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| | N,N,N',N'-Tetramethyl-1,4-phenylenediamine Basic information |
| Product Name: | N,N,N',N'-Tetramethyl-1,4-phenylenediamine | | Synonyms: | N,N,N',N'-TETRAMETHYL-1,4-PHENYLENEDIAMINE;N,N,N',N'-TETRAMETHYL-P-PHENYLENEDIAMINE;1,4-BIS(DIMETHYLAMINO)BENZENE;1,4-bis(dimethylamino)-benzen;4-Benzenediamine,N,N,N’,N’-tetramethyl-1;Benzene, 1,4-bis(dimethylamino)-;N,N,N',N'-Tetramethyl-1,4-Benzenediamine;N,N,N',N'-Tetramethyl-p-fenylendiamin | | CAS: | 100-22-1 | | MF: | C10H16N2 | | MW: | 164.25 | | EINECS: | 202-831-6 | | Product Categories: | | | Mol File: | 100-22-1.mol |  |
| | N,N,N',N'-Tetramethyl-1,4-phenylenediamine Chemical Properties |
| Melting point | 49-51 °C(lit.) | | Boiling point | 260 °C(lit.) | | density | 0.9743 (rough estimate) | | refractive index | 1.5700 (estimate) | | Fp | >230 °F | | storage temp. | Store below +30°C. | | form | powder | | pka | 5.92±0.12(Predicted) | | color | off-white to gray | | Water Solubility | slightly in cold, more in hot water | | Sensitive | Air & Light Sensitive | | Merck | 14,9228 | | BRN | 1564025 | | Stability: | Stable, but may be air or light sensitive. Combustible. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents. | | CAS DataBase Reference | 100-22-1(CAS DataBase Reference) | | NIST Chemistry Reference | 1,4-Benzenediamine, N,N,N',N'-tetramethyl-(100-22-1) | | EPA Substance Registry System | N,N,N',N'-Tetramethyl-p-phenylenediamine (100-22-1) |
| Hazard Codes | Xn | | Risk Statements | 20/21/22-40-36/37/38 | | Safety Statements | 28-28A-36-26-22 | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 1 | | RTECS | ST4200000 | | F | 10 | | TSCA | Yes | | HazardClass | 6.1(a) | | PackingGroup | II | | HS Code | 29215190 | | Toxicity | LD50 oral in bird - wild: 23700ug/kg |
| | N,N,N',N'-Tetramethyl-1,4-phenylenediamine Usage And Synthesis |
| Chemical Properties | purple to brown crystalline powder | | Uses | N,N,N',N'-Tetramethyl-p-phenylenediamine is a reducing co-substrate for heme peroxidases. It is used for detection of peroxidases on polyacrylamide gels. | | Uses | In the form of the hydrochloride as a reagent in analytical chemistry. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 29, p. 488, 1964 DOI: 10.1021/jo01025a506 | | General Description | Leaflets or a drab green solid. | | Air & Water Reactions | N,N,N',N'-Tetramethyl-1,4-phenylenediamine may be sensitive to air and heat. . Insoluble in water. | | Reactivity Profile | N,N,N',N'-Tetramethyl-1,4-phenylenediamine can burn in air to give toxic NOx gases . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. | | Health Hazard | ACUTE/CHRONIC HAZARDS: When heated to decomposition N,N,N',N'-Tetramethyl-1,4-phenylenediamine emits toxic fumes. It is an irritant. | | Fire Hazard | N,N,N',N'-Tetramethyl-1,4-phenylenediamine is probably combustible. | | Safety Profile | Poison by ingestion. Moderatelytoxic by inhalation. Mutation data reported. When heatedto decomposition it emits toxic fumes of NOx. | | Purification Methods | Crystallise the amine from pet ether or water. It can be sublimed or dried carefully in a vacuum line, and stored in the dark under nitrogen. It has been recrystallised from its melt. [Beilstein 13 H 74, 13 I 22, 13 II 40, 13 III 111, IV 107.] |
| | N,N,N',N'-Tetramethyl-1,4-phenylenediamine Preparation Products And Raw materials |
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