- Tamarixetin
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- $0.00 / 5mg
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2023-02-24
- CAS:603-61-2
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
- TAMARIXETIN
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- $1.00 / 1KG
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2019-07-06
- CAS:603-61-2
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 100KG
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| | TAMARIXETIN Basic information |
| Product Name: | TAMARIXETIN | | Synonyms: | 3,3',5,7 TETRAHYDROXY-4'-METHOXYFLAVONE;TAMARIXETIN;QUERCETIN-4'-METHYL ETHER;3,3’,5,7-tetrahydroxy-4’-methoxy-flavon;QUERCETIN-4''-METHYL ETHER hplc;3,5,7-Trihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one;Chiosmethin;4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(3-hydroxy-4-methoxyphenyl)- | | CAS: | 603-61-2 | | MF: | C16H12O7 | | MW: | 316.26 | | EINECS: | 210-050-7 | | Product Categories: | Aromatics;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Flavanols | | Mol File: | 603-61-2.mol |  |
| | TAMARIXETIN Chemical Properties |
| Melting point | 265-268°C | | Boiling point | 601.8±55.0 °C(Predicted) | | density | 1.634±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: Slightly Soluble; Methanol: Slightly Soluble | | form | A solid | | pka | 6.31±0.40(Predicted) | | LogP | 2.420 (est) |
| Risk Statements | 22 | | Safety Statements | 22-45 |
| | TAMARIXETIN Usage And Synthesis |
| Description | 4''-O-methyl Quercetin is a flavonoid isolated from C. ordata with anticancer and antiplasmodial activity. 4''-O-methyl Quercetin is a major metabolite of quercetin (Item No. 10005169) that inhibits the viability of HL-60, U937, MOLT-3, Raji, K562, MCF-7, SK-MEL-1, and A549 human tumor cell lines with IC50 values ranging from 5.5-24.1 μM. It induces G2-M arrest and inhibits tubulin polymerization in vitro in a dose-dependent manner. 4''-O-methyl Quercetin inhibits breast cancer resistance protein (BCRP/ABCG2; IC50 = 40 nM in a vesicular transport assay) with no cellular toxicity indicating potential for use in overcoming multidrug resistance in chemotherapy. 4''-O-methyl Quercetin also reduces in vitro proliferation of chloroquine-resistant P. falciparum (IC50 = 4.8 μM) and suppresses infection in mice (65-81% suppression at 2.5-5 mg/kg dose). | | Uses | A major metabolite of the flavanoid Quercetin (Q509500) with antioxidant properties. It helps to protect H9c2 cardiomyoblasts against H2O2-induced oxidative stress via the modulation of PI3K/Akt and ERK1/2 signaling pathways. | | Definition | ChEBI: A monomethoxyflavone that is quercetin methylated at position O-4'. Isolated from Cyperus teneriffae. | | General Description | This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG |
| | TAMARIXETIN Preparation Products And Raw materials |
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