2'-O-MOE-A(Bz)-3'-phosphoramidite
2'-O-MOE-A(Bz)-3'-phosphoramidite 物理性質
- 酸解離定数(Pka):
- 7.87±0.43(Predicted)
- InChIKey:
- VPBYBQBHLYRLHG-VCCSSPGHNA-N
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
|
| 注意喚起語 |
|
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
|
P264, P270, P301+P312, P330, P501 |
|
| 注意書き |
| P264 |
取扱い後は皮膚をよく洗うこと。 |
| P264 |
取扱い後は手や顔をよく洗うこと。 |
| P270 |
この製品を使用する時に、飲食または喫煙をしないこ と。 |
| P301+P312 |
飲み込んだ場合：気分が悪い時は医師に連絡する こと。 |
| P330 |
口をすすぐこと。 |
| P501 |
内容物/容器を．．．に廃棄すること。 |
|
2'-O-MOE-A(Bz)-3'-phosphoramidite 価格
もっと(5)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01CHGANP-4141[AKTA] |
2'-MOE-Adenosine (N-Bz)-3'-CEP [Bottle for Akta] |
251647-53-7 |
1g |
￥25200 |
2021-03-23 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01CHGANP-4141[AKTA] |
2'-MOE-Adenosine (N-Bz)-3'-CEP [Bottle for Akta] |
251647-53-7 |
2g |
￥50400 |
2021-03-23 |
購入 |
|
林純薬工業株式会社
|
99057755 |
DMT-2'-O-MOE-A(Bz)-CE- ホスホロアミダイト 98%
N6-benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl PhosphoramiditeDMT-2'-O-MOE-A(Bz)-CE Phosphoramidite 98% |
251647-53-7 |
10g |
￥100000 |
2023-06-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01CHGANP-4141[EX] |
2'-MOE-Adenosine (N-Bz)-3'-CEP [Bottle for Expedite] |
251647-53-7 |
1g |
￥25200 |
2021-03-23 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01CHGANP-4141[EX] |
2'-MOE-Adenosine (N-Bz)-3'-CEP [Bottle for Expedite] |
251647-53-7 |
2g |
￥50400 |
2021-03-23 |
購入 |
2'-O-MOE-A(Bz)-3'-phosphoramidite 化学特性,用途語,生産方法
説明
2'-O-MOE-A(Bz)-3'-phosphoramidite, also known as DMT-2'-O-MOE-rA(Bz) phosphoramidite, inserts 2'-O-methoxyethyl-modified adenosine into oligonucleotide phosphoramidites for antisense RNA. Its 2'-MOE backbone bolsters duplex stability, nuclease resistance, and has low toxicity, contributing to effective, safe genetic manipulation. It is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
化学的特性
The IUPAC name of 2'-O-MOE-A(Bz)-3'-phosphoramidite is (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. It is white to off-white powder.
2'-O-MOE-A(Bz)-3'-phosphoramidite 上流と下流の製品情報
原材料
準備製品
2'-O-MOE-A(Bz)-3'-phosphoramidite 生産企業
Global( 106)Suppliers
251647-53-7()キーワード:
- 251647-53-7
- 2'-O-MOE-A(Bz)-3'-phosphoramidite
- N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)adenosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- ADENOSINE, N-BENZOYL-5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-(2-METHOXYETHYL)-, 3'-[2-CYANOETHYL BIS(1-METHYLETHYL)PHOSPHORAMIDITE] (9CI)
- 2'-O-MOE-Bz-A Phosphoramidite
- N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
- 2'-O-MOE-A(Bz)-CE Phosphoramidite
- 5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-ME-A(BZ) PHOSPHORAMIDITE
- DMT-2'-O-MOE-A(Bz)-CE-Phosphoramidite
- N6-benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl Phosphoramidite
- Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- N6-Benzoyl-5’-O-(4,4’-dimethoxy-trityl)-2’-O-(2-methoxyethyl)adeno sine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite
- 2'-O-MOE-rA(Bz) Phosphoramidite)
- 5'-O-DMT-N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
- Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite
- 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-N6-benzoyl-adenosine -3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- 5'-DMTr-2'-MOE-N6-Bz-3'-CEP-Adenosine
- 5'-DMTr-2'-MOE-N6Bz-3'-O-CEP-ADENOSINE
- DMT-2′O-MOE-rA(bz) Phosphoramidite
- 2’-O-MOE-A(Bz)-3’-phospho ramidite, N6-Benzoyl-5’-O-(4,4’-dimethoxy-trityl)-2’-O-(2-methoxyethyl)adeno sine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite
- N6-Bz-5’-O-DMTr-2’-O-(2-methoxyethyl)-adenosine-3’-CED-phosphoramidite
- N6-Bz-5'-O-DMT-2'-O-MOE-A-CE
- 5'-O-DMT-2'-O-MOE-A(Bz)-CE Phosphoramidite
- 2'-MOE-Bz-A CE Phosphoramidite
- 5'-O-DMT-2'-O-MOE-N6-Benzoyl- Adenosine -3’-Cyanoethyl Phosphoramidite
- 2'-MOE-N-Bz Adenosine Amidite
- DMT-2'-O-MOE-A(Bz)-CE
- DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite
- 2’-MOE-dA(Bz) Amidite
- N6-Benzoyl-2-o-methyladenosine 3-ce phosphoramidite
- N6-Benzoyl-5’-O-(4, 4’-dimethoxytrityl)-2’-O-(2-methoxyethyl)adenosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite