ChemicalBook English  Chinese  Germany
ChemicalBook > 製品カタログ >化学試薬 >有機試薬 >脂肪酸 >5-フルオロオロチン酸


英語化学名:5-Fluoroorotic acid
英語别名:fo;foa;5-FOA;5' FOA;ro2-9945;nsc31712;ent-26398;Fluoxydin;WR 152520;5-Fluoroorotic
MOL File:703-95-7.mol
5-フルオロオロチン酸 物理性質
融点 : 278 °C (dec.)(lit.)
貯蔵温度 : −20°C
solubility : NH4OH 4 M: 50 mg/mL, clear, faintly yellow
Merck : 4176
CAS データベース: 703-95-7(CAS DataBase Reference)
主な危険性 : Xn,Xi
Rフレーズ : 22-36/37/38
Sフレーズ : 26-36-36/37/39-27
WGK Germany : 3
RTECS 番号: UV7800000
F : 10
Hazard Note : Irritant
国連危険物分類 : IRRITANT

5-フルオロオロチン酸 MSDS

2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid

5-フルオロオロチン酸 化学特性,用途語,生産方法

White to Off-White Crystalline Solid
5-FOA has become a valuable tool for research in the field of molecular genetics. It has been employed in the selection of resistant strains of Saccharomyces cerevisiae that possess a mutant URA3 gene which renders them orotidine-5'-phosphate decarboxylase deficient. 5-FOA is coverted to 5-fluorouridine monophosphate (5-FUMP) in yeast cells, which can become incorporated into RNA or metabolized to the highly toxic 5-fluoro-2’-deoxyuridine monophosphate (5-FdUMP). 5-FdUMP is a potent inhibitor of thymidylate synthase (TS), causing the cessation of DNA synthesis. More recently, 5-FOA has been shown to possess potent antimalarial activity against both chloroquine-susceptible and chloroquine-resistant clones of Plasmodium falciparum. Studies indicate that TS is the primary target of 5-FOA in malarial parasites. The combination of 5-FOA and uracil has been effective in treating mice infected with Plasmodium yoelli. 5-FOA may also have potential in the treatment of human malarial infections when used in combination with other agents.
5-フルオロオロチン酸 上流と下流の製品情報
5-フルオロオロチン酸 生産企業      Global( 184)Suppliers     
Dalian Meilun Biotech Co., Ltd. 0411-66771943;0411-667719420411-66771945sales@meilune.comChina 4853 58
Wuhan HengWo Technology Co., Ltd. 0571-87963082 180625029320571-87963082chemicala@163.comChina 2026 58
J & K SCIENTIFIC LTD. 400-666-7788;market6@jkchemical.comChina 96832 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)sh@meryer.comChina 40403 62
TCI (Shanghai) Development Co., Ltd. 22833 81
Energy Chemical 021-58432009 / 400-005-6266021-58436166-800info@energy-chemical.comChina 44198 61
Wuhan Chemwish Technology Co., Ltd 86-027-6784991286-027-87531808sales@chemwish.comChina 35930 56
Beijing Ouhe Technology Co., Ltd +86-10-4006331231;+86-10-51280831;+86-10-82967028+86-10-82967029sales@ouhechem.comChina 10813 60
BePharm Ltd. (Click here for a quote) 40068-59117; 86-21-51816456-8021/8022/8023+86-21-51816740 (China Mainland); +86-21-51816457 (Others)product@bepharm.comChina 24968 61
Shanghai Sinch Parmaceuticals Tech. Co. Ltd. 11620 64
703-95-7(5-フルオロオロチン酸) キーワード:
オロチン酸一水和物 6-メチルウラシル 5-フルオロウラシル ヒダントイン酸 5-フルオロオロチン酸 オロト酸カリウム 葉酸水和物 くえん酸 5-アミノオロチン酸 グリシン [電気泳動用] オロチン酸
703-95-7 1,2,3,6-tetrahydro-2,6-dioxo-5-fluoro-4-pyrimidinecarboxylicaci 1,2,3,6-tetrahydro-2,6-dioxo-5-fluoro-4-pyrimidinecarboxylicacid 5-fluoro-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylicaci 5-fluoroorotate 5-fluoro-oroticaci ent-26398 fluorooroticacid fo foa nsc31712 ro2-9945 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid 5-FLUOROURACIL-4-CARBOXYLIC ACID 5' FOA 5-FOA 5-FLUOROOROTIC ACID 5-FLUORO-2,6-DIOXO-3H-PYRIMIDINE-4-CARBOXYLIC ACID RARECHEM AH BS 0043 5-FLUOROORTIC ACID 5-Fluoroorotic Fluoxydin Fluoroorotic-Acid (5' FOA) 5-fluorouracil-6-carboxylic acid 5-Fluoroorotic acid monohydrate 98% 5-Fluorooroticacidmonohydrate98% 5-FLUOROOROTIC ACID HYDRATE 99% 4-PYRIMIDINECARBOXYLICACID,5-FLUORO-1,2,3,6-TETRAHYDRO-2,6-DIOXO 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-5-fluoro- WR 152520 5-Fluoro-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid 5-フルオロオロチン酸 5-フルオロ-2,6-ジオキソ-1,2,3,6-テトラヒドロ-4-ピリミジンカルボン酸 1,2,3,6-テトラヒドロ-2,6-ジオキソ-5-フルオロ-4-ピリミジンカルボン酸 5-フルオロ-1,2,3,6-テトラヒドロ-2,6-ジオキソ-4-ピリミジンカルボン酸 5-フルオロオロト酸 5-フルオロオロット酸 5-フルオロオロチン酸N水和物 フルオロオロチン酸 5-フルオロオロチン酸一水和物 ヌクレオシド,ヌクレオチド&関連試薬 フッ素化剤,含フッ素ビルディングブロック&含フッ素生理活性化合物 ヘテロ環化合物 (含フッ素合成ブロック) 含フッ素合成ブロック 核酸塩基と類似体 生化学 有機合成化学
Copyright 2007 © ChemicalBook. All rights reserved