sec-ブチルアミン 化学特性,用途語,生産方法
外観
無色～ほとんど無色, 澄明の液体
溶解性
水, 多くの有機溶媒と混和する。水に極めて溶けやすい。
用途
農業殺菌剤
用途
(RS)-s-ブチルアミン試験用標準品。
農薬用途
除草剤
説明
Sec-butylamine is an amine of butane. It can be used as a fungicide. It can be used as a fumigant for control of gangrene, skin spot and silver scurf diseases of potato tubers, citrus fruit decay. However, it is highly toxic to aquatic organisms.
化学的特性
colourless liquid with an amine odour
使用
Fungicide.
調製方法
2-Butylamine is manufactured by the condensation of methyl
ethyl ketone with ammonia–hydrogen in the presence of
Ni catalyst. It has been used as a fungistat.
定義
ChEBI: A primary aliphatic amine that is butane in which one hydrogen at position 2 is replaced by an amino group. A fumigant fungicide with a high potential for bioaccumulation, it is not approved for fungicidal use in the European Union.
危険性
Flammable, dangerous fire risk.
健康ハザード
Recommended Personal Protective Equipment: Chemical safety goggles; rubber gloves and apron; respiratory protective equipment; non-sparking shoes; Symptoms Following Exposure: Inhalation causes irritation of burns of the respiratory system; exposure to concentrated vapors can cause asphyxiation. Ingestion causes burns of mouth and stomach. Contact with eyes causes lachrymation, conjunctivitis, burns, corneal edema. Contact with skin causes irritation or burns, dermatitis; General Treatment for Exposure: INHALATION: remove patient from exposure; keep him quiet; contact physician. INGESTION: give large amount of water; induce vomiting; consult a physician. EYES: flush thoroughly with water for 15 min.; call physician immediately. SKIN: remove all contaminated clothing; flood affected area with large quantities of water; consult a physician; Toxicity by Inhalation (Threshold Limit Value): Data not available; Short-Term Exposure Limits: Data not available; Toxicity by Ingestion: Grade 3; oral LD
50 = 380 mg/kg (rat); Late Toxicity: Data not available; Vapor (Gas) Irritant Characteristics: Vapors are moderately irritating such that personnel will not usually tolerate moderate or high concentrations; Liquid or Solid Irritant Characteristics: Severe skin irritant. Causes second- and third-degree burns on short contact and is very injurious to the eyes; Odor Threshold: Data not available.
化学反応性
Reactivity with Water: No reaction; Reactivity with Common Materials: May corrode some metals in presence of water; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Flush with water; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
安全性プロファイル
A poison by ingestion.
A powerful irritant. Moderately toxic by skin
contact. Dangerous fire hazard when
exposed to heat or flame. To fight fire, use
alcohol foam, water spray or mist, dry
chemical. Incompatible with oxidizing
materials. When heated to decomposition it
emits toxic fumes of NOx. A fungicide.
職業ばく露
Alert: (n-isomer): Possible risk of
forming tumors, suspected of causing genetic defects, suspected reprotoxic hazard, Primary irritant (w/o allergic
reaction), (sec-isomer): Drug. n-Butylamine is used in
pharmaceuticals; dyestuffs, rubber, chemicals, emulsifying
agents; photography, desizing agents for textiles; pesticides, and synthetic agents. sec-Butylamine is used as a
fungistate. tert-Butylamine is used as a chemical intermediate in the production of tert-Butylaminoethyl methacrylate
(a lube oil additive); as an intermediate in the production
of rubber and in rust preventatives and emulsion deterrents
in petroleum products. It is used in the manufacture of
several drugs
輸送方法
UN1125 n-Butylamine, Hazard Class: 3; Labels:
3—Flammable liquid, 8—Corrosive material. UN2014
Isobutylamine, Hazard Class: 3; Labels: 3—Flammable
liquid, 8—Corrosive material
不和合性
May form explosive mixture with air.
May accumulate static electrical charges, and may causeignition of its vapors. n-Butylamine is a weak base; reacts
with strong oxidizers and acids, causing fire and explosion
hazard. Incompatible with organic anhydrides; isocyanates,
vinyl acetate; acrylates, substituted allyls; alkylene oxides;
epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks some metals in
presence of moisture. The tert-isomer will attack some
forms of plastics
廃棄物の処理
Use a licensed professional
waste disposal service to dispose of this material. Dissolve
or mix the material with a combustible solvent and burn in
a chemical incinerator equipped with an afterburner andscrubber. All federal, state, and local environmental regulations must be observed.
参考文献
Smilanick, J. L., and J. W. Eckert. "Growth, sporulation, and virulence of isolates of Penicillium digitatum resistant to the fungicide sec-butylamine. " Phytopathology 76.8(1986).
Graham, D. C., et al. "Use of 2-aminobutane as a fumigant for control of gangrene, skin spot and silver scurf diseases of potato tubers." Potato Research 16.2(1973):109-125.
Gutter, Y. "Combined treatment with thiabendazole and 2-aminobutane for control of citrus fruit decay." Crop Protection 4.3(1985):346-350.
sec-ブチルアミン 上流と下流の製品情報
原材料
準備製品