リポタンパク質, 低密度 ヒト血漿由来
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- CAS番号.
- 308068-14-6
- 化学名:
- リポタンパク質, 低密度 ヒト血漿由来
- 别名:
- リポタンパク質, 低密度 ヒト血漿由来
- 英語名:
- LDL
- 英語别名:
- LDL;LDL, HUMAN;LIPOPROTEIN;BETA-LIPOPROTEIN;LIPOPROTEIN HUMAN;LOW DENSITY LIPOPROTEIN;LIPOPROTEIN, LOW DENSITY;LIPOPROTEIN, LOW DENSITY, HUMAN;LIPOPROTEINS, LOW DENSITY, HUMAN;LIPOPROTEIN, LOW DENSITY, HUMAN PLASMA
- CBNumber:
- CB9117084
- 化学式:
- 分子量:
- 0
- MOL File:
- Mol file
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リポタンパク質, 低密度 ヒト血漿由来 価格
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製品番号 |
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リポタンパク質, 低密度 ヒト血漿由来 化学特性,用途語,生産方法
解説
リポタンパク質，脂質とタンパク質の複合体の総称。大腸菌外膜の構成成分であるリポタンパク質のように，タンパク質部分と共有結合で結合した脂肪酸をもつ不溶性タンパク質もあるが，通常は血漿（けつしよう），卵黄，ミルクなどに存在する水溶性のものを指す。血漿中のものは比重の小さいものから，カイロミクロンchylomicron，超低密度リポタンパク質(VLDL)，低密度リポタンパク質(LDL)，高密度リポタンパク質(HDL)，超高密度リポタンパク質(VHDL)に分類され，それぞれの間で脂質，タンパク質組成が異なる。
使用
Lipoprotein was used to study effect of the surface density of nano-segments immobilized on culture dishes on
ex vivo expansion of hematopoietic stem and progenitor cells from umbilical cord blood. It was also used in the separation and cultivation of hematopoietic stem cells from umbilical cord blood by permeation through membranes with nano-segments.
一般的な説明
Lipoprotein, low density (LDL) is synthesized by lipolysis and lipid transfer steps. They are formed from very low-density lipoprotein (VLDL) after uptake by LDL receptor in hepatocytes. LDL normal level of 130 mg/dL is desirable in human plasma. It is referred as bad cholesterol.
Biochem/physiol Actions
LDL and HDL transport both dietary and endogenous cholesterol in the plasma. LDL is the main transporter of cholesterol and cholesteryl esters and makes up more than half of the total lipoprotein in plasma. LDL is absorbed by the liver and other tissues via receptor mediated endocytosis. The cytoplasmic domain of the LDL receptor facilitates the formation of coated pits; receptor-rich regions of the membrane. The ligand binding domain of the receptor recognizes apo-B100 on LDL, resulting in the formation of a clathrin-coated vesicle. ATP-dependent proton pumps lower the pH inside the vesicle resulting dissociation of LDL from its receptor. After loss of the clathrin coat the vesicles fuse with lysozomes, resulting in peptide and cholesteryl ester enzymatic hydrolysis. The LDL receptor can be recycled to the cell membrane. Insulin, tri-iodothyronine and dexamethasome have shown to be involved with the regulation of LDL receptor mediated uptake.
リポタンパク質, 低密度 ヒト血漿由来 上流と下流の製品情報
原材料
準備製品
リポタンパク質, 低密度 ヒト血漿由来 生産企業
Global( 42)Suppliers
- 308068-14-6
- LOW DENSITY LIPOPROTEIN
- LIPOPROTEIN
- LIPOPROTEIN HUMAN
- LIPOPROTEIN, LOW DENSITY
- LIPOPROTEINS, LOW DENSITY, HUMAN
- LIPOPROTEINS, LOW DENSITY, HUMAN PLASMA
- LIPOPROTEIN, LOW DENSITY, HUMAN
- LIPOPROTEIN, LOW DENSITY, HUMAN PLASMA
- LDL
- LDL, HUMAN
- BETA-LIPOPROTEIN
- Lipoprotein, low density from human plasma
- β-Lipoprotein, LDL, Low density lipoprotein
- リポタンパク質, 低密度 ヒト血漿由来