- BIS-Tris
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- $5.00 / 1KG
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2024-04-16
- CAS:6976-37-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- Bis-Tris
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- $0.00 / 1kg
-
2024-02-20
- CAS:6976-37-0
- Min. Order: 1kg
- Purity: 0.995
- Supply Ability: 1000tons
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| | BIS-Tris Basic information |
| Product Name: | BIS-Tris | | Synonyms: | 2,2-BIS(HYDROXYETHYL)-(IMINOTRIS)-(HYDROXYMETHYL)-METHANE;2-BIS[2-HYDROXYETHYL]AMINO-2-[HYDROXYMETHYL]1,3-PROPANEDIOL;2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-3-propanediol;Bis Tris Bis(2-hydroxyethyl)imino-tris(hydroxymethyl)methane;Bis Tris, Molecular Biology Grade Bis(2-hydroxyethyl)imino-tris(hydroxymethyl)methane, Molecular Biology Grade;Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane~Bis-TRIS;Bis-Tris (2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol);BIS-TRIS BIOULTRA, >= 99.0% (NT) | | CAS: | 6976-37-0 | | MF: | C8H19NO5 | | MW: | 209.24 | | EINECS: | 230-237-7 | | Product Categories: | Buffer;API intermediates | | Mol File: | 6976-37-0.mol |  |
| | BIS-Tris Chemical Properties |
| Melting point | 104 °C(lit.) | | Boiling point | 466.2±40.0 °C(Predicted) | | density | 1.346±0.06 g/cm3(Predicted) | | vapor pressure | 0Pa at 25℃ | | storage temp. | Inert atmosphere,Room Temperature | | solubility | H2O: 1 M at 20 °C, clear, colorless | | form | Solution | | color | Yellow to orange | | PH | 9.0-10.1 (20-25℃, 1M in water) | | pka | 6.5(at 25℃) | | PH Range | 5.8 - 7.2 | | Odor | Odorless | | Water Solubility | soluble | | Sensitive | Air Sensitive | | λmax | λ: 280 nm Amax: 0.15 | | BRN | 2205275 | | InChIKey | OWMVSZAMULFTJU-UHFFFAOYSA-N | | LogP | -2.26 at 20℃ | | CAS DataBase Reference | 6976-37-0(CAS DataBase Reference) | | EPA Substance Registry System | 1,3-Propanediol, 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)- (6976-37-0) |
| | BIS-Tris Usage And Synthesis |
| Chemical Properties | White/clear crystalline powder | | Uses | Bis Tris is a commonly used biological buffer for very broad usage in biological systems such as diagnostics, electrophoresis and protein based bioprocessing. The pKa of Bis Tris is 6.36 which makes it a good candidate for biological-based formulations.
Bis Tris is used in a wide variety of biological applications including protein separation buffers, cell culture media, electrophoresis separations and diagnostic reagent formulations. | | Uses | It is used as a biological buffer, organic synthesize, chemical & pharmaceutical intermediate. It is suitable for fractionation of hemoglobin. | | Uses | Bis-Tris, also known as bis-Tris methane, is a zwitterionic buffering agent used in biochemistry and molecular biology. It is a bis(2-hydroxyethyl)amine and Tris family buffer. Bis Tris is a common component of many buffer systems for various types of electrophoresis. Bis-Tris may form a complex with some common metals, such as Cu(II) and Pb(II), and formation constants should be taken into account when using this buffer in a solution containing metal ions. Bis-Tris can be used as a substitute for the highly toxic buffer cacodylate. | | Definition | ChEBI: Bis-tris is a buffer substance useful for calibration of glass electrodes and for the preparation of the biochemical and biological buffer solutions; pKa = 6.46 at 25 ℃. It has a role as a buffer. It is functionally related to a member of tris. | | Flammability and Explosibility | Not classified | | Purification Methods | Crystallise BIS-TRIS from hot 1-butanol and dry it in a vacuum at 25o. N,N-Bis-(2-hydroxyethyl)glycine (BICINE) See in “Amino Acids and Peptides”, Chapter 6. |
| | BIS-Tris Preparation Products And Raw materials |
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