Daltroban manufacturers
- Daltroban USP/EP/BP
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- $1.10 / 1g
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2021-08-05
- CAS:79094-20-5
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons min
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| | Daltroban Basic information |
| Product Name: | Daltroban | | Synonyms: | SKF-96148;2-[4-[2-(4-chlorophenyl)sulfonylaminoethyl]phenyl]acetic acid;4-[2-[(4-CHLOROPHENYLSULFONYL)AMINO]ETHYL]BENZENEACETIC ACID;BM-13505;DALTROBAN;DatelliptiumChloride;4-[2-[(4-Chlorophenylsulfonyl)amino]ethyl]benzeneacetic acid, BM-13505, SKF-96148;4-[2-(4-Chlorobenzene-sulfonamido)ethyl]benzeneacetic acid | | CAS: | 79094-20-5 | | MF: | C16H16ClNO4S | | MW: | 353.82 | | EINECS: | | | Product Categories: | | | Mol File: | 79094-20-5.mol |  |
| | Daltroban Chemical Properties |
| Melting point | 132.5-137.4 °C(lit.) | | Boiling point | 555.3±60.0 °C(Predicted) | | density | 1.378±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 22 mg/mL, soluble | | form | A solid | | pka | 4.33±0.10(Predicted) | | color | white | | InChI | InChI=1S/C16H16ClNO4S/c17-14-5-7-15(8-6-14)23(21,22)18-10-9-12-1-3-13(4-2-12)11-16(19)20/h1-8,18H,9-11H2,(H,19,20) | | InChIKey | IULOBWFWYDMECP-UHFFFAOYSA-N | | SMILES | C1(CC(O)=O)=CC=C(CCNS(C2=CC=C(Cl)C=C2)(=O)=O)C=C1 | | CAS DataBase Reference | 79094-20-5(CAS DataBase Reference) |
| | Daltroban Usage And Synthesis |
| Description | Daltroban (BM 13505, SKF 96148), a specific thromboxane A2 receptor antagonist, was studied as an antithrombotic agent. Daltroban increases intracellular calcium in vascular smooth muscle cells. Daltroban shows a protective effect in reperfusion injury. The drug was licensed to Smith Kline Beecham and underwent phase III clinical trials in the UK and Germany as an antithrombotic agent but did not enter clinical trials in the USA. Besides, вaltroban was investigated in patients with an ischemic heart disorder. However, the development of daltroban has been discontinued.
| | Uses | Immunosuppressant. | | Uses | Daltroban can be used as a2 receptor to target adipose-derived stem cell for treating ischemic diseases. |
| | Daltroban Preparation Products And Raw materials |
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