S-(5'-アデノシル)-L-メチオニン=クロリド二塩酸塩

S-(5'-アデノシル)-L-メチオニン=クロリド二塩酸塩 価格 もっと(6)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01W0101-2751	S-(5'-アデノシル)-L-メチオニン=クロリド二塩酸塩 75.0+% (HPLC) S-(5'-Adenosyl)-L-methionine Chloride Dihydrochloride 75.0+% (HPLC)	86867-01-8	100mg	￥60000	2024-03-01	購入
Sigma-Aldrich Japan	A7007	S-(5′-アデノシル)-L-メチオニンクロリド ≥75% S-(5′-Adenosyl)-L-methionine chloride dihydrochloride ≥75%	86867-01-8	5mg	￥16800	2024-03-01	購入
Sigma-Aldrich Japan	A7007	S-(5′-アデノシル)-L-メチオニンクロリド ≥75% S-(5′-Adenosyl)-L-methionine chloride dihydrochloride ≥75%	86867-01-8	25mg	￥21300	2024-03-01	購入
Sigma-Aldrich Japan	A7007	S-(5′-アデノシル)-L-メチオニンクロリド ≥75% S-(5′-Adenosyl)-L-methionine chloride dihydrochloride ≥75%	86867-01-8	100mg	￥50900	2024-03-01	購入
Sigma-Aldrich Japan	A7007	S-(5′-アデノシル)-L-メチオニンクロリド ≥75% S-(5′-Adenosyl)-L-methionine chloride dihydrochloride ≥75%	86867-01-8	500mg	￥184000	2024-03-01	購入

S-(5'-アデノシル)-L-メチオニン=クロリド二塩酸塩 化学特性,用途語,生産方法

外観

白色～褐色、結晶～粉末

溶解性

水及びエタノールに溶け、アセトンに難溶である。

使用上の注意

アルゴン封入

説明

S-(5''-Adenosyl)-L-methionine chloride (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases. The transfer of a methyl group from SAM to an acceptor produces S-adenosyl-L-homocysteine . SAM is also metabolized by SAM decarboxlase to give decarboxylated SAM, which is involved in the polyamine pathway that generates spermine. Cayman Chemical’s SAM has been purified to remove all S-adenosylhomocysteine, a known inhibitor of most SAM-dependent methyltransferases which is commonly found in other commercially available SAM. In addition, Cayman’s SAM contains no S-methylthioadenosine, a common impurity which may act as a substrate in some assay formats, resulting in high background.

使用

S-(5′-Adenosyl)-L-methionine chloride dihydrochloride has been used as a medium supplement for S30 cell extract. It also has been used for measuring the interaction with catechol-O-methyltransferase (COMT) by quartz crystal microbalance (QCM), surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC) with supported lipid bilayers and vesicles.

一般的な説明

S-(5′-Adenosyl)-L-methionine chloride dihydrochloride (SAM) facilitates the transfer of methyl groups to proteins, lipids and nucleic acids. Methionine adenosyl transferase catalyses the synthesis of SAM from methionine and adenosine triphosphate (ATP). SAM functions to regulate various cellular functions like cell division, cell death, transcription, genetic stability, oxidant/antioxidant balance and polyamine homeostasis. Therapeutically, SAM finds its application as a nutritional supplement in humans for various diseases like osteoarthritis and liver injury. SAM also regulates transsulfuration reactions by binding to the regulatory domain of key enzyme cystathionine-β-synthase (CBS).

S-(5'-アデノシル)-L-メチオニン=クロリド二塩酸塩 上流と下流の製品情報

原材料

準備製品

S-(5'-アデノシル)-L-メチオニン=クロリド二塩酸塩 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19743	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10026	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Hunan Hui Bai Shi Biotechnology Co., Ltd.	0731-85526065 13308475853	ivy@hnhbsj.com	China	4550	62
Shanghai Aladdin Bio-Chem Technology Co.,LTD	18521735133 18521732826;	market@aladdin-e.com	China	25015	65
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	isunpharm@qq.com	China	4428	55
Shanghai Macklin Biochemical Co.,Ltd.	15221275939 15221275939	shenlinxing@macklin.cn	China	15878	55

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• 86867-01-8
• S-(5'-Adenosyl)-L-Methionine chloride dihydrochloride
• SAM chloride dihydrochloride
• 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine chloride dihydrochloride
• S-(5'-Adenosyl)-L-methionine chloride (hydrochloride)
• -Adenosyl)-L-methionine chloride dihydrochloride
• SAM; ADOMET
• S-(5'-Adenosyl)-L-methionine chloride(SAM)
• -Adenosyl)-L-methionine chloride (hydrochloride)
• S-(5'-Adenosyl)-L-methionine chloride dihydrochloride >=75%
• ((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium chloride dihydrochloride
• [(3S)-3-amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium
• S-Adenosyl-L-methionine (chloride dihydrochloride)
• S-(5'-アデノシル)-L-メチオニン=クロリド二塩酸塩
• S-(5′-アデノシル)-L-メチオニンクロリド