基本信息
| 中文名称 | Nalfurafine hydrochloride |
|---|---|
| 中文同义词 | |
| 英文名称 | Nalfurafine hydrochloride |
| 英文同义词 | Nalfurafine-d3 Hydrochloride;Nalfurafine Hydrochloride |
| CAS号 | |
| 分子式 | C28H33ClN2O5 |
| 分子量 | 513.02502 |
| EINECS号 | |
| 相关类别 | Agonists;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Neurochemicals;Pharmaceuticals |
| Mol文件 | Mol File |
| 结构式 |  |
Nalfurafine hydrochloride 性质
用途
Nalfurafine hydrochloride was launched on March of 2009 in Japan as the first in class non-narcotic opioid drug for intractable itch caused by hemodialysis. It showed significant opioid κ-agonist acti vity and induced neither aversion nor preference in rats on the CPP (Conditioned Place Preference) test. Controlled Substance. A new therapeutic agent for the treatment of uremic pruritus in hemodialy sis patients.