ジエチルホスホノ酢酸エチル
ジエチルホスホノ酢酸エチル 物理性質
- 融点 :
- -24°C
- 沸点 :
- 142-145 °C9 mm Hg(lit.)
- 比重(密度) :
- 1.13 g/mL at 25 °C(lit.)
- 蒸気圧:
- 0.61Pa at 25℃
- 屈折率 :
- n20/D 1.431(lit.)
- 闪点 :
- 165°C
- 貯蔵温度 :
- Keep in dark place,Sealed in dry,Room Temperature
- 溶解性:
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- 外見 :
- 液体
- 比重:
- 1.130
- 色:
- クリア
- 水溶解度 :
- 水とわずかに混和する。
- BRN :
- 1343714
- InChIKey:
- GGUBFICZYGKNTD-UHFFFAOYSA-N
- LogP:
- 1.13 at 30℃
- CAS データベース:
- 867-13-0(CAS DataBase Reference)
- EPAの化学物質情報:
- Acetic acid, (diethoxyphosphinyl)-, ethyl ester (867-13-0)
ジエチルホスホノ酢酸エチル 価格
もっと(16)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01W0105-0419 |
ジエチルホスホノ酢酸エチル 97.0+% (Capillary GC)
Ethyl Diethylphosphonoacetate 97.0+% (Capillary GC) |
867-13-0 |
25mL |
￥1980 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01W0105-0419 |
ジエチルホスホノ酢酸エチル 97.0+% (Capillary GC)
Ethyl Diethylphosphonoacetate 97.0+% (Capillary GC) |
867-13-0 |
500mL |
￥8900 |
2024-03-01 |
購入 |
|
東京化成工業
|
D1523 |
ホスホノ酢酸トリエチル >97.0%(GC)
Triethyl Phosphonoacetate
>97.0%(GC) |
867-13-0 |
25g |
￥1900 |
2024-03-01 |
購入 |
|
東京化成工業
|
D1523 |
ホスホノ酢酸トリエチル >97.0%(GC)
Triethyl Phosphonoacetate
>97.0%(GC) |
867-13-0 |
100g |
￥3900 |
2024-03-01 |
購入 |
|
関東化学株式会社(KANTO)
|
13970-3A |
ホスホノ酢酸トリエチル 97%
Triethyl phosphonoacetate 97% |
867-13-0 |
500g |
￥38100 |
2024-03-01 |
購入 |
ジエチルホスホノ酢酸エチル 化学特性,用途語,生産方法
外観
無色～わずかにうすい黄色, 澄明の液体
溶解性
エタノール及びアセトンに極めて溶けやすく、水に溶けやすい。
用途
有機合成原料。
説明
Triethyl phosphonoacetate is a reagent for organic synthesis used in the Horner-Wadsworth-Emmons reaction (HWE) or the Horner-Emmons modification. This compound can be added dropwise to sodium methoxide solution to prepare a phosphonate anion. It has an acidic proton that can easily be abstracted by a weak base. When used in an HWE reaction with a carbonyl, the resulting alkene formed is usually the E alkene and is generated with excellent regioselectivity. It can synthesize β-Keto Phosphonates via an acylation reaction of triethyl phosphonoacetate with carboxylic acid chlorides in the presence of magnesium chloride-triethylamine followed by decarbethoxylation. Acylation of triethyl phosphonoacetate using magnesium ethoxide affords acyl phosphonoacetates, which, on treatment with catalytic p-TsOH in water, are converted into 2-aryl-2-oxoalkylphosphonates[1-2].
化学的特性
Triethyl phosphonoacetate is Colorless to light yellow liqui
使用
Triethyl phosphonoacetate serves as a reactant used in Horner-Wadsworth-Emmons reactions, Tsuji-Trost type reactions, Intramolecular Heck-type cyclization and isomerizations and Intramolecular aryne-ene reactions. In Horner-Wadsworth-Emmons reaction, it is utilized as a reagent to prepare chiral 2-methylcyclopropanecarboxylic acid from (S)-propylene oxide.
純化方法
Purify it by fractional distillation, preferably in vacuo. NMR has P resonance at 19.5 relative to orthophosphate. [Kosolapoff & Powell J Am Chem Soc 68 1103 1946, Kosolapoff & Powell J Am Chem Soc 72 4198 1950, Speziale & Freeman J Org Chem 23 1586 1958, Beilstein 4 IV 3613.]
