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Sibutramine hydrochloride

Sibutramine hydrochloride Suppliers list
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Products Intro:Product Name:SibutraMine hydrochloride;1-(4-Chlorophenyl)-N,N-diMethyl-α-(2-Methylpropyl)cyclobutaneMethanaMinehydrochloride
CAS:84485-00-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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Products Intro:Product Name:Sibutramine Hydrochloride
CAS:84485-00-7
Purity:>99% Package:1kg/bag,or as your request
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Products Intro:CAS:84485-00-7
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Products Intro:Product Name:SibutraMine HCl
CAS:84485-00-7
Purity:99% Package:1g;5g
Sibutramine hydrochloride Basic information
Weight loss pills Precautions Uses
Product Name:Sibutramine hydrochloride
Synonyms:SIBUTRAMINE HCL;SIBUTRAMINE HYDROCHLORIDE;REDUCTIL;BTS 54524;MERIDIA;1-(4-CHLOROPHENYL)-N,N-DIMETHYL-BETA-(2-METHYLPROPYL)CYCLOBUTANEMETHANAMINE HYDROCHLORIDE;SIBUTRAMINE HCL ENTERPRISE STANDARD HPLC 99%;SIBUTRAMINE HCL MONOHYDRATE 99.6+%
CAS:84485-00-7
MF:C17H27Cl2N
MW:316.31
EINECS:
Product Categories:APIs;Weight Loss;Pharmaceutical intermediate
Mol File:84485-00-7.mol
Sibutramine hydrochloride Structure
Sibutramine hydrochloride Chemical Properties
Melting point 190-200°C
storage temp. Store at RT
CAS DataBase Reference84485-00-7(CAS DataBase Reference)
Safety Information
MSDS Information
Sibutramine hydrochloride Usage And Synthesis
Weight loss pillsSibutramine hydrochloride is a weight loss drug, it is hydrochloride salt form of sibutramine , and the pharmacological effects are fully consistent with of sibutramine , but the stability and solubility are better than sibutramine.
Sibutramine hydrochloride is firstly used to treat depression, in their clinical application process , people find that the effect of weight loss is significantly stronger than the effect of the antidepressant . On one hand ,by inhibiting the reuptake of serotonin, which makes the body reduce hunger, it can suppress appetite and control caloric intake effectively ; on the other hand, by activating the adrenergic receptors, which increases adipose tissue consumption, it can increase metabolism and energy consumption;it has obvious weight loss effect, but it may cause endangering serious side effects such as high blood pressure, high heart rate, anorexia, insomnia, abnormal liver function.
The above information is edited by the chemicalbook of Tian Ye.
PrecautionsSibutramine hydrochloride belongs to the serotonin and norepinephrine reuptake inhibitors, it has the dual role of inhibiting appetite and enhancing metabolism, it can be used for the treatment of obesity which diet and exercise can not control.
There are many taboos in clinical practice of sibutramine hydrochloride , for example, patients with severe hypertension or patients with severe liver and kidney dysfunction, or patients with angle-closure glaucoma and women after childbirth, should not use it . Because the physiological effects of 16 years old or younger minors have not yet been confirmed, use of it should be prohibited. Also doses should be strictly controlled by users, the recommended starting dose is 10 mg per day for adults, the maximum should not exceed 15 mg. If there is overdose, patients should go to hospital for treatment, there is no specific antidote, only symptomatic treatment can be taken in clinic.
UsesIt is used as an antidepressant.
Biological Activity5-HT and noradrenalin re-uptake inhibitor (SNRI). Produces weight loss in rats via inhibition of food intake and increased energy expenditure. Antidepressant.
Sibutramine hydrochloride Preparation Products And Raw materials
Preparation ProductsSibutramine
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