3-(ピロリジン-2-イル)ピリジン
3-(ピロリジン-2-イル)ピリジン 物理性質
- 融点 :
- 235-236 °C(Solv: ethanol (64-17-5))
- 沸点 :
- 107-108°C 2mm
- 比重(密度) :
- 1,074 g/cm3
- 屈折率 :
- 1.54
- 闪点 :
- 101°C
- 貯蔵温度 :
- 2-8°C
- 溶解性:
- H2O: 50 mg/mL
- 外見 :
- 液体
- 酸解離定数(Pka):
- 9.09±0.10(Predicted)
- 色:
- 黄色
- 比重:
- 1.074
- 水溶解度 :
- アセトン、クロロホルム、水に可溶 (50mg/ml)。
- Merck :
- 14,6712
- BRN :
- 81968
- 安定性：:
- 吸湿性、光に敏感、湿気に敏感
- CAS データベース:
- 5746-86-1(CAS DataBase Reference)
3-(ピロリジン-2-イル)ピリジン 価格
もっと(34)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCN757000 |
(R,S)-ノルニコチン
(R,S)-Nornicotine |
5746-86-1 |
50mg |
￥54300 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCN757000 |
(R,S)-ノルニコチン
(R,S)-Nornicotine |
5746-86-1 |
100mg |
￥58800 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
PHR3063 |
(±)-ノルニコチン pharmaceutical secondary standard, certified reference material
pharmaceutical secondary standard, certified reference material |
5746-86-1 |
50MG |
￥73500 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
N-071 |
(±)-ノルニコチン 溶液 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material
(±)-Nornicotine solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material |
5746-86-1 |
1ml |
￥17300 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
1463371 |
(±)-ノルニコチン United States Pharmacopeia (USP) Reference Standard
Nicotine Related Compound F United States Pharmacopeia (USP) Reference Standard |
5746-86-1 |
20mg |
￥176000 |
2024-03-01 |
購入 |
3-(ピロリジン-2-イル)ピリジン 化学特性,用途語,生産方法
説明
(±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist. The α6 and α7 subunit-containing neuronal nAChRs are particularly responsive to nornicotine with EC
50 values of approximately 4 and 17 μM, respectively, when expressed in
Xenopus oocytes. Nornicotine promotes cell migration and destabilizes cell-cell junctions in an endothelial cell line. It is generally thought to be free from abuse potential, but it has been self-administered by rats. It can be detected in urine.
化学的特性
Colourless Oil
使用
3-(2-Pyrrolidinyl)pyridine is a tobacco alkaloid and the major Nicotine (N412420) metabolite in brain. Nornicotine appears to activate different nAChR subtypes, has a better pharmacokinetic profile, and produces less toxicity than Nicotine. Nornicotine shows a significant analgesic activity. Nicotine USP Related Compound F (3-(pyrrolidine-2-yl)pyridine).
安全性プロファイル
Poison by intraperitoneal route.When heated to decomposition it emits very toxic fumesof NOx and HCl. See also NORNICOTINE
3-(ピロリジン-2-イル)ピリジン 上流と下流の製品情報
原材料
準備製品
3-(ピロリジン-2-イル)ピリジン 生産企業
Global( 192)Suppliers
5746-86-1(3-(ピロリジン-2-イル)ピリジン)キーワード:
- 5746-86-1
- NORNICOTINE, DL-
- (+/-)-NORNICOTINE
- (+-)-1’-demethylnicotine
- beta-dl-nornicotine
- 3-PYRROLIDIN-2-YLPYRIDINE
- 2-[3-PYRIDYL]PYRROLIDINE
- 2-[3-PYRIDYL]PYRROLIDONE
- (+/-)-3-(2-PYRROLIDINYL)PYRIDINE
- 3-(2-PYRROLIDINYL)PYRIDINE
- DL-2-(3-Pyridyl)pyrrolidine
- (+ -)-NORNICOTINE 98+%
- DL-Nornicotine,96%
- 2-(3-Pyridyl)pyrrolidine, 3-(2-Pyrrolidinyl)pyridine
- Nicotine, 1'-demethyl-, (+-)-
- Pyridine, 3-(2-pyrrolidinyl)-, (+-)- (9ci)
- (±)-Nornicotine,2-(3-Pyridyl)pyrrolidine, 3-(2-Pyrrolidinyl)pyridine
- DL-Nornicotine/3-(Pyrrolidin-2-yl)pyridine
- 2-(3-Pyridinyl)pyrrolidine
- 2-(Pyridin-3-yl)pyrrolidine
- (RS)-Nornicotine (1.0 Mg/ML in Methanol)
- 3-(2-Pyrrolidyl)pyridine
- (±)-Nornicotine solution
- Pyridine, 3-(2-pyrrolidinyl)-
- Nicotine Related Compound F
- Nicotine USP RC F
- Nicotine USP Related Compound F (rac-Nicotine EP Impurity F)
- Nicotine Related Compound F (20 mg)
- (2S)-2-(3-Pyridinyl)pyrrolidinium
- (+/-)-nornicotine
- (R,S)-NORNICOTINE
- 3-(ピロリジン-2-イル)ピリジン
- 3-(2-ピロリジニル)ピリジン
- 2-(3-ピリジル)ピロリジン
- (±)-3-(2-ピロリジニル)ピリジン
- (R,S)-ノルニコチン
- ノルニコチン, DL-
- DL-ノルニコチン
- (±)-ノルニコチン 溶液
- DL-ノルニコチン, 98%
- (±)-1′-デメチルニコチン