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Metandienone

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Company Name:Wuhan Fortuna Chemical Co., Ltd  Gold
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Metandienone Basic information
Outline Traits Pharmacological effects Uses Dosage Dosage Adverse reactions Contraindications Precautions Drug Interactions Dosage forms Uses
Product Name:Metandienone
Synonyms:1,2-Dehydro-17-methyltestosterone;17-alpha-methyl-17-beta-hydroxy-1,4-androstadien-3-one;17alpha-methyl-17beta-hydroxyandrosta-1,4-dien-3-one;17alpha-Methyl-1-dehydrotestosterone;17beta-Hydroxy-17alpha-methylandrosta-1,4-dien-3-one;17-beta-hydroxy-17-alpha-methyl-androsta-4-dien-3-one;17-beta-Hydroxy-17-alpha-methylandrostra-1,4-dien-3-one;17-beta-hydroxy-17-methyl-androsta-4-dien-3-one
CAS:72-63-9
MF:C20H28O2
MW:300.43512
EINECS:200-787-2
Product Categories:Biochemistry;Hydroxyketosteroids;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;Finished Steroid and Hormone;API
Mol File:72-63-9.mol
Metandienone Structure
Metandienone Chemical Properties
mp 165-166 °C
storage temp. 2-8°C
Merck 5951
CAS DataBase Reference72-63-9(CAS DataBase Reference)
NIST Chemistry ReferenceMethandrostenolone(72-63-9)
Safety Information
Hazard Codes F,T
Risk Statements 60-61-11-19-38
Safety Statements 53-45
RIDADR 3249
WGK Germany 3
RTECS BV8000000
8
HazardClass 6.1(b)
PackingGroup III
HS Code 29329970
Hazardous Substances Data72-63-9(Hazardous Substances Data)
MSDS Information
ProviderLanguage
Metandienone English
Metandienone Usage And Synthesis
OutlineThe metandienone is the de-hydrogenation derivative of methyl-testosterone with a similar protein anabolic effect as testosterone propionate but with its effect of male hormone being weak (about one per cent of the latter one). This product can promote the protein synthesis, inhibit the protein hetero-plasia and maintain the balance of positive nitrogen, thus enabling the increase of the appetite, the growth of the muscle and weight gain; it can promote the deposit of calcium and phosphorus in the bone tissue, promote the formation of bone cell mesenchyme, accelerate the bone calcification and bone growth; promote angiogenesis and granulation tissue formation, accelerate the wound repair. It can reduce blood cholesterol and improve the lipid metabolism.
Metandienone has been abused in US sports competition. However, because of the side effects of the male hormone, long-term or large doses are very harmful to the body and therefore, it had been included in the disabled stimulants list of the International Olympic Committee in 1976.There are in total of 31 species of disabled anabolic agents: metenolone, methandriol, boldenone, methyltestosterone, clenbuterol, mibolerone, clostebol, nandrolone, danazol, 19-nor-androstenedione diol, dehydrochlormethyltestosterone, 19-Nor-4-androstene-3, 17-dione, diethyl nandrolone, hydroxyl-methyl androsterone, oxandrolone, fluoro-1-methyl testosterone, hydroxymethyl testosterone, formebolone, oxymetholone, gestrinone, mesterolone, stanozolol, dianabol, and trenbolone.
TraitsMetandienone is white or white crystalline powder and is odorless. It is insoluble in water but soluble in alcohol, chloroform and slightly soluble in ether.
the chemical formula of metandienone
Figure 1 is the chemical formula of metandienone
Pharmacological effects1. It can promote protein synthesis, inhibit the protein hetero-plasia, maintain the balance of positive nitrogen, and thus enabling the increase of appetite, muscle growth and weight gain.
2. It can promote the deposition of calcium and phosphorus in bone tissue, promote the formation of bone cell mesenchyme, and accelerate the bone calcification and bone growth.
3. It can promote the renascence of the tissue and formation of granulation and accelerate the repair of wounds and ulcers.
4. It can reduce the blood cholesterol and improve lipid metabolism.
UsesIt is suitable for treating lack of protein synthesis and increased decomposition, such as the negative nitrogen balance caused by chronic wasting disease, severe infection, trauma and burns, cancer, osteoporosis, children mal-development, dwarfism, bone fracture which is not easy for healing and high cholesterol symptom.
DosageFor adult, at the beginning, take 10 ~ 30mg daily and separate into 2 to 3 times for oral administration. After the control of the disease, you can change and maintain a daily 5 ~ 10mg with continuous administration of 4 to 8 weeks being one treatment course. The interval of repeating the treatment course should be 1-2 months. Elderly should reduce the dosage according to the exact condition. Infants should take 0.05mg / kg per day. In order to improve the efficacy, the patients should also simultaneously administer appropriate amount of protein, sugar and vitamins.
DosageFor adult, at the beginning, take 10 ~ 30mg daily and separate into 2 to 3 times for oral administration. After the control of the disease, you can change and maintain a daily 5 ~ 10mg with continuous administration of 4 to 8 weeks being one treatment course. The interval of repeating the treatment course should be 1-2 months. Elderly should reduce the dosage according to the exact condition. Infants should take 0.05mg / kg per day. In order to improve the efficacy, the patients should also simultaneously administer appropriate amount of protein, sugar and vitamins.
Adverse reactions1 The adverse reactions of metandienone are similar as those of general androgens and anabolic steroids. The patients may get gastrointestinal reactions such as nausea, vomiting, indigestion, and diarrhea. Long-term large-scale use can cause bone weight gain, sodium retention, increased blood supply to the skin, hypocalcemia and bone hyperplasia. For female patients, there may be slight masculine reactions such as acne, hirsutism, thicker sound, clitoral hypertrophy and menstrual disorders.
2. Side effects on the liver such as jaundice, liver dysfunction etc. There have also been reports about the liver cancer and benign hepatocellular adenoma after the application of metandienone.
Contraindications1. Patients allergic to this product should be disabled.
2. Patients of liver dysfunction should be disabled.
3. Pregnant or patients may become pregnant during treatment should be disabled.
4. Patients suspected of getting prostate cancer, kidney disease, hypertension and prostatic hypertrophy should be disabled.
Precautions1.The liver function should be monitored during the process of treatment with metandienone.
2. The dose of the elderly should be reduced.
3. In order to improve the efficacy, it is recommended for the patients to take appropriate amount of protein, sugar and vitamin at the same time.
Drug InteractionsUpon simultaneously application of both hydroxy phenylbutazone metandienone, the plasma concentrations of the hydroxyl phenylbutazone may be increased.
Dosage formsTablets: Each tablet 1mg, 2.5mg, 5mg.
UsesIt can be should as medicines of androgens and anabolic hormones.
It can be used for treating expendable chronic disease, children mal-development, osteoporosis and hyperlipidemia.
Chemical PropertiesWhite Solid
UsageAnabolic steroid. Androgen. Controlled substance.
Metandienone Preparation Products And Raw materials
Tag:Metandienone(72-63-9) Related Product Information
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