1229208-44-9 Basic information More..
Product Name:Entospletinib (GS-9973)
Synonyms:GS-9973;6-(1H-Indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]imidazo[1,2-a]pyrazin-8-amine;Entospletinib (GS-9973);Entospletinib Dimesylate;GS-9973, Entospletinib;GS-9973;GS 9973;CS-1602;GS9973; GS 9973; ENTOSPLETINIB
CAS:1229208-44-9
MF:C23H21N7O
MW:411.46
EINECS:
Mol File:1229208-44-9.mol
1229208-44-9

Use

Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM in a cell-free assay and showed 13-to >1000-fold cellular selectivity for Syk over other kinases(including Jak2, ckit, Flt3, Ret, KDR) as assessed by target protein phosphorylation or functional response.

Entospletinib (GS-9973) manufacturers

  • Entospletinib (GS-9973)
  • US $6.68 / KG
  • 2020-01-09
  • CAS:1229208-44-9
  • Min. Order: 1KG
  • Purity: 97%-99%
  • Supply Ability: 1kg-1000kg
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