くえん酸トリエチル 化学特性,用途語,生産方法
外観
無色〜わずかにうすい黄色, 澄明の液体
定義
本品は、クエン酸(*)とエタノール(*)とのトリエステルであり、次の化学式で表される。
参照表示名称：クエン酸, エタノール
溶解性
エタノール及びアセトンに極めて溶けやすく、水にやや溶けやすい。
化粧品の成分用途
可塑剤、香料
効能
可塑剤
化学的特性
Triethyl citrate is a clear, viscous, odorless, and practically colorless,
hygroscopic liquid.
天然物の起源
Reported found in Morello cherry, sour cherry and red currant. Also reported found in raw cabbage and white
wine.
使用
Triethyl Citrate is a sequestrant that is an oily liquid, slightly solu-
ble in water. it is found in lemon drinks.
調製方法
Triethyl citrate is prepared by the esterification of citric acid and
ethanol in the presence of a catalyst.
製造方法
By esterification of ethyl alcohol with citric acid.
一般的な説明
Triethyl citrate is a safe direct food additive.
応用例（製薬）
Triethyl citrate and the related esters acetyltriethyl citrate, tributyl
citrate, and acetyltributyl citrate are used to plasticize polymers in
formulated pharmaceutical coatings. The coating applications
include capsules, tablets, beads, and granules for taste masking,
immediate release, sustained-release, and enteric formulations.
Triethyl citrate is also used as a direct food additive for flavoring,
for solvency, and as a surface active agent.
安全性プロファイル
Moderately toxic by
intraperitoneal route. Mildly toxic by
ingestion and inhalation. Combustible liquid
when exposed to heat or flame. To fight
fire, use dry chemical, CO2. When heated to
decomposition it emits acrid smoke and
irritating fumes. See also ESTERS and
CITRIC ACID.
安全性
Triethyl citrate is used in oral pharmaceutical formulations and as a
direct food additive. It is generally regarded as a nontoxic and
nonirritant material. However, ingestion of large quantities may be
harmful.
LD50 (mouse, IP): 1.75 g/kg
LD50 (rat, IP): 4 g/kg
LD50 (rat, oral): 5.9 g/kg
LD50 (rat, SC): 6.6 g/kg
貯蔵
Triethyl citrate should be stored in a closed container in a cool, dry
location. When stored in accordance with these conditions, triethyl
citrate is a stable product.
不和合性
Triethyl citrate is incompatible with strong alkalis and oxidizing
materials.
規制状況(Regulatory Status)
GRAS listed. Accepted for use as a food additive in Europe.
Included in the FDA Inactive Ingredients Database (oral capsules and tablets). Included in the Canadian List of Acceptable Nonmedicinal
Ingredients.
くえん酸トリエチル 上流と下流の製品情報
原材料
準備製品