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Mainchem Co., Ltd.
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Product Name:4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT
CAS:15220-11-8
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| Company Name: |
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:4-Methylumbelliferyl sulfate potassium salt, 99%
CAS:15220-11-8
Purity:99% Package:1G;5G
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| | 4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT Basic information |
| | 4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT Chemical Properties |
| | 4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT Usage And Synthesis |
| Chemical Properties | Crystalline Solid | | Uses | Met-enkephalin analog found in opioid extracts of brain and adrenal chromaffin cells that is an artifact generated by trichloroacetic acid extraction. MUS is used as a fluorimetric substrate for arylsulphatase enzyme. Subsitution of the hydroxyl group of 4-Methylumbelliferyl sulfate potassium salt causes the excitation wavelength of the umbelliferone to shift to shorter values and also brings about a decrease in fluorescence. Fluorescence: max. Abs = 334 mm; max. Em. = 370 mm | | Uses | 4-Methylumbelliferyl sulfate potassium salt is a fluorometric substrate for the determination of sulfatase. This substrate has been used in the discovery of tyrosine sulfotransferase inhibitors, particularly in P-selectin glycoprotein ligand-1 binding. This compound is virtually non-fluorescent until cleavage by sulfatase enzymes, then emits blue fluorescence (450 nm) with excitation at 360 nm. Use of this compound in high-throughput fluorescence based screening led to the discovery of several potent beta-arylsulfotransferase IV (beta-AST-IV) inhibitors. |
| | 4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT Preparation Products And Raw materials |
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