ANTI-CALRETICULIN

 化学構造式
CAS番号.
化学名:
别名:
英語名:
ANTI-CALRETICULIN
英語别名:
ANTI-CALRETICULIN;ANTI-CALRETICULIN (NT);ANTI-HUMAN CALRETICULIN;ANTI-CALRETICULIN, HUMAN;ANTI-CALRETICULIN MOUSE MAB;ANTI-CALRETICULIN, HUMAN (MOUSE);Anti-CALR (AB2) antibody produced in rabbit;Anti-CALR (AB1) antibody produced in rabbit;Anti-Calreticulin antibody produced in chicken;Anti-Calreticulin antibody produced in rabbit
CBNumber:
CB2684909
化学式:
分子量:
0
MOL File:
Mol file

ANTI-CALRETICULIN 物理性質

貯蔵温度 :
-20°C
外見 :
緩衝水溶液

安全性情報

主な危険性  Xn
Rフレーズ  21/22
Sフレーズ  36/37
WGK Germany  -

ANTI-CALRETICULIN 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
Sigma-Aldrich Japan C4606 IgG fraction of antiserum, buffered aqueous solution
Anti-Calreticulin antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution
0.2ML ¥99400 2024-03-01 購入

ANTI-CALRETICULIN 化学特性,用途語,生産方法

使用

Anti-Calreticulin antibody produced in rabbit has been used in:
  • immunoblotting
  • immunofluorescence
  • immunocytochemistry{91
  • immunoprecipitation

一般的な説明

The gene for calreticulin (CALR) is located on the human chromosome 19p13.13. The encoded protein is a predominantly conserved calcium-binding chaperone, which is localized primarily to the lumen of the endoplasmic reticulum (ER). Calreticulin comprises three domains, a globular N-domain, a proline-rich P-domain, and a highly acidic C-domain.

Biochem/physiol Actions

Calreticulin facilitates transient interaction with newly synthesized cellular and extracellular proteins for folding and assembling in the endoplasmic reticulum (ER) before its localization to the cytosol or cell surface. Calreticulin acts as a lectin-like chaperone binding oligosaccharide residues of newly synthesized N-linked glycoproteins and misfolded proteins. It is believed to play a critical role in quality control processes during protein synthesis and folding and calcium (Ca2+) homeostasis. Increased expression of calreticulin increases the Ca2+ storage capacity of the ER. It also appears to modulate store-operated Ca2+-influx and to alter Ca2+ transport by the sarcoplasmic/ER Ca2+-adenosine triphosphatase (ATPase) (SERCA). Overexpression of calreticulin results in increased sensitivity of HeLa cells to drug-induced apoptosis. However, increased resistance to apoptosis has been observed in calreticulin-deficient cells.

ANTI-CALRETICULIN 上流と下流の製品情報

原材料

準備製品


ANTI-CALRETICULIN 生産企業

Global( 13)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Shanghai guandao biology engineering co., ltd 18818239863 18818239863
3171921642@qq.com China 8889 58

  • ANTI-CALRETICULIN
  • ANTI-CALRETICULIN, HUMAN
  • ANTI-CALRETICULIN, HUMAN (MOUSE)
  • ANTI-CALRETICULIN MOUSE MAB
  • ANTI-CALRETICULIN (NT)
  • Anti-Calreticulin antibody produced in rabbit
  • ANTI-HUMAN CALRETICULIN
  • Anti-CALR (AB2) antibody produced in rabbit
  • Anti-Calreticulin antibody produced in chicken
  • Anti-CALR (AB1) antibody produced in rabbit
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