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ChemicalBook >> CAS DataBase List >> Levodopa

Levodopa

Levodopa price.
  • $16.8 - $3326.4
  • Product name: Levodopa
  • CAS: 59-92-7
  • MF: C9H11NO4
  • MW: 197.19
  • EINECS:200-445-2
  • MDL Number:MFCD00002598
  • Synonyms:3,4-Dihydroxyphenyl-L-alanine;3,4-L-DIHYDROXYPHENYLALANINE;BETA-(3,4-DIHYDROXYPHENYL)-L-ALANINE;HYDROXYTYROSINE;H-PHE(3,4-DI-HYDROXY)-OH;H-PHE(3,4-DI-OH)-OH;H-TYR(3-HYDROXY)-OH;L-BETA-(3,4-DIHYDROXYPHENYL)ALANINE
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  • Activate Scientific
  • Adipogen Life Sciences
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
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  • Biosynth Carbosynth
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  • ManufacturerActivate Scientific
  • Product numberAS92658
  • Product description3,4-Dihydroxy-L-phenylalanine 95+%
  • Packaging25g
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS92658
  • Product description3,4-Dihydroxy-L-phenylalanine 95+%
  • Packaging100g
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-D0465-G025
  • Product description3,4-Dihydroxy-L-phenylalanine ≥98%
  • Packaging25g
  • Price$71
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-D0465-G100
  • Product description3,4-Dihydroxy-L-phenylalanine ≥98%
  • Packaging100g
  • Price$212
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ90768
  • Product descriptionL-3,4-Dihydrophenylalanine
  • Packaging25g
  • Price$20
  • Updated2021-12-16
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  • ManufacturerAlfa Aesar
  • Product numberA11311
  • Product description3,4-Dihydroxy-L-phenylalanine, 98+%
  • Packaging5g
  • Price$46.2
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA11311
  • Product description3,4-Dihydroxy-L-phenylalanine, 98+%
  • Packaging25g
  • Price$146
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberA11311
  • Product description3,4-Dihydroxy-L-phenylalanine, 98+%
  • Packaging100g
  • Price$471
  • Updated2024-03-01
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045877
  • Product descriptionLEVODOPA 95.00%
  • Packaging5MG
  • Price$550
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045877
  • Product descriptionLEVODOPA 95.00%
  • Packaging10G
  • Price$1166.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0045877
  • Product descriptionLEVODOPA 95.00%
  • Packaging100G
  • Price$3326.4
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8460
  • Product descriptionLevodopa
  • Packaging1g
  • Price$67
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberCFN99800
  • Product descriptionLevodopa ≥98%
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number3015
  • Product descriptionLevodopa
  • Packaging1g
  • Price$30
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number3015
  • Product descriptionLevodopa
  • Packaging5g
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb594069
  • Product descriptionLevodopa
  • Packaging20mg
  • Price$153
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS92658 3,4-Dihydroxy-L-phenylalanine 95+% 25g $25 2021-12-16 Buy
Activate Scientific AS92658 3,4-Dihydroxy-L-phenylalanine 95+% 100g $56 2021-12-16 Buy
Adipogen Life Sciences CDX-D0465-G025 3,4-Dihydroxy-L-phenylalanine ≥98% 25g $71 2021-12-16 Buy
Adipogen Life Sciences CDX-D0465-G100 3,4-Dihydroxy-L-phenylalanine ≥98% 100g $212 2021-12-16 Buy
AK Scientific J90768 L-3,4-Dihydrophenylalanine 25g $20 2021-12-16 Buy
Alfa Aesar A11311 3,4-Dihydroxy-L-phenylalanine, 98+% 5g $46.2 2024-03-01 Buy
Alfa Aesar A11311 3,4-Dihydroxy-L-phenylalanine, 98+% 25g $146 2024-03-01 Buy
Alfa Aesar A11311 3,4-Dihydroxy-L-phenylalanine, 98+% 100g $471 2024-03-01 Buy
American Custom Chemicals Corporation API0045877 LEVODOPA 95.00% 5MG $550 2021-12-16 Buy
American Custom Chemicals Corporation API0045877 LEVODOPA 95.00% 10G $1166.55 2021-12-16 Buy
American Custom Chemicals Corporation API0045877 LEVODOPA 95.00% 100G $3326.4 2021-12-16 Buy
ApexBio Technology A8460 Levodopa 1g $67 2021-12-16 Buy
Arctom CFN99800 Levodopa ≥98% 20mg $30 2021-12-16 Buy
AvaChem 3015 Levodopa 1g $30 2021-12-16 Buy
AvaChem 3015 Levodopa 5g $75 2021-12-16 Buy
Biorbyt Ltd orb594069 Levodopa 20mg $153 2021-12-16 Buy

Properties

Melting point :276-278 °C (lit.)
Boiling point :334.28°C (rough estimate)
alpha :-11.7 º (c=5.3, 1N HCl)
Density :1.3075 (rough estimate)
refractive index :-12 ° (C=5, 1mol/L HCl)
storage temp. :2-8°C
solubility :Slightly soluble in water, practically insoluble in ethanol (96 per cent). It is freely soluble in 1 M hydrochloric acid and sparingly soluble in 0.1 M hydrochloric acid .
pka :2.32(at 25℃)
form :Crystalline Powder
color :White to creamy
Odor :at 100.00 %. odorless
Odor Type :odorless
Water Solubility :Slightly soluble in water, dilute hydrochloric acid and formic acid. Insoluble in ethanol.
Merck :14,5464
BRN :2215169
Stability :Stable. Incompatible with strong oxidizing agents. Light and air sensitive.
InChIKey :WTDRDQBEARUVNC-LURJTMIESA-N
LogP :-1.154 (est)
CAS DataBase Reference :59-92-7(CAS DataBase Reference)
NIST Chemistry Reference :Levodopa(59-92-7)
EPA Substance Registry System :Levodopa (59-92-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dopamine is a neurotransmitter involved in synaptic plasticity, cognition, and the regulation of locomotor control. It is produced endogenously in the substantia nigra and ventral tegmental area but when administered exogenously cannot cross the blood brain barrier. L-DOPA is a metabolic precursor of dopamine that is capable of crossing the blood brain barrier. It is produced from L-tyrosine by trysosine hydroxylase and metabolized by catechol-O-methyl transferase (COMT). In the brain L-DOPA is converted to dopamine. It is conventionally used to increase dopamine concentrations in the brain as a treatment for Parkinson’s disease and stroke recovery. However L-DOPA has a short half-life and is known to elevate homocysteine concentrations in plasma, which can be neurotoxic and induce oxidative damage.

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