|Company Name:||INTATRADE GmbH |
|Metandienone Chemical Properties|
|Metandienone Usage And Synthesis|
|Outline||The metandienone is the de-hydrogenation derivative of methyl-testosterone with a similar protein anabolic effect as testosterone propionate but with its effect of male hormone being weak (about one per cent of the latter one). This product can promote the protein synthesis, inhibit the protein hetero-plasia and maintain the balance of positive nitrogen, thus enabling the increase of the appetite, the growth of the muscle and weight gain; it can promote the deposit of calcium and phosphorus in the bone tissue, promote the formation of bone cell mesenchyme, accelerate the bone calcification and bone growth; promote angiogenesis and granulation tissue formation, accelerate the wound repair. It can reduce blood cholesterol and improve the lipid metabolism. |
Metandienone has been abused in US sports competition. However, because of the side effects of the male hormone, long-term or large doses are very harmful to the body and therefore, it had been included in the disabled stimulants list of the International Olympic Committee in 1976.There are in total of 31 species of disabled anabolic agents: metenolone, methandriol, boldenone, methyltestosterone, clenbuterol, mibolerone, clostebol, nandrolone, danazol, 19-nor-androstenedione diol, dehydrochlormethyltestosterone, 19-Nor-4-androstene-3, 17-dione, diethyl nandrolone, hydroxyl-methyl androsterone, oxandrolone, fluoro-1-methyl testosterone, hydroxymethyl testosterone, formebolone, oxymetholone, gestrinone, mesterolone, stanozolol, dianabol, and trenbolone.
|Traits||Metandienone is white or white crystalline powder and is odorless. It is insoluble in water but soluble in alcohol, chloroform and slightly soluble in ether. |
Figure 1 is the chemical formula of metandienone
|Pharmacological effects||1. It can promote protein synthesis, inhibit the protein hetero-plasia, maintain the balance of positive nitrogen, and thus enabling the increase of appetite, muscle growth and weight gain. |
2. It can promote the deposition of calcium and phosphorus in bone tissue, promote the formation of bone cell mesenchyme, and accelerate the bone calcification and bone growth.
3. It can promote the renascence of the tissue and formation of granulation and accelerate the repair of wounds and ulcers.
4. It can reduce the blood cholesterol and improve lipid metabolism.
|Uses||It is suitable for treating lack of protein synthesis and increased decomposition, such as the negative nitrogen balance caused by chronic wasting disease, severe infection, trauma and burns, cancer, osteoporosis, children mal-development, dwarfism, bone fracture which is not easy for healing and high cholesterol symptom.
|Dosage||For adult, at the beginning, take 10 ~ 30mg daily and separate into 2 to 3 times for oral administration. After the control of the disease, you can change and maintain a daily 5 ~ 10mg with continuous administration of 4 to 8 weeks being one treatment course. The interval of repeating the treatment course should be 1-2 months. Elderly should reduce the dosage according to the exact condition. Infants should take 0.05mg / kg per day. In order to improve the efficacy, the patients should also simultaneously administer appropriate amount of protein, sugar and vitamins.
|Dosage||For adult, at the beginning, take 10 ~ 30mg daily and separate into 2 to 3 times for oral administration. After the control of the disease, you can change and maintain a daily 5 ~ 10mg with continuous administration of 4 to 8 weeks being one treatment course. The interval of repeating the treatment course should be 1-2 months. Elderly should reduce the dosage according to the exact condition. Infants should take 0.05mg / kg per day. In order to improve the efficacy, the patients should also simultaneously administer appropriate amount of protein, sugar and vitamins. |
|Adverse reactions||1 The adverse reactions of metandienone are similar as those of general androgens and anabolic steroids. The patients may get gastrointestinal reactions such as nausea, vomiting, indigestion, and diarrhea. Long-term large-scale use can cause bone weight gain, sodium retention, increased blood supply to the skin, hypocalcemia and bone hyperplasia. For female patients, there may be slight masculine reactions such as acne, hirsutism, thicker sound, clitoral hypertrophy and menstrual disorders. |
2. Side effects on the liver such as jaundice, liver dysfunction etc. There have also been reports about the liver cancer and benign hepatocellular adenoma after the application of metandienone.
|Contraindications||1. Patients allergic to this product should be disabled. |
2. Patients of liver dysfunction should be disabled.
3. Pregnant or patients may become pregnant during treatment should be disabled.
4. Patients suspected of getting prostate cancer, kidney disease, hypertension and prostatic hypertrophy should be disabled.
|Precautions||1.The liver function should be monitored during the process of treatment with metandienone. |
2. The dose of the elderly should be reduced.
3. In order to improve the efficacy, it is recommended for the patients to take appropriate amount of protein, sugar and vitamin at the same time.
|Drug Interactions||Upon simultaneously application of both hydroxy phenylbutazone metandienone, the plasma concentrations of the hydroxyl phenylbutazone may be increased.
|Dosage forms||Tablets: Each tablet 1mg, 2.5mg, 5mg.
|Uses||It can be should as medicines of androgens and anabolic hormones. |
It can be used for treating expendable chronic disease, children mal-development, osteoporosis and hyperlipidemia.
|Chemical Properties||White Solid|
|Usage||Anabolic steroid. Androgen.
|Metandienone Preparation Products And Raw materials|