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化学名: | DL-パンテノール | 英語化学名: | Panthenol | 别名: | 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-,(+-)-Butanamide;4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-(+-)-butanamid;4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-(+-)-butyramid;4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-(+/-)-butanamid;4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-dl-butyramid;DL-2 4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3 3-DIMETHYLBUTYRAMIDE;DL-N-PANTOYL-E-PROPANOLAMINE;DL-PANTOTHENOL | CAS番号: | 16485-10-2 | 分子式: | C9H19NO4 | 分子量: | 205.25 | EINECS: | 240-540-6 | カテゴリ情報: | Vitamin Ingredients;Pharmaceutical Intermediates;Inhibitors;ZENTINIC | Mol File: | 16485-10-2.mol | |
融点 | 66-69 °C (lit.) | 比旋光度 | 0°(c=5, H2O) | 沸点 | 118-120 °C(Press: 0.02 Torr) | 比重(密度) | 1.166±0.06 g/cm3(Predicted) | 蒸気圧 | 0.004Pa at 25℃ | 貯蔵温度 | Inert atmosphere,Room Temperature | 溶解性 | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly) | 酸解離定数(Pka) | 13.03±0.20(Predicted) | 色 | White to Off-White | 水溶解度 | Soluble in water, ethanol, ether, chloroform, and propylene glycol. | Sensitive | Hygroscopic | Merck | 14,2947 | BRN | 1724945 | InChIKey | SNPLKNRPJHDVJA-UHFFFAOYSA-N | LogP | -1.02 at 22℃ | CAS データベース | 16485-10-2(CAS DataBase Reference) | EPAの化学物質情報 | Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl- (16485-10-2) |
| DL-パンテノール Usage And Synthesis |
外観 | 白色~微褐色、結晶性粉末~粉末 | 定義 | 本品は、次の化学式で表されるアミドアルコールである。 | 用途 | 有機合成原料。 | 化粧品の成分用途 | ヘアコンディショニング剤、保湿.湿潤剤、溶剤 | 効能 | ビタミンB5補充薬 | 使用 | vitamin B5 precursor, radioprotectant, antimalarial | 使用 | DL-Panthenol is used in the topical treatment of skin disorders, such as minor irritations and skin burns. Also used in the strengthening and treatment of hair. | 使用 | panthenol (pro-vitamin B5) acts as a penetrating moisturizer. Panthenol appears to stimulate cellular proliferation and aid in tissue repair. Studies indicate that when topically applied, panthenol penetrates the skin and gets converted into pantothenic acid, a B complex vitamin. Such action could possibly influence the skin’s natural resources of pantothenic acid. It imparts a nonirritant, non-sensitizing, moisturizing, and conditioning feel and promotes normal keratinization and wound-healing. Panthenol protects the skin against sunburn, provides relief for existing sunburn, and enhances the natural tanning process. Panthenol’s humectant character enables it to hold water in the product or attract water from the environment, resulting in a moisturizing effect. It enhances skin suppleness, and claims are that it also acts as an anti-inflammatory agent. It is considered a non-comedogenic raw material. | 一般的な説明 | Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists in two optically active forms, both of which are used in pharmaceutical preparations. While pantothenic acid is optically active, only the dextrorotatory form is biologically active. Dexpanthenol, the active form of panthenol, is enzymatically cleaved to form pantothenic acid (Vitamin B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium. | 燃焼性と爆発性 | Non flammable |
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