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L-Malic acid

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Company Name: Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd
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Products Intro: Product Name:L-Malic Acid
CAS:97-67-6
Purity:99% Package:5KG;25KG
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Products Intro: Product Name: L-Malic acid
CAS:97-67-6
Purity:99% Package:1KG;6USD|25KG;5USD|100KG;1USD

L-Malic acid manufacturers

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  • 2024-04-23
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L-Malic acid Basic information
Product Name:L-Malic acid
Synonyms:L(-)-Malic acid, 30 wt% aqueous solution;Butanedioic acid, hydroxy-, (2S)-;L-MALIC ACID L;L-LYSINEMONOHCL;L-MALIC ACID / (S)-(-)-HYDROXYSUCCINIC ACID;(S)-(-)-2-Hydroxysuccinic acid, L-Hydroxybutanedioic acid;S-2-Hydroxybutanedioic acid;)-Malic ac
CAS:97-67-6
MF:C4H6O5
MW:134.09
EINECS:202-601-5
Product Categories:Plant extracts;Aliphatics;Chiral Reagents;Chiral chemicals;MalicAcidSeries;Carboxylic Acids (Chiral);Chiral Building Blocks;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Food & Feed ADDITIVES;Food additive and acidulant;Imidazoles ,Heterocyclic Acids;bc0001;97-67-6
Mol File:97-67-6.mol
L-Malic acid Structure
L-Malic acid Chemical Properties
Melting point 101-103 °C (lit.)
Boiling point 167.16°C (rough estimate)
alpha -2 º (c=8.5, H2O)
density 1.60
vapor pressure 0Pa at 25℃
FEMA 2655 | L-MALIC ACID
refractive index -6.5 ° (C=10, Acetone)
Fp 220 °C
storage temp. Store below +30°C.
solubility H2O: 0.5 M at 20 °C, clear, colorless
form Powder
Specific Gravity1.595 (20/4℃)
color White
PH2.2 (10g/l, H2O, 20℃)
pka(1) 3.46, (2) 5.10(at 25℃)
Odorodorless
Odor Typeodorless
optical activity[α]20/D 30±2°, c = 5.5% in pyridine
Water Solubility soluble
JECFA Number619
Merck 14,5707
BRN 1723541
InChIKeyBJEPYKJPYRNKOW-REOHCLBHSA-N
LogP-1.68
CAS DataBase Reference97-67-6(CAS DataBase Reference)
NIST Chemistry ReferenceButanedioic acid, hydroxy-, (s)-(97-67-6)
EPA Substance Registry SystemButanedioic acid, 2-hydroxy-, (2S)- (97-67-6)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS ON7175000
TSCA Yes
HS Code 29181980
MSDS Information
ProviderLanguage
L(-)-Malic acid English
SigmaAldrich English
ACROS English
ALFA English
L-Malic acid Usage And Synthesis
DescriptionL-Malic acid is nearly odorless (sometimes a faint, acrid odor) with a tart, acidic taste. It is nonpungent. May be prepared by hydration of maleic acid; by fermentation from sugars.
Chemical PropertiesL-Malic acid is nearly odorless (sometimes a faint, acrid odor). This compound has a tart, acidic, nonpungent taste.
Chemical Propertiesclear colourless solution
OccurrenceOccurs in maple sap, apple, melon, papaya, beer, grape wine, cocoa, sake, kiwifruit and chicory root.
UsesThe naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece
UsesL-Malic acid is used as a food additive, Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
UsesIntermediate in chemical synthesis. Chelating and buffering agent. Flavoring agent, flavor enhancer and acidulant in foods.
PreparationL-Malic acid can be prepared by hydration of maleic acid; by fermentation from sugar.
DefinitionChEBI: An optically active form of malic acid having (S)-configuration.
General DescriptionL-Malic acid is an organic acid that is commonly found in wine. It plays an important role in wine microbiological stability.
Biochem/physiol ActionsL-Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. L-Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.
Purification MethodsCrystallise S-malic acid (charcoal) from ethyl acetate/pet ether (b 55-56o), keeping the temperature below 65o. Or dissolve it by refluxing in fifteen parts of anhydrous diethyl ether, decant, concentrate to one-third volume and crystallise it at 0o, repeatedly to constant melting point. [Beilstein 3 IV 1123.]
Tag:L-Malic acid(97-67-6) Related Product Information
Citric acid Dimethyl succinate Ethyl 2-(Chlorosulfonyl)acetate meso-2,3-Dibromosuccinic acid Disodium succinate D(-)-Tartaric acid Folic acid DL-Malic acid Ammonium succinate Succinic acid Glycine D(+)-Malic acid Ascoric Acid Oxobutanedioic acid 3,4-dihydroxybutanoic acid Malic acid 4-Me ester 2-HYDROXYSUCCINIC ACID METHYL ESTER L-Carnosine