アンチマイシンA 化学特性,用途語,生産方法
解説
アンチマイシンAは，放線菌 Streptomyces のある種から得られる抗生物質。 A1，A3 など数種類の混合物である。呼吸を阻害するが，これは電子伝達系のうちチトクロム6とチトクロム C1 の間に作用して，電子伝達を妨げるからである。
ブリタニカ国際大百科事典 小項目事典 ブリタニカ
化学的特性
Antimycin (A3C26H36N2O9) and (Antimycin
A1) C28H40N2O9 are crystalline solids.
使用
Antimycin A is a complex of related macrocyclic lactones, predominantly A1 to A4, isolated from several species of Streptomyces, first reported in the early 1950s for potent antifungal activity. There are over 20 known analogues in the antimycin A class, mostly involving variation of the fatty acid ester chain length or adjacent alkyl starting unit. Antimycin A binds to cytochrome C reductase at the Qi site, inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A is widely used as a bioprobe of respiration and other applications with over 5,000 literature citations.
一般的な説明
Solid. Specific uses for ANTIMYCIN A were not found. ANTIMYCIN A1,and ANTIMYCIN A3 are reported as antibiotics produced by Streptomyces for use as a fungicide and possibly as an insecticide and miticide. Registered only as a pesticide in the U.S.
火災危険
When heated to decomposition, ANTIMYCIN A emits toxic fumes of oxides of nitrogen.
农业用途
Fungicide, Piscicide: A U.S. EPA restricted Use Pesticide (RUP). May
also be used as an insecticide.
製品名
FINTROL®; VIROSIN®
安全性プロファイル
Poison by ingestion,intraperitoneal, subcutaneous, and intravenous routes.When heated to decomposition it emits toxic fumes ofNOx.
職業ばく露
Specific uses for antimycin A were
not found, however, antimycin A1, and antimycin A3 are
reported to be antibiotic substances produced by streptomyces
for use as a fungicide, possible insecticide and miticide.
Registered as a pesticide in the U.S.
輸送方法
UN2811 Toxic solids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required.
アンチマイシンA 上流と下流の製品情報
原材料
準備製品