3',5'-ジニトロ-2',6'-ジメチル-4'-tert-ブチルアセトフェノン 化学特性,用途語,生産方法
用途
除草剤(失効農薬)
化学的特性
It forms yellowish crystals with a sweet, very
persistent, slightly animal musk odor.Musk ketone is prepared by Friedel–Crafts
acetylation of 1,3-dimethyl-5-tert-butylbenzene and nitration of the resulting 2,6-
dimethyl-4-tert-butylacetophenone with nitric acid.
Musk ketone is widely used as a fixative in blossom and fantasy compositions.
天然物の起源
Has apparently not been reported to occur in nature.
使用
Musk ketone is used as fragrance and fixative in after-shave lotions, perfumes, ete.
製造方法
Nitration of the corresponding benzene derivative (Bedoukian, 1967).
一般的な説明
Light yellow crystalline solid. Insoluble in water.
空気と水の反応
Insoluble in water.
反応プロフィール
A nitrated ketone. Ketones are reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.
火災危険
Flash point data is not available for Musk ketone, however, Musk ketone is probably combustible.
純化方法
Purify the ketone by recrystallisation from MeOH. It has a strong odour of musk and is used in perfumery. [Fuson et al. J Org Chem 12 587 1947, Beilstein 7 IV 808.]
3',5'-ジニトロ-2',6'-ジメチル-4'-tert-ブチルアセトフェノン 上流と下流の製品情報
原材料
準備製品