Exendin-3 (9-39) amide manufacturers
- Exendin-3 (9-39) amide
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- $9.90 / 1KG
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2021-11-13
- CAS:133514-43-9
- Min. Order: 100KG
- Purity: 99%
- Supply Ability: 10 tons
- Exendin-3 (9-39) amide
-
- $9.90 / 1KG
-
2021-11-12
- CAS:133514-43-9
- Min. Order: 100KG
- Purity: 99%
- Supply Ability: 10 tons
- Exendin (9-39)
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- $1.00 / 5MG
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2018-07-30
- CAS:133514-43-9
- Min. Order: 5MG
- Purity: >95%
- Supply Ability: 5mg,10mg,25mg,100mg,1g,10g
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| Exendin-3 (9-39) amide Basic information |
| Exendin-3 (9-39) amide Chemical Properties |
density | 1.51 | RTECS | LF2460000 | storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | solubility | H2O : 50 mg/mL (14.84 mM; Need ultrasonic) | form | Solid | Water Solubility | Soluble in water at 1mg/ml | InChIKey | WSEVKKHALHSUMB-UHFFFAOYSA-N |
| Exendin-3 (9-39) amide Usage And Synthesis |
Description | Exendin-3 (9-39) amide is a truncated form of the exendin-4 peptide that acts as a potent competitive antagonist for the glucagon-like peptide 1 receptor (GLP-1R; Kd = 1.7 nM in CHL cells transfected with cloned human GLP-1). It inhibits exendin-3-induced increases in cAMP levels in guinea pig pancreas cells (IC50 = 20 nM). Exendin-3 (9-39) amide administration in the hypothalamus (10 and 100 μg, i.c.v.) reverses GLP-1 inhibition of feeding behavior in rats. | Uses | Exendin-3 (9-39) is a potent and selective GLP-1 receptor antagonist. | Uses | Biological probe. | General Description | Exendin Fragment 9-39 is an antagonist of glucagon-like peptide-1 (GLP-1) receptor, and also acts as an inhibitor of glucosedependent insulinotropic polypeptide (GIP)-receptor binding. It also prevents the production of cAMP by GIP. GLP-1, along with GIP, acts as a physiological incretin. | Biochem/physiol Actions | GLP-1 (glucagon-like peptide-1) receptor antagonist. Competitive inhibitor of exendin-3 and exendin-4. | storage | Store at -20°C |
| Exendin-3 (9-39) amide Preparation Products And Raw materials |
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