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| | Rimantadine hydrochloride Basic information |
| | Rimantadine hydrochloride Chemical Properties |
| Melting point | >300 °C(lit.) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly), Water(Slightly) | | form | Solid | | color | White to Off-White | | Water Solubility | Freely soluble in water. | | Merck | 14,8224 | | InChI | InChI=1S/C12H21N.ClH/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12;/h8-11H,2-7,13H2,1H3;1H | | InChIKey | OZBDFBJXRJWNAV-UHFFFAOYSA-N | | SMILES | C1C2CC3(C(N)C)CC1CC(C3)C2.Cl | | CAS DataBase Reference | 1501-84-4 |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | AU4717000 | | HS Code | 29213000 | | Toxicity | LD50 oral in rat: 640mg/kg |
| | Rimantadine hydrochloride Usage And Synthesis |
| Description | Rimantadine hydrochloride is an antiviral analogue of amantadine, reportedly useful in the
prophylaxis and treatment of influenza A. Compared with amantadine, nmantadine
appears to have a lower side-effect profile. | | Chemical Properties | White Crystalline Solid | | Originator | DuPont (USA) | | Uses | Rimantadine Hydrochloride is used as an antiviral agent. | | Definition | ChEBI: Rimantadine hydrochloride is an organic molecular entity. | | Brand name | Flumadine (Forest);Roflual. | | references | [1] koff w c, elm jr j l, halstead s b. suppression of dengue virus replication in vitro by rimantadine hydrochloride[j]. the american journal of tropical medicine and hygiene, 1981, 30(1): 184-189.
[2] koff w c, peavy d l, knight v. inhibition of in vitro proliferative responses of human lymphocytes by rimantadine hydrochloride[j]. infection and immunity, 1979, 23(3): 665-669.
[3] hayden f g, monto a s. oral rimantadine hydrochloride therapy of influenza a virus h3n2 subtype infection in adults[j]. antimicrobial agents and chemotherapy, 1986, 29(2): 339-341. |
| | Rimantadine hydrochloride Preparation Products And Raw materials |
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