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| | CITRATE SYNTHASE Basic information |
| Product Name: | CITRATE SYNTHASE | | Synonyms: | EC 4.1.3.7;CITRATE CONDENSING ENZYME;CITRATE SYNTHASE;CITRATE OXALOACETATELYASE;CITRATE OXALOACETATE LYASE [COA-ACETYLATING;citrate synthase from chicken heart;citrate synthase from porcine heart;citrate synthase from thermoplasma*acidophilum | | CAS: | 9027-96-7 | | MF: | C6H5O7-3 | | MW: | 189.0997 | | EINECS: | 232-821-7 | | Product Categories: | Lyases;Specialty Enzymes | | Mol File: | 9027-96-7.mol |  |
| | CITRATE SYNTHASE Chemical Properties |
| storage temp. | 2-8°C | | solubility | H2O: soluble1.0mg/mL, clear | | form | ammonium sulfate suspension |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Toxicity | A fine powder
used in riot control because of its property of inducing acute
irritation to the eyes, to any skin abrasion and to the tissues of
the respiratory passages, causing coughing and nausea. |
| | CITRATE SYNTHASE Usage And Synthesis |
| Uses | Citrate Synthase from porcine heart has been used:
- to inject newt egg for determining its importance in egg activation at fertilization
- in the preparation of reaction mix to determine pyruvate carboxylase enzyme activity
- to examine whether it can induce a [Ca2+]?increase and egg activation in unfertilized eggs
| | Definition | An enzyme that catalyzes the condensation of
oxaloacetic acid and acetyl-CoA to yield citric acid
and coenzyme A. | | Biochem/physiol Actions | Citrate synthase catalyses the conversion of citrate to acetyl-CoA in the presence of coenzyme-A with the release of H2O and oxaloacetate. The enzyme has a molecular weight of 85 kDa and a pI of 6.1-6.6. It is inhibited by fluoroacetyl-CoA, palmitoyl-CoA, and citroyl-CoA. It is also inhibited when it is acetylated by acetic anhydride or iodinated by iodine. |
| | CITRATE SYNTHASE Preparation Products And Raw materials |
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