| Company Name: |
Varanous Labs Pvt Ltd
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| Tel: |
+91-7036248882 +91-7036248882 |
| Email: |
bheemashankar.e@varanouslabs.com |
| Products Intro: |
Product Name:O-Desmethyl galantamine
CAS:60755-80-8
Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:O-DesMethyl GalanthaMine
CAS:60755-80-8
Package:50Mg,5Mg
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| | O-DESMETHYLGALANTHAMINE Basic information |
| Product Name: | O-DESMETHYLGALANTHAMINE | | Synonyms: | (4aS,6R,8aS)-4a,5,9,10,11,12-Hexahydro-11-Methyl-6H-benzofuro[3a,3,2-ef][2]benzazepine-3,6-diol;(4aS,8aS)-11-Methyl-4aα,5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzoazepine-3,6β-diol;(8aS)-5,6,9,10,11,12-Hexahydro-11-methyl-4aαH-benzofuro[3a,3,2-ef][2]benzazepine-3,6β-diol;6-O-Demethylgalanthamine;10-Methyl-galantham-1-ene-3b,6-diol;O-Demethyl-galanthamine;Sanguinine;10-Methyl-galantham-1-ene-3,6-diol | | CAS: | 60755-80-8 | | MF: | C16H19NO3 | | MW: | 273.33 | | EINECS: | | | Product Categories: | Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals | | Mol File: | 60755-80-8.mol |  |
| | O-DESMETHYLGALANTHAMINE Chemical Properties |
| Melting point | 227-230°C (dec.) | | Boiling point | 451.9±45.0 °C(Predicted) | | density | 1.37±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | DMSO: soluble | | form | A solid | | pka | 9.39±0.40(Predicted) | | CAS DataBase Reference | 60755-80-8 |
| | O-DESMETHYLGALANTHAMINE Usage And Synthesis |
| Chemical Properties | Pale Yellow Powder | | Uses | Sanguinine has a more potent acetylcholinesterase inhibitory activity than galanthamine due to an extra hydroxyl group available for potential interaction with acetylcholinesterase. Sanguinine, in turn, is 10-fold more selective than galanthamine for acetylcholinesterase (AChE) vs. butyrylcholinesterase (BuChE). The lack of AChE inhibitory activity of lycoramine and epinorlicoramine could be due to the occurrence of a double bond in ring C, which does not allow these alkaloids to have the same spatial configuration as the active alkaloids of this series. | | Uses | A metabolite of Galanthamine (G188500), a selective acetylcholinesterase inhibitor. | | Uses | A metabolite of Galanthamine, a selective acetylcholinesterase inhibitor | | Definition | ChEBI: Sanguinine is a benzazepine. |
| | O-DESMETHYLGALANTHAMINE Preparation Products And Raw materials |
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