(S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt) 化学特性,用途語,生産方法
使用
VPC 12249 has been used as lysophosphatidic acid (LPA)
1/3 receptor antagonist in various experimental studies.
一般的な説明
VPC 12249 is an
N-acyl (oleoyl) serine phosphate-based compound.
Biochem/physiol Actions
Lysophosphatidic acids (LPAs) are bioactive lipid mediators. It interacts with at least six specific LPA receptors (LPA1-6) to mediate extracellular signaling pathway. LPA and its receptors (LPA1-3) are implicated in the pathogenesis of radiation pneumonitis (RP). VPC 12249 (S) inhibits the binding ofLPA to LPA1 and LPA3 receptor.
(S)-phosphoric acid Mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylaMino-propyl] ester (aMMoniuM salt) 上流と下流の製品情報
原材料
準備製品