イソエタリン 化学特性,用途語,生産方法
効能
気管支拡張薬, β2アドレナリン受容体作動薬
説明
Isoetharine is a direct-acting sympathomimetic with relatively low selectivity with
β2-adrenoreceptors. However, it quickly calms bronchospasms better than more selective
bronchodilators.
使用
Bronchodilator.
一般的な説明
Isoetharine was the first 2-selectivedrug widely used for the treatment of airway obstruction.However, its degree of selectivity and activity for 2-receptors may not approach that of some of the other agentssuch as terbutaline, albuterol, or even ISO. Because of thepresence of the β2-directing β-ethyl group and -directingisopropyl group, isoetharine is a β2-agonist and is resistantto MAO. However, because it contains the catechol ringsystem, it is metabolized by COMT and O-sulfated quiteeffectively. Consequently, it has a short DOA similar to thatof ISO and is used only by inhalation for the treatment ofacute episodes of bronchoconstriction.
イソエタリン 上流と下流の製品情報
原材料
準備製品