| | 10540-29-1 Basic information More.. |
| Product Name: | Tamoxifen | | Synonyms: | (Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene, trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine;2-[4-[(Z)-1,2-Di(phenyl)but-1-enyl]phenoxy]-N,N-dimethylethanamine;2-[4-[(Z)-1,2-Diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine;2-[p-[(Z)-1,2-Diphenyl-1-butenyl]phenyloxy]-N,N-dimethylethanamine;N,N-Dimethyl-2-[p-[(Z)-1,2-diphenyl-1-butenyl]phenoxy]ethanamine;C07108;Tamoxifen,(Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene, trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine;1-p-β-DiMethylaMinoethoxyphenyl-trans-1,2-diphenylbut-1-ene | | CAS: | 10540-29-1 | | MF: | C26H29NO | | MW: | 371.51 | | EINECS: | 234-118-0 | | Mol File: | 10540-29-1.mol |  |
Use
Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen
(4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF
production in breast tumor cells.
Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response mo
difiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
- Tamoxifen Citrate
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- US $1.00 / g
- 2024-04-25
- CAS:10540-29-1
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 20tons
- Tamoxifen
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- US $100.00 / kg
- 2024-04-25
- CAS:10540-29-1
- Min. Order: 1kg
- Purity: 99.9%
- Supply Ability: 20tons
- Tamoxifen
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- US $3.00-865.00 / g
- 2024-04-25
- CAS:10540-29-1
- Min. Order: 1g
- Purity: 99.99%
- Supply Ability: 1000kg
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10540-29-1
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