ラロキシフェン塩酸塩

ラロキシフェン塩酸塩 価格 もっと(30)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01COBQA-8277	Raloxifene HCl	82640-04-8	1g	￥12500	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01COBQA-8277	Raloxifene HCl	82640-04-8	5g	￥40000	2024-03-01	購入
東京化成工業	R0109	ラロキシフェン塩酸塩 >98.0%(HPLC)(T) Raloxifene Hydrochloride >98.0%(HPLC)(T)	82640-04-8	1g	￥8900	2024-03-01	購入
東京化成工業	R0109	ラロキシフェン塩酸塩 >98.0%(HPLC)(T) Raloxifene Hydrochloride >98.0%(HPLC)(T)	82640-04-8	5g	￥29500	2024-03-01	購入
Sigma-Aldrich Japan	PHR1852	ラロキシフェン 塩酸塩 Pharmaceutical Secondary Standard; Certified Reference Material Raloxifene Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material	82640-04-8	500mg	￥21900	2024-03-01	購入

ラロキシフェン塩酸塩 化学特性,用途語,生産方法

効能

骨粗鬆症治療薬, 選択的エストロゲン受容体モジュレータ (SERM)

商品名

エビスタ (日本イーライリリー)

説明

Raloxifene was launched as Evista in the US for the prevention of postmenopausal osteoporosis. It is noteworthy that this molecule was formerly under development as keoxifene for breast cancer and prostatic hypertrophy. Raloxifene can be prepared by acylation of 6-methoxy-2-(4-methoxyphenyl) benzothiophene followed by simultaneous demethylation of both methoxy groups. Raloxifen is a selective estrogen receptor modulator, exerting antiestrogenic action on certain tissues (breast) and also estrogenic action on bone metabolism or serum lipids. In normal early postmenopausal women, 200 mg daily produced a trend towards suppression of estrogen effects. Raloxifen impeded bone loss in osteoporosis. A two-year study in postmenopausal women with an increased risk for osteoporosis showed that Raloxifen markedly prevented non-traumatic vertebral fractures. Results of several clinical studies demonstrated that Raloxifen appreciably reduced the risk of developing breast cancer. Moreover, it had favourable effect on lipid profiles without having the potential side-effects of estrogen-based therapies. Several extensions for different uses of this molecule are planned, for example growth disorder, obesity, colon tumor and skin atrophy. No serious drug-related events have been reported in the limited number of clinical trials.

化学的特性

Light-Yellow Solid

使用

Raloxifene hydrochloride can be used as a nonsteroidal, selective estrogen receptor modulator (SERM). Antiosteoporotic.

定義

ChEBI: A hydrochloride salt resulting from the reaction of equimolar amounts of raloxifene and hydrogen chloride.

一般的な説明

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

ラロキシフェン塩酸塩 上流と下流の製品情報

原材料

準備製品

ラロキシフェン塩酸塩 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Shanghai Worldyang Chemical Co.,Ltd.	,+86-21-56795779; +8613651600618	sales@worldyachem.com	China	879	58
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	gksales1@gk-bio.com	China	9339	58
Wuhan Godbullraw Chemical Co.,ltd	+undefined18986288449	Alisasales@godbullraw.com	China	560	58
Anhui Zhongda Biotechnology Co., Ltd	+8619956560829	justine@zhongda-biotech.com	China	300	58
Hong Kong Excellence Biotechnology Co., Ltd.	+86-86-18838029171 +8618126314766	ada@sh-teruiop.com	China	893	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	994	58
zhuzhou dingcheng meihei comestic co.,ltd	+undefined18873369619	dingchengbusiness8@163.com	China	241	58
Sigma Audley	+86-18336680971 +86-18126314766	nova@sh-teruiop.com	China	525	58
Shanghai Aosiris new Material Technology Co., LTD	86-15139564871 +8615139564871	wrjmoon2000@163.com	China	352	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55

82640-04-8(ラロキシフェン塩酸塩)キーワード:

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• 82640-04-8
• RALOXIFENE HCL
• Raloxifene hydrochloride,Keoxifene hydrochloride, LY 156758, [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride
• Raloxifene Hydrochloride (200 mg)
• 2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol hydrochloride
• (6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)Methanone hydrochloride
• Evista(Raloxifene Hydrochloride
• (6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)-(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanon
• [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-methanone,hydrochloride (1:1)
• LY156758 (Keoxifene) HCl
• Evista (Raloxifene HCl)
• Methanone,[6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-,hydrochloride (1:1)
• (6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl)-(4-(2-(piperidin-1-yl)ethoxy)phenyl)metha
• RALOXIFENE HYDROCHLORIDE
• KEOXIFENE
• KEOXIFENE HYDROCHLORIDE
• LY 139481
• AKOS 92138
• ly156758
• methanone,(6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidin
• [6-HYDROXY-2-(4-HYDROXYPHENYL)BENZO[B]THIEN-3-YL][4-[2-(1-PIPERIDINYL)ETHOXY]PHENYL]-METHANONE HYDROCHLORIDE
• [6-Hydroxy-2-(4-Hydroxyphenyl) benzo[b]thien-3-yl]
• RALOXIFENEHYDROCHLORIDE(SUBJECTTOPATENTFREE)
• Keoxifene hydrochloride, LY 156758, [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone hydrochloride
• 6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl) ethoxy]phenyl]methanone HCl
• Raloxifene Hydrochloride Tablets
• LY156758 hydrochloride
• CS-127
• LY139481 hydrochloride
• Raloxifene hydrochloride,>98%
• [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone Hydrochloride
• ラロキシフェン塩酸塩
• [6-ヒドロキシ-2-(4-ヒドロキシフェニル)ベンゾ[b]チオフェン-3-イル][4-[2-(1-ピペリジニル)エトキシ]フェニル]メタノン塩酸塩
• ラロキシフェン 塩酸塩
• ラロキシフェン塩酸塩 (JAN)
• 塩酸ラロキシフェン
• エビスタ
• [6-ヒドロキシ-2-(4-ヒドロキシフェニル)ベンゾ[b]チオフェン-3-イル][4-[2-(1-ピペリジニル)エトキシ]フェニル]メタノン・塩酸塩