S-(-)-7-Desmethyl-8-nitro Blebbistatin
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2物価
選択条件：
ブランド
- 富士フイルム和光純薬株式会社(wako)
パッケージ
- 2.5mg
- 25mg
- 生産者富士フイルム和光純薬株式会社(wako)
- 製品番号W01TRCD422350
- 製品説明
- 英語製品説明S-(-)-7-Desmethyl-8-nitro Blebbistatin
- 包装単位2.5mg
- 価格￥50600
- 更新しました2023-06-01
- 購入
- 生産者富士フイルム和光純薬株式会社(wako)
- 製品番号W01TRCD422350
- 製品説明
- 英語製品説明S-(-)-7-Desmethyl-8-nitro Blebbistatin
- 包装単位25mg
- 価格￥404300
- 更新しました2023-06-01
- 購入
| 生産者 | 製品番号 | 製品説明 | 包装単位 | 価格 | 更新時間 | 購入 |
|---|---|---|---|---|---|---|
| 富士フイルム和光純薬株式会社(wako) | W01TRCD422350 | S-(-)-7-Desmethyl-8-nitro Blebbistatin |
2.5mg | ￥50600 | 2023-06-01 | 購入 |
| 富士フイルム和光純薬株式会社(wako) | W01TRCD422350 | S-(-)-7-Desmethyl-8-nitro Blebbistatin |
25mg | ￥404300 | 2023-06-01 | 購入 |
プロパティ
沸点 :570.7±60.0 °C(Predicted)
比重(密度) :1.51±0.1 g/cm3(Predicted)
貯蔵温度 :Store at -20°C
溶解性 :DMF: 16 mg/ml; DMSO: 16 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
外見 :A crystalline solid
酸解離定数(Pka) :10.02±0.20(Predicted)
比重(密度) :1.51±0.1 g/cm3(Predicted)
貯蔵温度 :Store at -20°C
溶解性 :DMF: 16 mg/ml; DMSO: 16 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
外見 :A crystalline solid
酸解離定数(Pka) :10.02±0.20(Predicted)
安全情報
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説明
(+)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. By rapidly and reversibly inhibiting Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB, it blocks apoptosis-related bleb formation, directed cell migration and cytokinesis in vertebrate cells. However, prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. (S)-nitro-Blebbistatin is an analog of (?)-blebbistatin that is stable to prolonged irradiation at 450-490 nm. This compound, which has the same stereochemistry as the active (?)-blebbistatin isoform, has been successfully used in fluorescent live cell imaging.供給者とメーカー
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