安息香酸カリウム 化学特性,用途語,生産方法
外観
白色～ほとんど白色, 結晶～粉末又は塊
定義
本品は、安息香酸(*)のカリウム塩であり、次の化学式で表される。
参照表示名称：安息香酸
溶解性
水に溶け、エタノール及びアセトンにほとんど溶けない。
用途
ノンアルコール飲料保存剤
用途
保存料等研究用。
化粧品の成分用途
防腐剤
効能
保存剤
説明
Potassium benzoate is the potassium salt of benzoate. It is mostly used for food preservation for inhibiting the growth of mold, yeast and bacteria since it can create low pH condition after entering into the cells to suppress the anaerobic fermentation of glucose. It can also be used in the whistle in many fireworks. In analytic chemistry, it can be used as eluents for ion chromatography to increase the detector response.
化学的特性
Potassium benzoate occurs as a slightly hygroscopic, white, odorless
or nearly odorless crystalline powder or granules. Aqueous
solutions are slightly alkaline and have a sweetish astringent taste.
使用
Pharmaceutic aid (preservative).
調製方法
Potassium benzoate is prepared from the acid–base reaction
between benzoic acid and potassium hydroxide.
応用例（製薬）
Potassium benzoate is predominantly used as an antimicrobial
preservative in a wide range of beverages, foods and some
pharmaceutical formulations. Preservative efficacy increases with
decreasing pH; it is most effective at pH 4.5 or below. However, at
low pH undissociated benzoic acid may produce a slight though
discernible taste in food products.
Increasingly, potassium benzoate is used as an alternative to
sodium benzoate in applications where a low sodium content is
desirable.
Therapeutically, potassium benzoate has also been used in the
management of hypokalemia.
安全性プロファイル
Combustible when
exposed to heat or flame. When heated to
decomposition it emits acrid smoke and
irritating fumes.
安全性
Potassium benzoate is widely used in food products and is generally
regarded as a nontoxic and nonirritant material. However, people
with a history of allergies may show allergic reactions when exposed
to potassium benzoate. Ingestion is inadvisable for asthmatics.
Higher concentrations of potassium benzoate have been reported to
cause irritation to mucous membranes.
The WHO acceptable daily intake of total benzoates including
potassium benzoate, calculated as benzoic acid, has been estimated
at up to 5 mg/kg of body-weight.
貯蔵
Potassium benzoate is stable at room temperature under normal
storage conditions. Since it is slightly hygroscopic, potassium
benzoate should be stored in sealed containers. Exposure to
conditions of high humidity and elevated temperatures should be
avoided.
純化方法
Potassium benzoate [582-25-2] M 160.2. Crystallise it from water (1mL/g) between 100o and 0o. [Beilstein 9 III 375, 9 IV 279.]
不和合性
Potassium benzoate is incompatible with strong acids and strong
oxidizing agents.
規制状況(Regulatory Status)
GRAS listed. Accepted as a food additive in Europe. Included in the
Canadian List of Acceptable Non-medicinal Ingredients.
参考文献
Gjerde, Douglas T., and J. S. Fritz. "Sodium and potassium benzoate and benzoic acid as eluents for ion chromatography." Analytical Chemistry 53.14(1981):2324-2327.
Zengin, N., et al. "The evaluation of the genotoxicity of two food preservatives: Sodium benzoate and potassium benzoate." Food & Chemical Toxicology An International Journal Published for the British Industrial Biological Research Association 49.4(2011):763-9.
Zeb, Alam, et al. "Grape juice preservation with benzoate and sorbate. " Advances in Food Sciences (2009).
Marietta, Michael S. "Fireworks artillery shell." US, US6912958. 2005.
安息香酸カリウム 上流と下流の製品情報
原材料
準備製品