エソメプラゾールマグネシウム三水和物
エソメプラゾールマグネシウム三水和物 物理性質
- 融点 :
- 184-189°C (dec.)
- 貯蔵温度 :
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- 溶解性:
- 水にやや溶けやすく、メタノールに溶けやすく、ヘプタンにほとんど溶けない。
- InChI:
- InChI=1S/2C17H18N3O3S.Mg.H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;/h2*5-8H,9H2,1-4H3;;1H2/q2*-1;+2;
- InChIKey:
- VEVZQDGATGBLIC-UHFFFAOYSA-N
- SMILES:
- C(C1N=CC(C)=C(OC)C=1C)S1C2[N-]C3=CC(OC)=CC=C3N=2[Mg+2]2(O=S(CC3N=CC(C)=C(OC)C=3C)C3[N-]C4=CC(OC)=CC=C4N2=3)O=1.O
- CAS データベース:
- 217087-09-7(CAS DataBase Reference)
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 主な危険性 |
Xn |
|
|
| Rフレーズ |
22 |
|
|
| WGK Germany |
3 |
|
|
| HSコード |
2933399090 |
|
|
| 絵表示（GHS） |
|
| 注意喚起語 |
警告 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
|
P264, P270, P301+P312, P330, P501 |
|
| 注意書き |
|
エソメプラゾールマグネシウム三水和物 価格
もっと(8)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01LKTE7356 |
エソメプラゾールマグネシウム三水和物
Esomeprazole Magnesium Trihydrate |
217087-09-7 |
50mg |
￥17600 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01LKTE7356 |
エソメプラゾールマグネシウム三水和物
Esomeprazole Magnesium Trihydrate |
217087-09-7 |
250mg |
￥61700 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
Y0001028 |
エソメプラゾールマグネシウム 三水和物 European Pharmacopoeia (EP) Reference Standard
Esomeprazole magnesium trihydrate European Pharmacopoeia (EP) Reference Standard |
217087-09-7 |
y0001028 |
￥24700 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
PHR1585 |
Pharmaceutical Secondary Standard; Certified Reference Material
Esomeprazole Magnesium Pharmaceutical Secondary Standard; Certified Reference Material |
217087-09-7 |
1g |
￥24400 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
1249789 |
エソメプラゾールマグネシウム United States Pharmacopeia (USP) Reference Standard
United States Pharmacopeia (USP) Reference Standard |
217087-09-7 |
100MG |
￥78700 |
2024-03-01 |
購入 |
エソメプラゾールマグネシウム三水和物 化学特性,用途語,生産方法
効能
胃酸分泌抑制薬, 消化性潰瘍薬, プロトンポンプ阻害薬
商品名
ネキシウム (アストラゼネカ); ネキシウム (アストラゼネカ)
化学的特性
Off-White Powder
使用
esomeprazole magnesium trihydrate for the healing of peptic ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.
- Zollinger-Ellison syndrome
- Peptic ulcer, site unspecified
- Duodenal ulcer
- Gastric ulcer
- Gastro-oesophageal reflux disease
Esomeprazole belongs to the family of medications known as proton pump inhibitors (PPIs). Esomeprazole is registered by the Therapeutic Goods Administration (TGA) for the following indications:
- Gastro-Oesophageal Reflux Disease (GORD):
- treatment of erosive reflux oesophagitis;
- long-term management of patients with healed oesophagitis to prevent relapse;
- symptomatic treatment of gastro-oesophageal reflux disease (GORD).
In combination with appropriate antibiotics for:
- healing of duodenal ulcer associated with Helicobacter pylori;
- eradication of Helicobacter pylori in patients with active or healed peptic ulcer.
- Short-term treatment of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drug (NSAID) (non-selective and COX-2 selective) therapy.
- Healing of gastric ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.
- Prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy in patients at risk.
brand name
Nexium (AstraZeneca).
生物活性
Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent, orally active H+, K+-ATPase inhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophageal reflux disease research. Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release by inhibiting V-H+-ATPases.
エソメプラゾールマグネシウム三水和物 上流と下流の製品情報
原材料
準備製品
エソメプラゾールマグネシウム三水和物 生産企業
Global( 413)Suppliers
エソメプラゾールマグネシウム三水和物 スペクトルデータ(1HNMR)
217087-09-7(エソメプラゾールマグネシウム三水和物)キーワード:
- 217087-09-7
- ESOMEPRAZOLE MAGNESIUM TRIHYDRATE
- bis(5-methoxy-2-[(s)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1h-benzylimidazole-1-yl) magnesium trihydrate
- (T-4)-Bis[5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]magnesium
- Nexium
- ESOPMEPRAZOLE MG TRIHYDRATE
- 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]benzimidazol-1-ide
- 5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
- 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
- EsoMeprazole Meg. Trihydrate
- Esomeprazole Magnesium (10 mg)
- ESOMEPRAZOLE MAGNESIUM TRIHYDRATE USP
- (S)-OMeprazole MagnesiuM trihydrate
- MagnesiuM,bis[6-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl-kO]-1H-benziMidazolato-kN3]-, hydrate (1:3), (T-4)-
- Esomeprazole magnesium trihydrate
Bis(5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzylimidazole-1-yl) magnesium trihydrate
- Esomeprazole Magnesium (25 mg)
- EsoMeprazole Magnesiu Trihydrate
- Esomeprazole magnesium thihydrate
- Magnesium, bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-, hydrate (1:3), (T-4)-
- Esomeprazole Magnesium Dihydrate/Trihydrate
- Magnesium,bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-kO]-1H-benzimidazolato-kN3]-, hydrate
- Esomeprazole agnesium trihydrate
- Omeprazole Magnesium Trihydrate
- Esomeprazole magnesium trihydrate CRS
- Nesomeprazole magnesium trihydrate
- EsomepazoleTrihydrate
- Esomeprazole Magnesium (1249789)
- Omeprazole(Esomeprazole Magnesium) Trihydrate
- Esomeprazole Magnesium Tri-Hydrate IP/Ph. Eur./BP
- Omeprazole 8.5%/12.5% pellels
- Esomeprzole magnesium Trihydrate
- エソメプラゾールマグネシウム三水和物
- エソメプラゾールマグネシウム 三水和物
- エソメプラゾールマグネシウム水和物
- エソメプラゾールマグネシウム水和物 (JAN)