ダイレクトブルー1 化学特性,用途語,生産方法
用途
染料
化学的特性
greenish blue powder
使用
Chicago Sky Blue 6B is a counterstain for background autofluorescence in fluorescence and immunofluorescence histochemistry. It helps in the examination of blood plasma permeation.
製造方法
3,3′-Dimethoxylbenzidine double nitriding, in alkaline conditions and 4-Amino-5-hydroxynaphthalene-1,3-disulfonic acid (2 Moore) coupled.
一般的な説明
Bright greenish-blue solid or dark blue powder.
空気と水の反応
Azo dyes can be explosive when suspended in air at specific concentrations. Slightly soluble in water.
反応プロフィール
CHICAGO SKY BLUE 6B is an azo compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. Cleavage of the diazo group by reducing agents may lead to benzidine production.
火災危険
Flash point data for CHICAGO SKY BLUE 6B are not available; however, CHICAGO SKY BLUE 6B is probably combustible.
生物活性
Potent inhibitor of L-glutamate uptake into synaptic vesicles.
安全性プロファイル
An experimental
teratogen. Other experimental reproductive
effects. Mutation data reported. When
heated to decomposition it emits very toxic
fumes of NOx Na2O, and SOx
純化方法
Free it from other electrolytes by adding aqueous sodium acetate to a boiling solution of the dye in distilled water. After standing, the salted-out dye is filtered on a Büchner funnel, the process being repeated several times. Finally, the precipitated dye is boiled several times with absolute EtOH to wash out any sodium acetate, then dried (as the sodium salt) at 105o. [McGregor et al. Trans Faraday Soc 58 1045 1962, Beilstein 16 II 259.]
ダイレクトブルー1 上流と下流の製品情報
原材料
準備製品