DL-パンテノール(16485-10-2)

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DL-パンテノール 製品概要
化学名:DL-パンテノール
英語化学名:Panthenol
别名:2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl-,(+-)-Butanamide;4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-(+-)-butanamid;4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-(+-)-butyramid;4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-(+/-)-butanamid;4-dihydroxy-n-(3-hydroxypropyl)-3,3-dimethyl-dl-butyramid;DL-2 4-DIHYDROXY-N-(3-HYDROXYPROPYL)-3 3-DIMETHYLBUTYRAMIDE;DL-N-PANTOYL-E-PROPANOLAMINE;DL-PANTOTHENOL
CAS番号:16485-10-2
分子式:C9H19NO4
分子量:205.25
EINECS:240-540-6
カテゴリ情報:Vitamin Ingredients;Pharmaceutical Intermediates;Inhibitors;ZENTINIC
Mol File:16485-10-2.mol
DL-パンテノール
DL-パンテノール 物理性質
融点 66-69 °C (lit.)
比旋光度 0°(c=5, H2O)
沸点 118-120 °C(Press: 0.02 Torr)
比重(密度) 1.166±0.06 g/cm3(Predicted)
蒸気圧0.004Pa at 25℃
貯蔵温度 Inert atmosphere,Room Temperature
溶解性Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
酸解離定数(Pka)13.03±0.20(Predicted)
White to Off-White
水溶解度 Soluble in water, ethanol, ether, chloroform, and propylene glycol.
Sensitive Hygroscopic
Merck 14,2947
BRN 1724945
InChIKeySNPLKNRPJHDVJA-UHFFFAOYSA-N
LogP-1.02 at 22℃
CAS データベース16485-10-2(CAS DataBase Reference)
EPAの化学物質情報Butanamide, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethyl- (16485-10-2)
安全性情報
主な危険性 Xn
Rフレーズ 36/37/38-48-41-37/38-20/21/22
Sフレーズ 26-37-45-36/37/39-22
WGK Germany 3
RTECS 番号ES4316500
3
TSCA Yes
HSコード 29362400
毒性mouse,LD50,intraperitoneal,10100mg/kg (10100mg/kg),Farmaco, Edizione Scientifica. Vol. 14, Pg. 43, 1959.
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
DL-パンテノール Usage And Synthesis
外観白色~微褐色、結晶性粉末~粉末
定義本品は、次の化学式で表されるアミドアルコールである。
用途有機合成原料。
化粧品の成分用途ヘアコンディショニング剤、保湿.湿潤剤、溶剤
効能ビタミンB5補充薬
使用vitamin B5 precursor, radioprotectant, antimalarial
使用DL-Panthenol is used in the topical treatment of skin disorders, such as minor irritations and skin burns. Also used in the strengthening and treatment of hair.
使用panthenol (pro-vitamin B5) acts as a penetrating moisturizer. Panthenol appears to stimulate cellular proliferation and aid in tissue repair. Studies indicate that when topically applied, panthenol penetrates the skin and gets converted into pantothenic acid, a B complex vitamin. Such action could possibly influence the skin’s natural resources of pantothenic acid. It imparts a nonirritant, non-sensitizing, moisturizing, and conditioning feel and promotes normal keratinization and wound-healing. Panthenol protects the skin against sunburn, provides relief for existing sunburn, and enhances the natural tanning process. Panthenol’s humectant character enables it to hold water in the product or attract water from the environment, resulting in a moisturizing effect. It enhances skin suppleness, and claims are that it also acts as an anti-inflammatory agent. It is considered a non-comedogenic raw material.
一般的な説明Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists in two optically active forms, both of which are used in pharmaceutical preparations. While pantothenic acid is optically active, only the dextrorotatory form is biologically active. Dexpanthenol, the active form of panthenol, is enzymatically cleaved to form pantothenic acid (Vitamin B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium.
燃焼性と爆発性Non flammable
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