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Psoralen

Psoralen Suppliers list
Company Name: Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
Tel: +8618829768577
Email: gao490372054@gamil.com
Products Intro: Product Name:Psoralen
CAS:66-97-7
Purity:0.95;0.97;0.98;0.99 Package:mg;g;kg;t
Company Name: PNP Biotech Co. Ltd
Tel: +8618516098983
Email: sales@pnpbiotech.com
Products Intro: Product Name:Psoralen
CAS:66-97-7
Purity:99% Package:25kg;USD
Company Name: Chongqing Zhihe Biopharmaceutical Co., Ltd.
Tel: +86-18580541567 +86-17782035140
Email: sales@zhswyy.com
Products Intro: Product Name:Psoralen
CAS:66-97-7
Purity:>=98% Package:1kg;|5kg;|25kg
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Psoralen
CAS:66-97-7
Purity:HPLC>=98% Package:20mg/250mg
Company Name: career henan chemical co
Tel: +86-0371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:Psoralen
CAS:66-97-7
Purity:99% Package:1kg;2USD

Psoralen manufacturers

  • Psoralen
  • Psoralen pictures
  • $0.00 / 25kg
  • 2024-03-28
  • CAS:66-97-7
  • Min. Order: 25kg
  • Purity: 99%
  • Supply Ability: Inquiry
  • Psoralen
  • Psoralen pictures
  • $0.00 / 1kg
  • 2024-03-27
  • CAS:66-97-7
  • Min. Order: 0.10000000149011612kg
  • Purity: ≥98%
  • Supply Ability: 20tons
  • Psoralen
  • Psoralen pictures
  • $0.00 / 1kg
  • 2023-12-26
  • CAS:66-97-7
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 50000kg
Psoralen Basic information
Description References
Product Name:Psoralen
Synonyms:PSORALEN;Fructus Psoraleae extract;Psoralen, >=99%;TGRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRRY MJJNNNNNNN;Psoralea corylifolia Linn. Extract;furo(2’,3’,7,6)coumarin;furo(2’,3’:7’,6)coumarin;Furo(4',5',6,7)coumarin
CAS:66-97-7
MF:C11H6O3
MW:186.16
EINECS:200-639-7
Product Categories:chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Coumarins;Inhibitors
Mol File:66-97-7.mol
Psoralen Structure
Psoralen Chemical Properties
Melting point 160-162 °C
Boiling point 280.64°C (rough estimate)
density 1.2477 (rough estimate)
refractive index 1.6310 (estimate)
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
color White to Off-White
Water Solubility 65.16mg/L(25 ºC)
λmax328nm(EtOH)(lit.)
Merck 14,7928
BRN 152784
InChIKeyZCCUUQDIBDJBTK-UHFFFAOYSA-N
LogP1.670
CAS DataBase Reference66-97-7(CAS DataBase Reference)
NIST Chemistry Reference7H-furo[3,2-g][1]benzopyran-7-one(66-97-7)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26
WGK Germany 3
RTECS LV0944000
8-10
HS Code 29339900
Hazardous Substances Data66-97-7(Hazardous Substances Data)
MSDS Information
ProviderLanguage
SigmaAldrich English
Psoralen Usage And Synthesis
DescriptionPsoralen is a kind of naturally occurring furocoumarin. It is naturally occurred in the seeds of Psoralea corylifolia as well as in the common fig, celery, parsley, West Indian Satinwood and all citrus fruits. It is capable of binding to DNA via single- and double-strand cross-linking upon photoactivation with UV radiation. It can intercalate with DNA, blocking its synthesis and cell division. For this reason, it is an important mutagen and can be used in related molecular biology studies. It also exhibits anti- proliferative, anti-allergenic and anti-histamine functions. It can also be used in PUVA treatment for skin diseases such as psoriasis, eczema and vitiligo. It is also effective tanning activator in sunscreens. Some of its derivatives, e.g. amino-psoralen, amotosalen HCl, can even inactivate pathogens in blood products.
Referenceshttps://en.wikipedia.org/wiki/Psoralen
https://pubchem.ncbi.nlm.nih.gov/compound/Psoralen#section=Top
Chemical PropertiesCrystalline Solid
UsesUse as photochemical probe in biological systems
UsesPsoralens are phytoalexins; they are used by plants in a defensive response to attacks by fungi and insects. They have also shown photosensitizing and phototoxic effects in animals and humans and have been used in photochemotherapy for management of vitiligo, psoriasis, and mycosis fungoides. Used as photochemical probe in biological systems.
UsesAs photochemical probe in biological systems: P.-S. Song, C.-N. Ou, Ann. N.Y. Acad. Sci. 346, 355 (1980).
DefinitionChEBI: The simplest member of the class of psoralens that is 7H-furo[3,2-g]chromene having a keto group at position 7. It has been found in plants like Psoralea corylifolia and Ficus salicifolia.
Synthesis Reference(s)Journal of the American Chemical Society, 106, p. 6735, 1984 DOI: 10.1021/ja00334a044
Synthetic Communications, 37, p. 63, 2007 DOI: 10.1080/00397910600978093
Biochem/physiol ActionsPsoralen belongs to the linear type furanocoumarins. It intercalates and induces interstrand cross-links in DNA. On UV exposure psoralen is excited leading to irreversible intercalation with DNA by covalent bond formation. This property of psoralen ultraviolet A light (PUVA) is exploited in treating skin diseases and cutaneous T-cell lymphoma. However, usage psoralen also leads to hepatotoxicity and cytotoxicity by the generation of psoralen photoproducts (POPs). It may be useful in treating osteoporosis
Tag:Psoralen(66-97-7) Related Product Information
Coumarin 2-Oxo-(2H)-furo(2,3-h)-1-benzopyran Psoralen-mop BAVACHIN Bergapten BERGAPTOL psoralen,4,5’,8-trimethyl Imperatorin Bergamotine OXYPEUCEDANIN ISOPIMPINELLIN 3-(HYDROXYMETHYL)-2,5,9-TRIMETHYL-7H-FURO[3,2-G][1]BENZOPYRAN-7-ONE ALLOISOIMPERATORIN XANTHOTOXOL Isoimperatorin BYAKANGELICIN 3-(alpha,alpha-dimethylallyl)psoralen 7H-Furo3,2-g1benzopyran-7-one, 3-methoxy-2-(1-methylethyl)-