オチロニウムブロミド
オチロニウムブロミド 価格
もっと(7)
メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01COBQC-4672 |
オクチロニウムブロミド
Otilonium bromide |
26095-59-0 |
1g |
¥10000 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01COBQC-4672 |
オクチロニウムブロミド
Otilonium bromide |
26095-59-0 |
5g |
¥12500 |
2024-03-01 |
購入 |
Sigma-Aldrich Japan
|
SML1454 |
≥98% (HPLC)
Otilonium bromide ≥98% (HPLC) |
26095-59-0 |
5mg |
¥17800 |
2024-03-01 |
購入 |
Sigma-Aldrich Japan
|
SML1454 |
≥98% (HPLC)
Otilonium bromide ≥98% (HPLC) |
26095-59-0 |
25mg |
¥72200 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01COBQC-4672 |
オクチロニウムブロミド
Otilonium bromide |
26095-59-0 |
25g |
¥37500 |
2024-03-01 |
購入 |
オチロニウムブロミド 化学特性,用途語,生産方法
効能
鎮痙薬, ムスカリン受容体拮抗薬
説明
Otilonium is an inhibitor of L-type (IC
50 = 2.3 μM) and T-type calcium channels (IC
50s = 0.8, 1.1, and 0.4 μM for Ca
v3.1, Ca
v3.2, and Ca
v3.3, respectively). It is also an antagonist of muscarinic acetylcholine receptors (mAChRs; IC
50s = 0.054, 0.4, 0.222, and 0.156 μM for M
1, M
2, M
4, and M
5 muscarinic receptors, respectively) and the platelet activating factor (PAF) receptor (IC
50 = 0.0552 μM). Otilonium inhibits the inward calcium current in isolated rat colonic smooth muscle cells (EC
50 = 885 nM), an effect that can be blocked by the L-type calcium channel inhibitor nifedipine . It inhibits contractions induced by the muscarinic acetylcholine receptor (mAChR) agonist methacholine in isolated circular muscle of the guinea pig proximal colon (IC
50 = 3.7 μM). Otilonium (4 mg/kg) decreases fecal excretion and wet dog shakes and increases the tail withdrawal latency in the tail-flick test in a rat model of opioid withdrawal syndrome induced by morphine and naloxone.
化学的特性
White Powder
使用
Otilonium bromide is an antimuscarinic
一般的な説明
Otilonium bromide is an antispasmodic. It contains a red color ACh (acetylcholine) like moiety bound to an aromatic system that ends with an octyl ether.
安全性プロファイル
Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of Brí and NOx.
オチロニウムブロミド 上流と下流の製品情報
原材料
準備製品
オチロニウムブロミド 生産企業
Global( 214)Suppliers
オチロニウムブロミド スペクトルデータ(1HNMR)
26095-59-0(オチロニウムブロミド)キーワード:
- 26095-59-0
- Menoctyl
- N,N-Diethyl-N-methy-2-[[4-[[2-(octyloxy)benzoyl]amino]benzoyl]oxy]ethanaminium Bromide
- Pasminox
- SP-63
- Spasen
- Spasmoctyl
- Spasmome
- OTYLONIUMBROMIDE
- diethyl-methyl-[2-[4-[(2-octoxybenzoyl)amino]benzoyl]oxyethyl]azanium bromide
- Aotixiuan
- OtioniuM BroMide
- OtiloniuM broMide(OctyloniuM broMide)
- Octylonium IodideDiscontinued See: O293250
- Ethanaminium, N,N-diethyl-N-methyl-2-[[4-[[2-(octyloxy)benzoyl]amino]benzoyl]oxy]-, bromide (1:1)
- ammonium,diethyl(2-hydroxyethyl)methyl-,bromide,p-(o-(octyloxy)benzamido)ben
- diethyl(2-hydroxyethyl)methylammoniumbromidep-(o-(octyloxy)benzamido)benzoa
- ethanaminium,n,n-diethyl-n-methyl-2-((4-((2-(octyloxy)benzoyl)amino)benzoyl)
- octylonium
- ottiloniobromuro
- n,n-diethyl-n-methyl-2-((4-((2-(octyloxy)benzoyl)amino)benzoyl)oxy)-ethanaminium bromide
- OCTYLONIUM IODIDE
- otilonium bromide
- diethyl(2-hydroxyethyl) methylammonium bromide p-(o-(octyloxy)benzamido)-benzoate
- Doralin
- diethyl-[2-[[4-[[(2-heptoxyphenyl)-oxomethyl]amino]phenyl]-oxomethoxy]ethyl]-methylammonium bromide
- aoixijan
- DORALIN;OCTYLONIUM BROMIDE;SP63;SPASMOMEN
- Otilonium bromide USP/EP/BP
- Otilonium bromideQ: What is
Otilonium bromide Q: What is the CAS Number of
Otilonium bromide Q: What is the storage condition of
Otilonium bromide
- Otilonium
- オチロニウムブロミド
- 臭化オクチロニウム
- スパスモメン
- N,N-ジエチル-N-メチル-2-[4-[(2-オクチルオキシベンゾイル)アミノ]ベンゾイルオキシ]エタンアミニウム·ブロミド
- N,N-ジエチル-N-メチル-2-[[4-[[2-(オクチルオキシ)ベンゾイル]アミノ]ベンゾイル]オキシ]エタンアミニウム·ブロミド
- 臭化オチロニウム
- オクチロニウム·ブロミド
- オクチロニウムブロミド
- N,N-ジエチル-N-メチル-2-[4-[(2-オクチルオキシベンゾイル)アミノ]ベンゾイルオキシ]エタンアミニウム・ブロミド
- N,N-ジエチル-N-メチル-2-[[4-[[2-(オクチルオキシ)ベンゾイル]アミノ]ベンゾイル]オキシ]エタンアミニウム・ブロミド
- オクチロニウム・ブロミド