(S)-Modafinil

(S)-Modafinil Basic information

Product Name:	(S)-Modafinil
Synonyms:	(S)-(+)-Modafinil;(S)-Modafinil;2-[(S)-(Diphenylmethyl)sulfinyl]acetamide;CRL 40983;AcetaMide, 2-[(S)- (diphenylMethyl)sulfinyl]-;Acetamide,2-[(S)-(diphenylmethyl)sulfinyl]- (Related Reference);YFGHCGITMMYXAQ-IBGZPJMESA-N;Modafinil S-Isomer
CAS:	112111-47-4
MF:	C15H15NO2S
MW:	273.35
EINECS:
Product Categories:	Chiral Reagents;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals
Mol File:	112111-47-4.mol

(S)-Modafinil Chemical Properties

Melting point	157-159°C
Boiling point	559.1±50.0 °C(Predicted)
density	1.283±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 0.25 mg/ml
form	A crystalline solid
pka	14.88±0.40(Predicted)
CAS DataBase Reference	112111-47-4

Safety Information

MSDS Information

(S)-Modafinil Usage And Synthesis

Chemical Properties	White Solid
Uses	Used for treatment of excessive sleepiness, α1-adrenoceptor agonist.
Uses	(S)-Modafinil is Used for treatment of excessive sleepiness, it is a1-adrenoceptor agonist.
Definition	ChEBI: (S)-modafinil is a 2-[(diphenylmethyl)sulfinyl]acetamide that has S configuration at the sulfur atom. The racemate comprising (S)-modafinil and its enantiomer, armodafinil, is known as modafinil and is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The enantiomers have similar pharmacological actions in animals. It has a role as a central nervous system stimulant and a eugeroic. It is an enantiomer of an armodafinil.

(S)-Modafinil Preparation Products And Raw materials

Tag:(S)-Modafinil(112111-47-4) Related Product Information

Modafinil Carboxylate Methyl Ester QARQPIWTMBRJFX-DYVTXVBDSA-N (R)-(-)-Modafinil Acid Modafinil-d5 Sulfone 2-Benzhydrylsulphinylacetic acid BisfluoroModafinil Armodafinil 2-[(Diphenylmethyl)sulfonyl] Acetamide Naratriptan (S)-Modafinil Modafinil 2-[(Diphenylmethyl)thio]acetamide

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