- Pentoxyverine
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- $0.00 / 1KG
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2024-03-16
- CAS:77-23-6
- Min. Order: 100g
- Purity: 98%+
- Supply Ability: 100kg
- Pentoxyverine Citrite
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- $0.00 / 1Kg/Bag
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2021-11-24
- CAS:77-23-6
- Min. Order: 1KG
- Purity: 99%min
- Supply Ability: 1000KG
- Pentoxyverine
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- $15.00 / 1KG
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2021-07-10
- CAS:77-23-6
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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| | Pentoxyverine Basic information |
| Product Name: | Pentoxyverine | | Synonyms: | 1-phenyl-1-cyclopentanecarboxylate;1-Phenylcyclopentane-1-Carboxylic acid diethylaminoethoxyethyl ester;1-phenylcyclopentane-1-carboxylicaciddiethylaminoethoxyethylester;1-phenyl-cyclopentanecarboxylicaci2-(2-(diethylamino)ethoxy)ethylester;1-phenylcyclopentanecarboxylicacid2-(2-diethylaminoethoxy)ethylester;ucb2543;CARETAPENTANE;Carbetapentane (base and/or unspecified salts) | | CAS: | 77-23-6 | | MF: | C20H31NO3 | | MW: | 333.46 | | EINECS: | 201-014-1 | | Product Categories: | Miscellaneous Biochemicals | | Mol File: | 77-23-6.mol |  |
| | Pentoxyverine Chemical Properties |
| | Pentoxyverine Usage And Synthesis |
| Originator | Asthma ,Nichiiko | | Uses | Carbetapentane is an antitussive anticonvulsant sigma site agonist. | | Definition | ChEBI: 1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester is a member of benzenes. | | Manufacturing Process | 1-Phenylcyclopentane carbonitrile was obtained by treatment of phenylacetonitrile with sodium amide and 1,4-dibrombutane.
1-Phenyl-1-cyclopentane carboxylic acid was produced in the result of reaction of 1-phenylcyclopentane carbonitrile with sulfuric acid.
1-Phenyl-1-cyclopentanecarbonyl chloride was obtained by treatment of 1phenyl-1-cyclopentane carboxylic acid with thionyl chloride.
A mixture of 0.5 mol of 1-phenyl-1-cyclopentanecarbonyl chloride and of 0.5 mol of 2-(2-diethylaminoethoxy)ethanol (herein-after referred to as the amino alcohol) in 300 ml of toluene is heated under reflux for 20 h. The mixture is thereafter made alkaline by means of an aqueous solution of caustic soda and decanted; the toluenic layer is washed with water and concentrated in vacuo. The residue is distilled under high vacuum. After two fractional distillations, the 2-(2-diethylaminoethoxy)ethyl 1-phenylcyclopentane-carboxylate is obtained, in 85% yield. Boiling point 164°C/0.1 mm. Hg. | | Brand name | Toclase (Pfizer). | | Therapeutic Function | Antitussive |
| | Pentoxyverine Preparation Products And Raw materials |
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