ジエチルホスホノ酢酸エチル 上流と下流の製品情報
原材料
準備製品
ジエチルホスホノ酢酸エチル 生産企業
Global( 528)Suppliers
| 名前 |
電話番号 |
電子メール |
国籍 |
製品カタログ |
優位度 |
|
Jiangxi Sunway Chemical Co., Ltd.
|
+86-0794-5259909 +8615888611133
|
dave@jxswchem.com |
China |
22 |
58 |
|
Jiangxi Sunway Chemical Co., Ltd.
|
+86-0794-5259909 +8615888611133
|
dave@jxswchem.com |
China |
22 |
58 |
|
Hebei Mojin Biotechnology Co., Ltd
|
+8613288715578
|
sales@hbmojin.com |
China |
12453 |
58 |
|
Hebei Yanxi Chemical Co., Ltd.
|
+8617531190177
|
peter@yan-xi.com |
China |
5993 |
58 |
|
Henan Fengda Chemical Co., Ltd
|
+86-371-86557731 +86-13613820652
|
info@fdachem.com |
China |
7377 |
58 |
|
Capot Chemical Co.,Ltd.
|
571-85586718 +8613336195806
|
sales@capotchem.com |
China |
29797 |
60 |
|
Shanghai Daken Advanced Materials Co.,Ltd
|
+86-371-66670886
|
info@dakenam.com |
China |
15371 |
58 |
|
Henan Tianfu Chemical Co.,Ltd.
|
+86-0371-55170693 +86-19937530512
|
info@tianfuchem.com |
China |
21695 |
55 |
|
Hangzhou FandaChem Co.,Ltd.
|
008657128800458; +8615858145714
|
fandachem@gmail.com |
China |
9352 |
55 |
|
Nanjing ChemLin Chemical Industry Co., Ltd.
|
025-83697070
|
product@chemlin.com.cn |
CHINA |
3012 |
60 |
ジエチルホスホノ酢酸エチル スペクトルデータ(1HNMR、13CNMR、IR1、IR2、MS、Raman)
867-13-0(ジエチルホスホノ酢酸エチル)キーワード:
- 867-13-0
- AURORA KA-1452
- ETHOXYCARBONYLMETHANEPHOSPHONIC ACID DIETHYL ESTER
- DIETHYL ETHOXYCARBONYLMETHANEPHOSPHONATE
- PHOSPHONOACETIC ACID TRIETHYL ESTER
- O,O-DIETHYL ETHOXYCARBONYLMETHYL PHOSPHONATE
- ethyldiethoxyphosphorylacetate
- phosphono-aceticacitriethylester
- tl465
- Triethylphosphonaceticacid
- PhosPhonoacetic acid ethyl ester
- Triethyl Phosphonoaceate
- Triethylphosphonoacetate98%
- Trietyl Phosphonoacetate
- TRIETHYLPHOSPHONEACETATE
- Diethyl((ethoxycarbonyl)methyl)phosphonate, 98+ %
- (diethoxyphosphinyl)-aceticaciethylester
- TRIETHYL PHOSPHONOACTETATE
- TRIETHYL PHOSPHONOACETATE
- TRIETHYL CARBOXYMETHYLPHOSPHONATE
- Aceticacid,(diethoxyphosphinyl)-,ethylester
- diethylphosphono-aceticaciethylester
- ethyl(diethoxyphosphinyl)acetate
- Ethyl(diethyoxyphosphoryl)acetate
- Diethyl ethoxycarbonylmethylphosphonate, Triethyl carboxymethylphosphonate
- Ethyl Diethylphosphoneacetate
- Triethyl phosphonoac
- Triethyl phosphonoacetate, Ethyl (diethoxyphosphoryl)acetate
- Triethyl phosphonoacetate, 97% 100GR
- (Diethoxyphosphinyl)acetic acid ethyl
- 2-Oxo-2-ethoxyethylphosphonic acid diethyl ester
- ジエチルホスホノ酢酸エチル
- 2-オキソ-2-エトキシエチルホスホン酸ジエチル
- (ジエトキシホスフィニル)酢酸エチル
- ジエトキシホスフィニル酢酸エチル
- 2-(ジエトキシホスフィニル)酢酸エチル
- エトキシカルボニルメチルホスホン酸ジエチル
- ホスホノ酢酸トリエチル
- トリエチル ホスホノ酢酸
- トリエチルホスホノアセテート
- エトキシカルボニルメタンホスホン酸ジエチル
- ジエチルホスホノ酢酸エチルエステル
- ホルナー-エモンズ反応
- 有機合成化学
- ウィッティヒ & ホルナーエモンズ反応