 98+%
  • D(-)RIBOSE PLANT CELL CULTURE TESTED
  • D-RiboseForBiochemistry
  • D(-)-Ribose, 99.5+%
  • D-Ribose-UL-13C5
  • D-RIBOSE,REAGENT
  • RIBOSE, D-(-)-(RG)
  • D-RIBOSE extrapure
  • D-RIBOSE ULTRA PURE
  • D-RIBOSE, GRANULAR
  • D-RIBOSE, NATURAL
  • D-RIBOSE, POWDER
  • D-Ribose, CP,98%
  • 5-Deoxy-1,2,3-triacetyl-5-deoxy-&beta
  • D-(-)-リボース
  • リボース
  • (2R,3R,4R)-2,3,4,5-テトラヒドロキシペンタナール
  • (-)-D-リボース
  • D-リボース
  • D(-)-リボース
  • D(-)‐リボース
  • リボース, analytical grade
  • ヌクレオシド,ヌクレオチド&関連試薬
  • リボース
  • リボース & 2'-デオキシリボース
  • 単糖&オリゴ糖
  • 生化学
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