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ChemicalBook >> CAS DataBase List >> BQ-788

BQ-788

$175 - $5000
Product name: BQ-788
CAS: 156161-89-6
MF: C34H52N5NaO7
MW: 665.81
EINECS:
MDL Number:MFCD00797882
Synonyms:BQ-788 SODIUM;BQ-788 SYNTHETIC >97% ETB ENDOTHELIN REC EPT;N-[(cis-2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucinesodiumsalt;1-ELAIDYLPHOSPHOCHOLINE, >97%;N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl]-1-(methoxycarbonyl)-D-tryptophyl]-D-norleucine sodium salt, 2,6-Dimethylpiperidinecarbonyl-γ-Methyl-Leu-Nin-(Methoxycarbonyl)-D-Trp-D-Nle;N-[N-[N-[(2,6-Dimethyl-1-piperidinyl)carbonyl]-;DMpc-gaMMa-MeLeu-D-Trp(1-CO2CH3)-D-Nle.Na (DMpc : cis-2,6-DiMethylpiperidinocarbonyl);2,6-Dimethylpiperidinecarbonyl-γ-Methyl-Leu-Nin-(Methoxycarbonyl)-D-Trp-D-Nle

Price15 Properties Safety Information Description

15 prices

Selected condition：

Brand

Adipogen Life Sciences
AK Scientific
Alichem
Cayman Chemical
ChemScene
Crysdot
CSNpharm
DC Chemicals
Sigma-Aldrich
TRC

Package

200μg
500μg
1mg
5mg
10mg
100mg
250mg
1g

ManufacturerAdipogen Life Sciences
Product numberAG-CP3-0012-M001
Product descriptionBQ-788.sodiumsalt ≥95%(HPLC)
Packaging1mg
Price$200
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number3506AH
Product descriptionDMPC-Gamma-MELEU-D-Trp(1-Co2CH3)-D-NleNa
Packaging1mg
Price$368
Updated2021-12-16
Buy

ManufacturerAlichem
Product number156161896
Product descriptionSodiumBQ-788
Packaging10mg
Price$400
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number17403
Product descriptionBQ-788 (sodium salt) ≥95%
Packaging500μg
Price$175
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number17403
Product descriptionBQ-788 (sodium salt) ≥95%
Packaging1mg
Price$242
Updated2024-03-01
Buy

ManufacturerChemScene
Product numberCS-2685
Product descriptionBQ-788(sodiumsalt) 98.03%
Packaging1mg
Price$180
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-2685
Product descriptionBQ-788(sodiumsalt) 98.03%
Packaging5mg
Price$420
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-2685
Product descriptionBQ-788(sodiumsalt) 98.03%
Packaging10mg
Price$600
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD31003231
Product descriptionSodiumBQ-788 98+%
Packaging5mg
Price$345
Updated2021-12-16
Buy

ManufacturerCSNpharm
Product numberCSN17348
Product descriptionBQ-788Sodium
Packaging5mg
Price$336
Updated2021-12-16
Buy

ManufacturerDC Chemicals
Product numberDC7542
Product descriptionBQ-788 >98%
Packaging100mg
Price$1250
Updated2021-12-16
Buy

ManufacturerDC Chemicals
Product numberDC7542
Product descriptionBQ-788 >98%
Packaging250mg
Price$2500
Updated2021-12-16
Buy

ManufacturerDC Chemicals
Product numberDC7542
Product descriptionBQ-788 >98%
Packaging1g
Price$5000
Updated2021-12-16
Buy

ManufacturerSigma-Aldrich
Product numberB157
Product descriptionBQ-788 ≥95%,solid
Packaging200μg
Price$231
Updated2024-03-01
Buy

ManufacturerTRC
Product numberB676670
Product descriptionBQ788
Packaging5mg
Price$595
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Adipogen Life Sciences	AG-CP3-0012-M001	BQ-788.sodiumsalt ≥95%(HPLC)	1mg	$200	2021-12-16	Buy
AK Scientific	3506AH	DMPC-Gamma-MELEU-D-Trp(1-Co2CH3)-D-NleNa	1mg	$368	2021-12-16	Buy
Alichem	156161896	SodiumBQ-788	10mg	$400	2021-12-16	Buy
Cayman Chemical	17403	BQ-788 (sodium salt) ≥95%	500μg	$175	2024-03-01	Buy
Cayman Chemical	17403	BQ-788 (sodium salt) ≥95%	1mg	$242	2024-03-01	Buy
ChemScene	CS-2685	BQ-788(sodiumsalt) 98.03%	1mg	$180	2021-12-16	Buy
ChemScene	CS-2685	BQ-788(sodiumsalt) 98.03%	5mg	$420	2021-12-16	Buy
ChemScene	CS-2685	BQ-788(sodiumsalt) 98.03%	10mg	$600	2021-12-16	Buy
Crysdot	CD31003231	SodiumBQ-788 98+%	5mg	$345	2021-12-16	Buy
CSNpharm	CSN17348	BQ-788Sodium	5mg	$336	2021-12-16	Buy
DC Chemicals	DC7542	BQ-788 >98%	100mg	$1250	2021-12-16	Buy
DC Chemicals	DC7542	BQ-788 >98%	250mg	$2500	2021-12-16	Buy
DC Chemicals	DC7542	BQ-788 >98%	1g	$5000	2021-12-16	Buy
Sigma-Aldrich	B157	BQ-788 ≥95%,solid	200μg	$231	2024-03-01	Buy
TRC	B676670	BQ788	5mg	$595	2021-12-16	Buy

Properties

storage temp. :-20°C
solubility :acetonitrile: 0.3 mg/mL
form :solid
color :white

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The endothelin (ET) family of proteins mediate a variety of responses, with ET-1 being a potent and long-lasting constrictor of human cardiovascular vessels. These proteins activate the G protein-coupled receptors ETA and ETB, with ETB being non-specific for ET protein form. BQ-788 is a potent, selective antagonist of ETB (IC50 = 1.2 nM for blocking ET-1 binding to human Girardi heart cells). It weakly inhibits the binding of ET-1 to ETA receptors on human neuroblastoma SK-N-MC cells (IC50 = 1300 nM). BQ-788 competitively antagonizes the vasoconstriction induced by an ETB-selective agonist on isolated rabbit pulmonary arteries, blocks ET-1 induced bronchoconstriction in guinea pigs, and abolishes an ET-1 mediated depressor response in rats.

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