- Piperazine Citrate
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- $0.00 / 1kg
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2024-04-16
- CAS:144-29-6
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10000kg
- Piperazine citrate
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- $30.00 / 10BOX
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2024-03-31
- CAS:144-29-6
- Min. Order: 10BOX
- Purity: 99
- Supply Ability: 20TONS
- PIPERAZINE CITRATE
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- $0.00 / 25KG
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2023-09-07
- CAS:144-29-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
Related articles - Side effects of Piperazine citrate
- Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms.Piperazine belon....
- Jan 11，2022
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| | Piperazine citrate Basic information |
| | Piperazine citrate Chemical Properties |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 1 | | RTECS | TL3485000 | | HS Code | 29335990 |
| | Piperazine citrate Usage And Synthesis |
| Description | Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged compound. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. Piperazine was first introduced as an anthelmintic in 1953. Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism. | | Chemical Properties | Piperazine citrate is a white, crystalline powder, with not more than a slight odor. It is soluble in water, and insoluble in alcohol and in ether. | | Uses | Piperazine Citrate is an anthelmintic agent used in the treatment of parasitic infections. Also used in the reduction of blood pressure. | | Indications | Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children. | | Brand name | Antepar (GlaxoSmithKline); Bryrel (Sanofi
Aventis). | | Flammability and Explosibility | Not classified | | Mechanism of action | Piperazine is a GABA receptor agonist. Piperzine binds directly and selectively to muscle membrane GABA receptors, presumably causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis. | | Pharmacokinetics | Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines. |
| | Piperazine citrate Preparation Products And Raw materials |
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