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ChemicalBook >> CAS DataBase List >> Ibudilast

Ibudilast

Ibudilast price.
  • $8 - $1190
  • Product name: Ibudilast
  • CAS: 50847-11-5
  • MF: C14H18N2O
  • MW: 230.31
  • EINECS:637-150-7
  • MDL Number:MFCD00864808
  • Synonyms:IBUDILAST;IBUDILAST-D7;KC-404;1-PROPANONE, 2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL];3-Isobutyryl-2-isopropy-lpyrazolo[1,5-α]pyridine;Ketas;Eyevinal;1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methyl-1-propanone
47 prices
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  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Atlantic Research Chemicals
  • AvaChem
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  • Biosynth Carbosynth
  • Cayman Chemical
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  • 1gm:
  • 50mgs:
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3738-M250
  • Product descriptionIbudilast ≥98%(HPLC)
  • Packaging250mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberC511
  • Product descriptionIbudilast
  • Packaging10mg
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002963
  • Product descriptionIBUDILAST 95.00%
  • Packaging1G
  • Price$975.45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5183
  • Product descriptionIbudilast
  • Packaging5mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5183
  • Product descriptionIbudilast
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5183
  • Product descriptionIbudilast
  • Packaging25mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS475506
  • Product descriptionIbudilast ≥98%
  • Packaging10mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS475506
  • Product descriptionIbudilast ≥98%
  • Packaging50mg
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS475506
  • Product descriptionIbudilast ≥98%
  • Packaging100mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS475506
  • Product descriptionIbudilast ≥98%
  • Packaging250mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS475506
  • Product descriptionIbudilast ≥98%
  • Packaging1g
  • Price$114
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS475506
  • Product descriptionIbudilast ≥98%
  • Packaging5g
  • Price$401
  • Updated2021-12-16
  • Buy
  • ManufacturerAtlantic Research Chemicals
  • Product numberXS100153
  • Product description1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one(Ibudilast) 95%
  • Packaging50mgs:
  • Price$106.04
  • Updated2021-12-16
  • Buy
  • ManufacturerAtlantic Research Chemicals
  • Product numberXS100153
  • Product description1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one(Ibudilast) 95%
  • Packaging1gm:
  • Price$378.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1643
  • Product descriptionIbudilast
  • Packaging5mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1643
  • Product descriptionIbudilast
  • Packaging10mg
  • Price$39
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3738-M250 Ibudilast ≥98%(HPLC) 250mg $240 2021-12-16 Buy
AK Scientific C511 Ibudilast 10mg $42 2021-12-16 Buy
American Custom Chemicals Corporation API0002963 IBUDILAST 95.00% 1G $975.45 2021-12-16 Buy
ApexBio Technology C5183 Ibudilast 5mg $40 2021-12-16 Buy
ApexBio Technology C5183 Ibudilast 10mg $50 2021-12-16 Buy
ApexBio Technology C5183 Ibudilast 25mg $60 2021-12-16 Buy
Arctom AS475506 Ibudilast ≥98% 10mg $8 2021-12-16 Buy
Arctom AS475506 Ibudilast ≥98% 50mg $19 2021-12-16 Buy
Arctom AS475506 Ibudilast ≥98% 100mg $35 2021-12-16 Buy
Arctom AS475506 Ibudilast ≥98% 250mg $55 2021-12-16 Buy
Arctom AS475506 Ibudilast ≥98% 1g $114 2021-12-16 Buy
Arctom AS475506 Ibudilast ≥98% 5g $401 2021-12-16 Buy
Atlantic Research Chemicals XS100153 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one(Ibudilast) 95% 50mgs: $106.04 2021-12-16 Buy
Atlantic Research Chemicals XS100153 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one(Ibudilast) 95% 1gm: $378.2 2021-12-16 Buy
AvaChem 1643 Ibudilast 5mg $29 2021-12-16 Buy
AvaChem 1643 Ibudilast 10mg $39 2021-12-16 Buy

Properties

Melting point :53-54°C
Boiling point :175°C/7.5mmHg(lit.)
Density :1.09
refractive index :1.5500 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: 28 mg/mL, soluble
form :solid
pka :1.22±0.30(Predicted)
color :white
Merck :14,4879
Stability : Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3
InChIKey :ZJVFLBOZORBYFE-UHFFFAOYSA-N
SMILES :C(C1=C2N(N=C1C(C)C)C=CC=C2)(=O)C(C)C
CAS DataBase Reference :50847-11-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Inhibitors of phosphodiesterase 4 (PDE4), which catalyzes the hydrolysis of cAMP, have potential applications in a variety of diseases, including asthma. Ibudilast is an inhibitor of PDE4 (IC50 = 54-239 nM) that, at higher doses, also inhibits PDE3 and PDE5 (IC50 = 1,600-3,510 nM). Through this action, it suppresses the elaboration of mediators involved in asthma and inflammation.

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